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Morphology of Vessel Wall Changes After Microsurgical End- to-Side Anastomosis and Their Pharmacological Prevention

  • Conference paper
Extra-Intracranial Vascular Anastomoses Microsurgery at the Edge of the Tentorium

Part of the book series: Advances in Neurosurgery ((NEURO,volume 13))

Abstract

Morphological alterations in the arteries which are involved in extracranial-intracranial (EC/IC) anastomoses may be harmful to EC/IC bypass function. Only a limited number of human specimens of EC/IC anastomoses have been evaluated, by STEINBOK and co-workers (15) and BODOSI and MEREI (3). They described development of arteriosclerotic changes such as interruption of the internal elastic membrane (IEM) and (myo-)intimal hyperplasia (MIH) which, in some instances, led to a marked stenosis of the lumen of the arteries. However, arteriosclerosis occurs frequently in the superficial temporal arteries of EC/IC bypass patients (12), and therefore the finding of arteriosclerosis cannot necessarily be considered as postoperative development.

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References

  1. Albanese, V., Spadaro, A., Tomasello, F., et al.: Dynamics of endothelial repair in end-to-side microsurgical carotid anastomoses in rats: A scanning electron microscopic study. Neurol. Res. 3, 267–287 (1981)

    PubMed  CAS  Google Scholar 

  2. Amezcua, J.L., O’Grady, J., Salmon, J.A., Moncada, S.: Prolonged paradoxical effect of aspirin on platelet behaviour and bleeding time in man. Thromb. Res. 16, 69–79 (1979)

    Article  PubMed  CAS  Google Scholar 

  3. Bodosi, M., Merei, F.T.: Development of histological structure of microanastomosis. Presented at the 5th Int. Symp. on Microvasc. Anastomoses for Cerebral Ischemia, Vienna, Sept. 14–17, 1980 (Abstr. No. 24a)

    Google Scholar 

  4. Canadian Cooperative Study Group: A randomized trial of aspirin and sulfinpyrazone in threatened stroke. New Engl. J. Med. 299, 53–59 (1979)

    Google Scholar 

  5. Fishman, J.A., Ryan, G.B., Karnovsky, M.J.: Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening. Lab. Invest. 32, 339–351 (1975)

    PubMed  CAS  Google Scholar 

  6. Flaherty, J.T., Pierce, J.E., Ferrans, V.J., et al.: Endothelial nuclear patterns in the canine arterial tree with particular reference to hemodynamic events. Circ. Res. 30, 23–33 (1972)

    PubMed  CAS  Google Scholar 

  7. Fox, J.A., Hugh, A.E.: Localisation of atheroma: Theory based on boundary layer separation. Br. Heart J. 28, 388–399 (1966)

    Article  PubMed  CAS  Google Scholar 

  8. Fry, D.L.: Acute vascular endothelial changes associated with increased blood velocity gradients. Circ. Res. 22, 165–197 (1968)

    PubMed  CAS  Google Scholar 

  9. Gelderman, P.W., Berendsen, W.: Re-endothelialization of microvascular carotid end-to-side anastomoses in the rat — a scanning electron microscope study. J. Neurosurg. 51, 785–795 (1979)

    Article  PubMed  CAS  Google Scholar 

  10. Houle, S., Roach, M.R.: Flow studies in a rigid model of an aortorenal junction. Atherosclerosis 40, 231–244 (1981)

    Article  PubMed  CAS  Google Scholar 

  11. Mehdorn, H.M., Weinstein, P.R., Chater, N.L.: Vessel wall response to the end-to-side anastomosis. Stroke 9, 10 (1978)

    Article  Google Scholar 

  12. Mehdorn, H.M., Wiedemeyer, H., Reinhardt, V., et al.: Histologische Veränderungen der A. temporalis superficialis and ihre Bedeutung für die extra-intrakranielle Bypass-Operation. Neurochirurgia 26, 181–186 (1983)

    PubMed  CAS  Google Scholar 

  13. O’Grady, J., Moncada, S.: Aspirin: a paradoxical effect on bleeding-time (Letter to the editor). Lancet Oct 7, 780 (1978)

    Article  Google Scholar 

  14. Ross, R., Glomset, J.A.: The pathogenesis of atherosclerosis. New Engl. J. Med. 295, 396–377, 420–425 (1976)

    Article  PubMed  CAS  Google Scholar 

  15. Steinbok, P., Berry, K., Dolman, C.L.: Superficial temporal artery middle cerebral artery (STA-MCA) anastomosis. J. Neurosurg. 50, 377–381 (1979)

    Article  PubMed  CAS  Google Scholar 

  16. Weinstein, P.R., Mehdorn, H.M., Szabo, Z.: Microsurgical anastomosis. Vessel injury, regeneration and repair. In: Serafin, D., Buncke, H.J., Jr. (eds.) Microsurgical composite tissue transplantation, pp. 111–144. Mosby, St. Louis Toronto London 1979

    Google Scholar 

  17. Young, P.H., Imhoff, H.G., Chu, H.L.: Scanning electron microscopic evaluation of variably angled end-to-side microvascular anastomoses. Neurosurgery 12, 306–312 (1983)

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Abteilung für Neurochirurgie, Universitätsklinikum der Gesamthochschule Essen, Hufelandstraße 55, D-4300, Essen 1, Germany

    H. M. Mehdorn & W. Grote

  2. lnstitut für Neuropathologie, Universitätsklinikum der Gesamthochschule Essen, Hufelandstraße 55, D-4300, Essen 1, Germany

    S. Hickler & V. Reinhardt

  3. Anatomisches Institut, Universitätsklinikum der Gesamthochschule Essen, Hufelandstraße 55, D-4300, Essen 1, Germany

    K. Venjakob

Authors
  1. H. M. Mehdorn
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  2. S. Hickler
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  3. K. Venjakob
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  4. V. Reinhardt
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  5. W. Grote
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Editor information

Editors and Affiliations

  1. Neurochirurgische Klinik, Medizinischen Hochschule Hannover, Konstanty-Gutschow-Str. 8, D-3000, Hannover 61, Germany

    Hermann Dietz

  2. Neurochirurgische Klinik und Poliklinik, Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Germany

    Mario Brock

  3. Neurochirurgische Klinik, Universität Erlangen-Nürnberg, Schwabachanlage 6 (Kopfklinikum), D-8520, Erlangen, Germany

    Margareta Klinger

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© 1985 Springer-Verlag Berlin Heidelberg

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Mehdorn, H.M., Hickler, S., Venjakob, K., Reinhardt, V., Grote, W. (1985). Morphology of Vessel Wall Changes After Microsurgical End- to-Side Anastomosis and Their Pharmacological Prevention. In: Dietz, H., Brock, M., Klinger, M. (eds) Extra-Intracranial Vascular Anastomoses Microsurgery at the Edge of the Tentorium. Advances in Neurosurgery, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70603-5_17

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  • DOI: https://doi.org/10.1007/978-3-642-70603-5_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15615-4

  • Online ISBN: 978-3-642-70603-5

  • eBook Packages: Springer Book Archive

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