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Selenoprotein Mimics and Diseases

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Selenoproteins and Mimics

Part of the book series: Advanced Topics in Science and Technology in China ((ATSTC))

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Abstract

Selenium is an essential trace element for humans and animals. It plays a putative role in the prevention of cancer and some other diseases. GPx generally catalyze the reduction of peroxides mainly using glutathione as the electron donor, thus contributing to the body’s defence against free radicals. In the above chapters, we described some GPx mimics that were synthesized in different ways. These GPx mimics possess their own advantages and disadvantages respectively. However, some of them display remarkable antioxidant ability which indicates that they are promising candidates for medicinal applications. In this chapter, we will mainly describe the biological effect of these GPx mimics in different levels (organelles, cells and animals) and in different model systems.

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Authors and Affiliations

  1. Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, 310058, Hangzhou, China

    Ying Mu

  2. Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, 130012, Changchun, China

    Fei Yan & Ying Mu

Authors
  1. Fei Yan
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  2. Ying Mu
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© 2011 Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg

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Yan, F., Mu, Y. (2011). Selenoprotein Mimics and Diseases. In: Selenoproteins and Mimics. Advanced Topics in Science and Technology in China. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22236-8_20

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