Abstract
There is broad agreement that microbes play an important role in the aetiology and pathogenesis of ulcerative colitis (UC), probably via an abnormal local immune response to one or several microbial antigens or metabolites; this is clearly in addition to their role in local tissue invasion and microabscess formation. However, numerous investigations have failed to identify either an aetiological agent or a consistent alteration in the composition or balance of the complex faecal microflora.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Hartley, M.G. et al. (1992). The Role of Intestinal Microbes in Ulcerative Colitis: Studies on the Rectal Mucosa-Associated Microflora. In: Givel, JC., Oates, G.D., Thomson, J.P.S. (eds) Updates in Colo-Proctology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51680-1_22
Download citation
DOI: https://doi.org/10.1007/978-3-642-51680-1_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-55327-4
Online ISBN: 978-3-642-51680-1
eBook Packages: Springer Book Archive