Skip to main content
SpringerLink
Log in

Sekundäre Immundefekte

  • Chapter
Diagnostische Hämatologie

  • 61 Accesses

Zusammenfassung

Gehäuftes Auftreten, schwere oder abnorme Verläufe von Infektionskrankheiten erwecken üblicherweise den Verdacht auf das Vorliegen eines Immundefekts. Die Diagnostik von Abwehrdefekten setzt daher Kenntnisse der normalen Immunantwort auf unterschiedliche mikrobielle Erreger und die Bedeutung verschiedener Effektormechanismen der Immunabwehr voraus (Tabelle 16.1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Andersen B, Goldsmith GH, Spagnuolo PI et al (1988) Neutrophil adhesive dysfunction in diabetes mellitus: the role of cellular and plasma factors. 1 Lab Clin Med 111:275–278

    CAS  Google Scholar 

  2. Ames ED, Conjalka MS, Goldberg AF, Hirschmann R, lain S, Distenfeld A, Metroka CE (1991) Hodgkin’s disease and AIDS. Twentythree cases and a review of the literature. Hematol Oncol Clin North Am 5:343–356

    PubMed  CAS  Google Scholar 

  3. Balachandran N, Oba DE, Hutt-Fletcher LM (1987) Antigenic cross-reactions among Herpes-simplex virus type 1 and 2, Epstein-Barr virus and cytomegalovirus. 1 Virol 61: 1125: 1135

    Google Scholar 

  4. Barre-Sinoussi F, Cherman lC, Rey F, Nugeyre MT, Chamoret S, Grust 1, Daugnet C, Axler-Blin C, Vezinet-Brun F, Rouzioux C, Rozenbaum W, Montagnier L (1983) Isolation of lymphotropic retrovirus from a patient at risk for acquired immunodeficiency syndrome (AIDS). Science 220:868–871

    PubMed  CAS  Google Scholar 

  5. Bart KJ, Herrmann KL (1984) Rubella in pregnancy. In: Amsley M (hrsg). Grune & Stratton Inc, New York London

    Google Scholar 

  6. Baynes RD, Bothwell TH (1990) Iron deficiency. Annu Rev Nutr 10:133–148

    PubMed  CAS  Google Scholar 

  7. Beshihan B, Hughes GRV (1979) A prospective analysis of cold reactive lymphocytotoxic antibodies in systemic lupus erythematosus. 1 Clin Path 32 (Suppl): 112–117

    Google Scholar 

  8. Bjoerkholm M, Holm G, de Faire U et al (1977) Immunological defects in healthy twin siblings to patients with Hodgkin’s disease. Scan 1 HaematoI19:396–404

    Google Scholar 

  9. Bjoerkholm M, Holm G, Mellstedt H (1978) Immunological family studies in Hodgkin’s disease. Is the immunodeficiency horizontally transmitted? Scand 1 Haematol 20:297–305

    Google Scholar 

  10. Bjornson BH, McIntyre AP, Harvey 1M, Tauber AI (1986) Studies on the effects of trimethoprim and sulfomethoxazole on human granulopoiesis. Am J Hematol 23:1–7

    Google Scholar 

  11. Bloch KJ, Buchanan WW, Wohl MS, Bunim 11 (1975) Sjoegren syndrome. A clinical, pathological and serological study of sixty-two cases. J chron Dis 44: 187–194

    Google Scholar 

  12. Bodey GP, Buckley M, Sathe YS et al (1966) Quantitative relationship between circulating leukocytes and infection in patients with acute leukemia. Ann Int Med 64:328–340

    PubMed  CAS  Google Scholar 

  13. Bovi PD, Curatola AM, Kern FG, Greco A, Ittman M, Basilico C (1987) An oncogene isolated by transfection of Kaposi’s sarcoma DNA encodes a growth factor that is a member of the FGF family. Cell 50:729–737

    CAS  Google Scholar 

  14. Carlo-Stella C, Ganser A, Hoelzer D (1987) Defective in vitro growth of the hemopoietic progenitor cells in the acquired immunodeficiency syndrome. J Clin Invest 80:286–293

