Abstract
The vessel wall, the vessel content and its flow behaviour form a, highly complex regulative circuit, which is until now understood only in a few of its manifold interactions. The flow forces and the flow patterns for example are able to affect the formed blood elements as well as the vessel wall. The geometry and the biochemical metabolism of the vessel wall will in turn influence blood flow and properties of blood cells. All components that interact may be considered to be involved in atherogenesis. Amongst the formed elements of the blood, the platelets are suspected to play a paramount role in the development of arterial thrombosis and the early stages of arteriosclerosis.
Supported in parts by Fritz Thyssen Foundation, Cologne
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Blasberg, P., Wurzinger, L.J., Schmid-Schönbein, H. (1983). Microrheology of Thrombocyte Deposition: Effect of Stimulation, Flow Direction, and Red Cells. In: Schettler, G., Nerem, R.M., Schmid-Schönbein, H., Mörl, H., Diehm, C. (eds) Fluid Dynamics as a Localizing Factor for Atherosclerosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69085-3_13
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DOI: https://doi.org/10.1007/978-3-642-69085-3_13
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