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The Packaging of DNA in Bacteriophage Lambda

  • Conference paper
Bacterial Chromatin

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

The structure of bacteriophage lambda has been studied extensively by several groups using a variety of physical and chemical techniques. However, many aspects of bacteriophage structure remain unreasolved. It is not known how the DNA is arranged three-dimensionally within the capsid, nor is the mechanism of packaging understood. However, some general features of lambda structure have been discerned (Review: Earnshaw and Casjens 1980). For example, it is now well established that the DNA is somehow pushed into a preformed structure known as the prohead, rather than assembly of the capsid around the condensed DNA molecule (Hohn and Hohn 1974; Kaiser et al. 1975), or a concerted protein-DNA condensation mechanism as has been observed in the animal virus SV40 (Bina et al. 1983).

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Author information

Authors and Affiliations

  1. Department of Genetics and Development, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, NY, 10032, USA

    C. R. Cantor

Authors
  1. J. Welsh
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  2. C. R. Cantor
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Editor information

Editors and Affiliations

  1. Department of Cell Biology, Laboratory of Genetics, University of Camerino, I-62032, Camerino (MC), Italy

    Claudio O. Gualerzi

  2. Max-Planck-Institut für Molekulare Genetik, Ihnestraße 73, D-1000, Berlin 33, Germany

    Claudio O. Gualerzi  & Cynthia L. Pon  & 

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© 1986 Springer-Verlag Berlin Heidelberg

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Welsh, J., Cantor, C.R. (1986). The Packaging of DNA in Bacteriophage Lambda. In: Gualerzi, C.O., Pon, C.L. (eds) Bacterial Chromatin. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71266-1_4

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  • DOI: https://doi.org/10.1007/978-3-642-71266-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71268-5

  • Online ISBN: 978-3-642-71266-1

  • eBook Packages: Springer Book Archive

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