Abstract
Cardiogenic shock following cardiac surgery may be unresponsive to intra-aortic balloon pumping (IABP). In such a situation circulatory assist devices have been shown to be effective in supporting the circulation. The systems being used either bypass the failing left ventricle (LV) using a simple roller pump (RP) from the left atrium to the aorta (AA-LVA) [3, 7, 11] or from the left ventricular apex to the aorta (LVAD) [8, 12]. A second group of devices employ an auxiliary ventricle from the LV apex to the aorta [1, 14] (LVAD). In addition to supporting circulation, cardiac assistance may result in the salvage of ischemic myocardium by increasing the oxygen supply to the demand ratio [4, 6]. Previous studies have shown the greater effectiveness of left ventricular assistance (LVA) [13] in reducing myocardial oxygen consumption compared to AA-LVA. Pennock and associates [15] showed that the effectiveness of different degrees of LVA was dependent on the size of the infarct. A previous study from this laboratory [9] showed that AA-LVA was effective in reducing infarct size in a small infarct model, but not in the large infarct model. The effects of LVA on infarct size were therefore studied and are contrasted with those of AA-LVA.
Supported by Grant HLO 6312–15 from the National Institute of Health and National Heart and Lung Institute (Department of Surgery, Saint Louis University).
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Laks, H., Standeven, J.W., Ott, R.A., Hahn, J.W., Willman, V.L. (1979). Servo-Controlled Cardiac Assistance: The Effects of Left Ventricular-to-Aortic and Left Atrial-to-Aortic Assistance on Infarct Size . In: Unger, F. (eds) Assisted Circulation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67268-2_22
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DOI: https://doi.org/10.1007/978-3-642-67268-2_22
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