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Changes in Cytoplasmic Poly(A)-Rich RNA in WI-38 Cells Stimulated to Proliferate

  • Chapter
Fundamental Aspects of Neoplasia

Abstract

Several lines of evidence indicate that activization of the genome is one of the early events in the pre-replicative phase of WI-38 human diploid fibroblasts stimulated to proliferate by a change of medium (5,11,30,31). An increase in chromatin template activity occurs within 1 hr after stimulation and is paralleled by an increase in incorporation of [3H] uridine into nuclear RNA (ID.

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Authors
  1. A. M. Novi
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  2. R. Baserga
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Editor information

Editors and Affiliations

  1. Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, 70112, USA

    A. Arthur Gottlieb M.D. (Professor and Chairman) (Professor and Chairman)

  2. Institute of Microbiology, Rutgers University, New Brunswick, New Jersey, 08903, USA

    Otto J. Plescia Ph.D. (Professor of Immunochemistry) (Professor of Immunochemistry)

  3. The Medical Center, University of Alabama, Birmingham, Alabama, USA

    David H. L. Bishop Ph.D. (Professor of Microbiology) (Professor of Microbiology)

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© 1975 Springer-Verlag New York Inc.

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Novi, A.M., Baserga, R. (1975). Changes in Cytoplasmic Poly(A)-Rich RNA in WI-38 Cells Stimulated to Proliferate. In: Gottlieb, A.A., Plescia, O.J., Bishop, D.H.L. (eds) Fundamental Aspects of Neoplasia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66112-9_29

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  • DOI: https://doi.org/10.1007/978-3-642-66112-9_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66114-3

  • Online ISBN: 978-3-642-66112-9

  • eBook Packages: Springer Book Archive

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