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Differences in the Amount of ‘Plaque-Material’ in the Outflow System of Eyes with Chronic Simple and Exfoliation Glaucoma

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Glaucoma Update III

Abstract

Within the cribriform layer of the trabecular meshwork of glaucomatous eyes, Rohen and Witmer (1972) found localized accumulations of extracellular material, which they termed ‘plaques’ or plaque-material. Theses plaques are found in normal eyes of elderly humans as well as in cases of chronic simple glaucoma. Tangential sections through the inner wall and the adjacent cribriform meshwork showed that theses plaques mainly consist of sagittal sections of elastic-like fibers and their sheath-material. Theses fibers form a delicate network within the cribriform layer which was called ‘cribriform plexus’ (Rohen et al. 1981). The plexus itself is connected with the endothelium of Schlemm’s canal or with remnants of basement membrane material by radially orientated fibrils, ‘connecting fibrils’ (Fig. 1).

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References

  • Ashton N, Shakib M, Collyer R, Black R (1965) Electron microscopic study of the Pseudoexfoliation of the lens capsule. I. Lens capsule and zonular fibers. Invest Ophthal 4:141–153

    PubMed  CAS  Google Scholar 

  • Bertelsen TJ (1966) Fibrillopathia epithelio-capsularis. The so-called senile exfoliation or Pseudoexfoliation of the anterior lens capsule. Acta Ophthal (Kbh) 44:737–750

    Article  Google Scholar 

  • Bertelsen TJ, Drablös PA, Flood PR (1964) The so-called senile exfoliation (Pseudoexfoliation) of the anterior lens capsule, a product of the lens epithelium. Fibrillopathia epithelio-capsularis. Acta Ophthal (Kbh) 42:1096–1113

    Article  CAS  Google Scholar 

  • Blackstad TW, Sunde OW, Traetteberg J (1960) On the ultrastructure of the deposits of Bussaca in eyes with glaucoma simplex and so-called senile exfoliation of the anterior lens capsule. Acta Ophthal (Kbh) 38:587–598

    Article  Google Scholar 

  • Busacca A (1928) Struktur und Bedeutung der Häutchenniederschläge in der vorderen und hinteren Augenkammer. Graefes Arch Ophthalmol 119:135

    Google Scholar 

  • Dvorak-Theobald G (1954) Pseudo-exfoliation of the lens capsule. Amer J Ophthal 37:1–12

    PubMed  CAS  Google Scholar 

  • Lütjen-Drecoll E, Dietl T, Futa R, Rohen JW (1982) Age changes of the trabecular meshwork, a preliminary morphometric study. Hollyfield JG (ed) The structure of the eye. Elsevier Biomedical, New York Amsterdam Oxford, pp 341–348

    Google Scholar 

  • Lütjen-Drecoll E, Shimizu T, Rohrbach M, Rohen JW (1986a) Quantitative analysis of “plaque material” in the inner-and outer wall of Schlemm’s canal in normal-and glaucomatous eyes. Exp Eye Res 42:443–455

    Article  PubMed  Google Scholar 

  • Lütjen-Drecoll E, Shimizu T, Rohrbach M, Rohen JW (1986b) Quantitative analysis of “plaque material” between ciliary muscle tips in normal-and glaucomatous eyes. Exp Eye Res 42:457–465

    Article  PubMed  Google Scholar 

  • Ringvold A (1970) Ultrastructure of exfoliation material (Bussaca deposits) Virchows Arch Abt A (Path Anat) 350:95–104

    Article  CAS  Google Scholar 

  • Rohen JW, Witmer R (1972) Electron microscopic studies on the trabecular meshwork in glaucoma simplex. Albrecht von Graefes Arch Klin Exp Ophthalmol 183:251–266

    Article  PubMed  CAS  Google Scholar 

  • Rohen JW, Futa R, Lütjen-Drecoll E (1981) The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections. Invest Ophthalmol Vis Sci 21:574–585

    PubMed  CAS  Google Scholar 

  • Sugar S (1984) Pigmentary glaucoma and the glaucoma associated with the exfoliation-pseudoex-foliation syndrome: Update. Ophthalmology 91:307–310

    PubMed  CAS  Google Scholar 

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© 1987 Springer-Verlag Berlin Heidelberg

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Lütjen-Drecoll, E., Tamm, E. (1987). Differences in the Amount of ‘Plaque-Material’ in the Outflow System of Eyes with Chronic Simple and Exfoliation Glaucoma. In: Krieglstein, G.K. (eds) Glaucoma Update III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71785-7_2

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  • DOI: https://doi.org/10.1007/978-3-642-71785-7_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17399-1

  • Online ISBN: 978-3-642-71785-7

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