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Bone Marrow Transplantation for Thalassemia Major: The Place of Irradiation

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Radiology of Thalassemia
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Abstract

Standard treatment of thalassemia involves frequent blood transfusions to correct anemia and suppress marrow hyperactivity. Chronic iron chelation reduces or prevents hemosiderosis caused by this form of therapy. With this conventional treatment, life expectancy may exceed more than 25 years, and many patients manage to maintain normal activity and, occasionally, to raise families.

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References

  1. Thomas ED, Buckner CD, Sanders JE et al. (1982) Marrow transplantation for talassemia. Lancet ii: 227–229

    Google Scholar 

  2. Lucarelli G, Izzi T, Polchi P. et al. (1983) Trapianto di midollo osseo nella talassemia. Trans-fus Sangue 1: 62–64

    Google Scholar 

  3. Lucarelli G. Galimberti M, Polchi P. et al (1986) Marrow transplantation in patients with advanced thalassemia. Blood 68: 275

    Google Scholar 

  4. Lucarelli G, Polchi P, Galimberti M, et al. (1987) Bone marrow transplantation in thalassemia. In: Sirchia G, Zanella A (eds) Thalassemia today, the Mediterranean experience. Milan

    Google Scholar 

  5. Clift RA, Hansen JA, Thomas ED et al. (1979) Marrow transplantation from donors other than HLA-identical silbings. Transplantation 28: 235–242

    Article  PubMed  CAS  Google Scholar 

  6. Slavin S and EA Rachmilewitz (1986) Bone marrow transplantation in thalassemia. Bone Marrow Transplant 1: 11–15

    PubMed  CAS  Google Scholar 

  7. Lucarelli G, Polchi P, Galiberti M et al. (1985) Marrow transplantation for thalassemia following Busulphan and cyclophosphamide. Lancet ii: 1355–1357

    Article  Google Scholar 

  8. O’Reilly RJ, Brochstein J, Dinsmore R, Kirkpatrick D (1984) Marrow transplantation for congenital disorders. Semin Hematol 21: 188–221

    PubMed  Google Scholar 

  9. Lucarelli G, Polchi P, Izzi T, et al. (1984). Allogeneic marrow transplantation for thalassemia. Exp Hematol 12: 676

    PubMed  CAS  Google Scholar 

  10. Lin KH, Lin KS, Feig SA (1986). Marrow transplantation for thalassemia, Bone Marrow Transplantation 1: 115–120

    PubMed  CAS  Google Scholar 

  11. Girolamo G, de Bartolomeo P, Angrilli F et al. (1987). Bone marrow transplantation for refractory anaemia and congenital haemopathies (thalassemias, chronic granulomatous disease, Fanconi’s disease). XIII annual meeting of the EBMT Interlaken, Switzerland, 1–5 March 1987 (Abstr 43).

    Google Scholar 

  12. Anonymous (1981) Community control of hereditary anaemias (Memorandum). Bull WHO, 61: 63

    Google Scholar 

  13. Thomas ED (1985) Marrow transplantation for non malignant disorders. N Engl Med 312: 46–47

    Article  CAS  Google Scholar 

  14. Sullivan MK, Joachim-Deeg H, Sanders EJ et al (1984). Late complications after marrow transplantation. Semin Hematol 21: 1

    Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Rombos, Y. (1989). Bone Marrow Transplantation for Thalassemia Major: The Place of Irradiation. In: Papavasiliou, C., Cambouris, T., Fessas, P. (eds) Radiology of Thalassemia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72587-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-72587-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72589-0

  • Online ISBN: 978-3-642-72587-6

  • eBook Packages: Springer Book Archive

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