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Immunologic Aspects of Malignant Renal Disease

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Renal and Adrenal Tumors

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Abstract

The biology of human renal cell carcinoma (RCC) has long been considered to be influenced by the immune system of the tumor host. The observation of occasional spontaneous regression of metastases, their erratic growth, or their occasional late occurrence following nephrectomy were thought to be strong clinical arguments for this assumption. Ljunggren et al. (1959), reporting on a case of histologically proven spontaneous regression of lung metastases, already suggested “antibody actions” as a possible explanation for such a phenomenon. Although these clinical findings are exceedingly rare and in many cases not substantiated by histology, there is definite proof that spontaneous regression of lung metastases, rather than those at other organ sites, occurs in RCC.

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Authors
  1. R. Ackermann
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Editors and Affiliations

  1. Röntgendiagnostisches Zentralinstitut, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Eberhard Löhr

  2. Institut für Pathologie, Klinikum der Universität Essen, Hufelandstraße 55, D-4300, Essen, Germany

    Lutz-Dietrich Leder

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© 1987 Springer-Verlag Berlin Heidelberg

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Ackermann, R. (1987). Immunologic Aspects of Malignant Renal Disease. In: Löhr, E., Leder, LD. (eds) Renal and Adrenal Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71207-4_16

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  • DOI: https://doi.org/10.1007/978-3-642-71207-4_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71209-8

  • Online ISBN: 978-3-642-71207-4

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