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The Renal and Epithelial Actions of Adenosine

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Topics and Perspectives in Adenosine Research

Summary

Adenosine acts to modulate a complex array of physiologic processes in a wide variety of cell types. Perhaps no other organ demonstrates the diverse cellular action of adenosine better than the kidney. With its numerous types of tubular epithelia, endothelium, vascular smooth muscle, nerves, and hormonal secretory cells, the kidney has become an interesting model in which to develop a unified hypothesis to explain the diverse actions of adenosine as a cellular regulator. Recent technical advances allowing the isolation of large numbers of specific renal cell types have provided a means of identifying which renal cell types have adenosine receptors and what postreceptor mechanisms are involved in mediating the actions of adenosine.

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Author information

Authors and Affiliations

  1. Department of Physiology, Michigan State University, East Lansing, Michigan, USA

    W. S. Spielman & L. J. Arend

  2. Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

    J. N. Forrest Jr.

Authors
  1. W. S. Spielman
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  2. L. J. Arend
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  3. J. N. Forrest Jr.
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Editor information

Editors and Affiliations

  1. Physiologisches Institut, Universität München, Pettenkoferstraße 12, 8000, München 2, Federal Republic of Germany

    Eckehart Gerlach  & Bernhard Friedrich Becker  & 

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© 1987 Springer-Verlag Berlin Heidelberg

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Spielman, W.S., Arend, L.J., Forrest, J.N. (1987). The Renal and Epithelial Actions of Adenosine. In: Gerlach, E., Becker, B.F. (eds) Topics and Perspectives in Adenosine Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45619-0_20

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  • DOI: https://doi.org/10.1007/978-3-642-45619-0_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45621-3

  • Online ISBN: 978-3-642-45619-0

  • eBook Packages: Springer Book Archive

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