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Modulation of Skin Barrier Function

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New Trends in Allergy V

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Abstract

Clinical unaffected skin of patients suffering from atopic eczema is characterized by a high degree of disturbances of structural and functional properties of the stratum corneum [16, 19]. The aim of skin care during a clinical unaffected interval is the reconstruction of disturbed barrier function by substitution of moisturizing substances and lipids. The reconstruction of the barrier function of the skin is possible both by substitution of reduced lipid components and by stimulation of the epidermal lipid synthesis. Among the lipids fatty acids (FA) play an important role in the synthesis of epidermal lipids [5, 6, 13]. As linked to specific epidermal ceramides, they are involved in forming and maintaining the barrier function of the skin.

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Authors
  1. W. Wohlrab
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  2. C. Huschka
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  3. D. Fröde
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  4. J.-M. Schneider
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Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein Klinikum Rechts der Isar, Technische Universität München, Biedersteiner Straße 29, 80802, München, Germany

    Johannes Ring (Prof. Dr. Dr.) (Prof. Dr. Dr.)

  2. ZAUM—Zentrum für Allergie und Umwelt, Klin. Kooperationsgruppe Umweltdermatologie und Allergologie GSF, Technische Universität München, Biedersteiner Straße 29, 80802, München, Germany

    Heidrun Behrendt (Prof. Dr.) (Prof. Dr.)

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© 2002 Springer-Verlag Berlin Heidelberg

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Wohlrab, W., Huschka, C., Fröde, D., Schneider, JM. (2002). Modulation of Skin Barrier Function. In: Ring, J., Behrendt, H. (eds) New Trends in Allergy V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55994-5_15

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  • DOI: https://doi.org/10.1007/978-3-642-55994-5_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62768-2

  • Online ISBN: 978-3-642-55994-5

  • eBook Packages: Springer Book Archive

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