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Mechanical DNA Devices

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Nucleic Acid Nanotechnology

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 29))

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Abstract

Natural molecular machines have been playing very significant roles in the world, which stimulated numerous efforts on the artificial molecular machines. DNA ambiguously is an ideal building block for the nanomechanical devices, because of many intriguing features. In this chapter, we first introduce the fundamental elements for understanding and implementing DNA-based nanomachines, such as fuels, dynamic behaviors, and the characterization methods. Furthermore, we describe the development of DNA nanomachines from simple constructs and operations to the sophisticated machinery systems concerning the coherent activation of multiple devices and configurational complexity. In the end, some important applications of DNA mechanical devices are discussed, including molecular transporting, organic synthesis, molecular sensing, and controlled drug delivery. Through this chapter, we aim to promote the fast advancement of the field of the nanomachines, which may push forward the multidisciplinary and interdisciplinary researches.

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Authors and Affiliations

  1. National Center for Nanoscience and Technology, Beijing, China

    Zhen-Gang Wang & Baoquan Ding

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  1. Zhen-Gang Wang
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  2. Baoquan Ding
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Correspondence to Baoquan Ding .

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Editors and Affiliations

  1. Dept. of Molecular Biology, University of Aarhus, Center for DNA Nanotechnology, Interdisciplinary Nanoscience Center, Aarhus C, Denmark

    Jørgen Kjems

  2. Center for DNA Nanotechnology, Interdisciplinary Nanoscience Center, Aarhus University, Aarhus C, Denmark

    Elena Ferapontova

  3. Center for DNA Nanotechnology, Interdisciplinary Nanoscience Center and Department of Chemistry, Aarhus University, Aarhus C, Denmark

    Kurt V. Gothelf

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Wang, ZG., Ding, B. (2014). Mechanical DNA Devices. In: Kjems, J., Ferapontova, E., Gothelf, K. (eds) Nucleic Acid Nanotechnology. Nucleic Acids and Molecular Biology, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38815-6_8

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