Skip to main content

Immunosemiotics: Whither the Immune Response? Factors Directing the Response to Humoral or Cell-Mediated Immunity

  • Conference paper
The Semiotics of Cellular Communication in the Immune System

Part of the book series: NATO ASI Series ((ASIH,volume 23))

  • 116 Accesses

Abstract

The effector phase of an immune response is commonly described as being either humoral or cell-mediated. The pathological consequences of an immune response are largely determined by the nature of the effector pathway followed. However, the factors that determine which effector mode is activated are not understood. As this represents a major choice made by the immune system, and as the result of the choice has biological and theoretical consequences, studies in my laboratory have been addressing this issue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kim, J.A., A. Woods, E. Becker-Dunn and K. Bottomly. 1985. Distinct functional phenotypes of cloned la-restricted helper T cells. J. Exp. Med. 162:188.

    Article  PubMed  CAS  Google Scholar 

  2. Hosmann, T.R., H. Cherwinski, M.W. Bond, M.A. Giedin, and R.L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activités and secreted proteins. J. Immunol 136:2340.

    Google Scholar 

  3. Spickett, G.P., M.R. Brandon, D.W. Mason, A.F. Williams and G.R. Woollett. 1983. MRC 0x22: a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen J. Exp. Med. 158:795.

    Google Scholar 

  4. Reinherz, E.L., C. Morimoto, K.A. Fitzerald, R.E. Hussey, J.F. Daley and S.F. Schlossman. 1982. Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delinates two functional subpopulations. J. Immunol. 128:463.

    PubMed  CAS  Google Scholar 

  5. Lichtman, A.H., E.A. Kurt-Jones, and A. Abbas. B cell stimulatory factor 1 and not interleukin 2 is the autocrine grown factor for some helper T lymphocytes. Proc. Nat. Acad. Sci. USA., In press.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Bottomly, K. (1988). Immunosemiotics: Whither the Immune Response? Factors Directing the Response to Humoral or Cell-Mediated Immunity. In: Sercarz, E.E., Celada, F., Mitchison, N.A., Tada, T. (eds) The Semiotics of Cellular Communication in the Immune System. NATO ASI Series, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73145-7_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73145-7_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73147-1

  • Online ISBN: 978-3-642-73145-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics