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Regulation of the Cellular Immune Response and Interaction with the Endothelium by Changes in Membrane Receptors

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New Aspects on Respiratory Failure

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Abstract

Combined with other organ failures, adult respiratory distress syndrome (ARDS) is still regarded as one of the most serious and most challenging problems of intensive care. Despite considerable therapeutical interventions, ARDS often proceeds to lung failure or contributes to the development of multiorgan failure. ARDS is characterized by an increased permeability of the lung endothelium and by changes in the lung vascular tonus, leading to impairments in gas exchange and in the microcirculation [6, 22, 24]. However, we still do not know the exact sequence of events eliciting this uniform response of the lung after a challenge by a variety of different primary diseases, e.g., sepsis, trauma, pancreatitis, or multiple transfusions.

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Authors
  1. K. Tschaikowsky
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  2. M. Georgieff
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Editors and Affiliations

  1. Institut für Anaesthesiologie, Universität Erlangen-Nürnberg, Krankenhausstrasse 12, D-8520, Erlangen, Germany

    Erich Rügheimer

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© 1992 Springer-Verlag Berlin Heidelberg

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Tschaikowsky, K., Georgieff, M. (1992). Regulation of the Cellular Immune Response and Interaction with the Endothelium by Changes in Membrane Receptors. In: Rügheimer, E. (eds) New Aspects on Respiratory Failure. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74943-8_2

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  • DOI: https://doi.org/10.1007/978-3-642-74943-8_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74945-2

  • Online ISBN: 978-3-642-74943-8

  • eBook Packages: Springer Book Archive

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