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Stoffwechselkrankheiten

  • Chapter
Gelenkpathologie

Zusammenfassung

Der Zusammenfassung von Pick [398] ist zu entnehmen, dass Gaucher [156] 1882 in seiner „Thèse de Paris“ das „Epithélioma primitif de la rate“ als idiopathische Milzhypertrophie ohne Leukämie beschrieb. Schlagenhaufer [453] erkannte 1907 das Leiden als „Systemerkrankung des lymphatisch-hämatopoetischen Apparates“, evtl. durch den „Tuberkelbacillus“ verursacht, und Marchand [298] begründete zeitgleich die Auffassung, dass es Folge der „Einlagerung einer fremdartigen Substanz“ ist. Das Fehlen eines Glukozerebrosid-abbauenden Enzyms [54] bzw. eine reduzierte Aktivität der Glukozerebrosidase [385] wurden später als Ursache ermittelt.

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  1. Universität Ulm Abt. Pathologie, Albert-Einstein-Allee 11, 89081, Ulm, Germany

    Professor Dr. med. Winfried Mohr

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Mohr, W. (2000). Stoffwechselkrankheiten. In: Gelenkpathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57071-1_6

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