Abstract
The effect of dose calculation accuracy for IMRT was studied by comparing different dose calculation algorithms. A head and neck IMRT plan was optimized using a superposition dose calculation algorithm. Dose was re-computed for the optimized plan using both Monte Carlo and pencil beam dose calculation algorithms to generate patient and phantom dose distributions. Tumor control probabilities (TCP) and normal tissue complication probabilities (NTCP) were computed to estimate the plan outcome. For the treatment plan studied, Monte Carlo best reproduces phantom dose measurements, the TCP was slightly lower than the superposition and pencil beam results, and the NTCP values differed little.
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© 2001 Springer-Verlag Berlin Heidelberg
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Siebers, J.V., Keall, P.J., Mohan, R. (2001). The Impact of Monte Carlo Dose Calculations on Intensity-Modulated Radiation Therapy. In: Kling, A., Baräo, F.J.C., Nakagawa, M., Távora, L., Vaz, P. (eds) Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and Applications. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18211-2_34
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DOI: https://doi.org/10.1007/978-3-642-18211-2_34
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