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Targeting of Proteins to Lysosomes and Granules

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The Peroxidase Multigene Family of Enzymes

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Abstract

This chapter is intended to categorize and briefly explain delivery pathways to lysosomes and granules in mammalian cells and vacuoles in yeast cells while highlighting a few paradigms. It reflects recent developments in this area of research and covers only a fragment of the vast literature on the biogenesis of the lysosomal/vacuolar apparatus and the specialized sorting principles. The author apologizes to those whose contributions could not be included in this highly focused and brief treatise outlining different vesicular and non-vesicular routes of lysosomal targeting. Because of limited space, secondary literature and reviews are frequently cited and relevant literature on neurovesicles is omitted.

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Authors
  1. Andrej Hasilik
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Editors and Affiliations

  1. Department of Medicine, Charité Humboldt University of Berlin, Schumannstr. 20/21, Berlin, 10117, Germany

    Petro E. Petrides M.D., Ph.D.

  2. Inflammation Program and Departments of Medicine, University of Iowa and Veterans Affairs Medical Center, 200 Hawkins Drive SW 54 GH, Iowa City, IA, 52242, USA

    William M. Nauseef M.D.

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© 2000 Springer-Verlag Berlin Heidelberg

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Hasilik, A. (2000). Targeting of Proteins to Lysosomes and Granules. In: Petrides, P.E., Nauseef, W.M. (eds) The Peroxidase Multigene Family of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58314-8_2

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  • DOI: https://doi.org/10.1007/978-3-642-58314-8_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63535-9

  • Online ISBN: 978-3-642-58314-8

  • eBook Packages: Springer Book Archive

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