    Google Scholar 

  15. Castella A, Croxson TS, Mildvan D, Witt DH, Zalusky R (1985) The bone marrow in AIDS. A histologic, hematologic and microbiologic study. Am J Clin Pathol 84:425–432

    PubMed  CAS  Google Scholar 

  16. Chandra RK, Teipar S (1983) Diet and immunocompetence. Int J Pharmac 3:175–180

    Google Scholar 

  17. Clanton DJ, Jariwalla RJ, Kress C (1983) Neoplastic transformation by a cloned human cytomegalovirus DNA fragment uniquely homologous to one of the transforming regions of herpes simplex virus type 2. Proc Natl Acad Sci USA 80:3826–3830

    PubMed  CAS  Google Scholar 

  18. Collier AC, Meyers JD, Corex L, Murphy VL, Roberts PL, Handsfield HH (1987) Cytomegalovirus infection in homosexual men. Am J Med 82:593–606

    PubMed  CAS  Google Scholar 

  19. Cozzolino S, Torcia M, Grossino AM et al (1987) Characterization of cells from invaded lymph nodes in patients with solid tumors. J Exp Med 166:303–318

    PubMed  CAS  Google Scholar 

  20. Cremer NE, Cossen CK, Shell GR, Pereira L (1985) Antibody response to cytomegalovirus polypeptides captured by monoclonal antibodies on the solid phase in enzyme immunoassays. J Clin Microbiol 21:517–521

    PubMed  CAS  Google Scholar 

  21. Csermely P, Szamel M, Resch K, Somogyi J (1988) Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes. J BioI Chern 263:6487–6490

    CAS  Google Scholar 

  22. Cupps TR, Fauci AS (1982) Corticosteroid-mediated immunoregulation in man. Immunol Rev 65:133–165

    PubMed  CAS  Google Scholar 

  23. Daling JR, Weiss NS, Klopfenstein LL (1982) Correlates of homosexual behavior and the incidence of anal cancer. JAMA 247:1988–1994

    PubMed  CAS  Google Scholar 

  24. Deitch AJ, Ma WJ, Ma L et al (1989) Endotoxin-induced bacterial translocation: a study of mechanisms. Surgery 106:293–300

    Google Scholar 

  25. Donahue RE, Johnson MM, Zon LI, Clark SC, Groopman JE (1987) Suppression of in vitro hematopoiesis following human immunodeficiency virus infection. Nature 326:200–203

    PubMed  CAS  Google Scholar 

  26. Dupont E (1988) Immunological actions of corticosteroids and cyclosporine A. Cuff Opin Immunol 1:253–256

    CAS  Google Scholar 

  27. Fauci AS, Macher AM, Longo DL, Lane HC, Rook AH, Masur H, Gelman EP (1984) Acquired immunodeficiency syndrome: epidemiologic, clinical, immunological and therapeutic considerations. Ann Int Med 100:92–106

    PubMed  CAS  Google Scholar 

  28. Fauci A, Masur H, Gelman EP, Markham PD, Hahn BH, Lane HC (1985) The acquired immunodeficiency syndrome. Ann Int Med 102:800–813

    PubMed  CAS  Google Scholar 

  29. Fauci AS (1988) The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. Science 239:617–622

    PubMed  CAS  Google Scholar 

  30. Feldmeier H, Gastl GA, Poggensee U et al (1985) Relationship between intensity of infection and immunomodulation in human schistosomiasis. I. Lymphocyte subpopulations and specific antibody responses. Clin Exp Immunol 60:225–332

    PubMed  CAS  Google Scholar 

  31. Flynn A, Loftus MA, Finke JH (1984) Production of interleukin-1 and interleukin-2 in allogeneic mixed lymphocyte cultures under copper, magnesium and zinc deficient conditions. Nutr Res 4:673–679

    CAS  Google Scholar 

  32. Foon KA, Rai KR, Gale RP (1990) Chronic lymphocytic leukemia: New insights in biology and therapy. Ann Int Med 113:525–539

    PubMed  CAS  Google Scholar 

  33. Friedland GH, Klein RS (1987) Transmission of the human immunodeficiency virus. N Engl J Med 317:1125–1135

    PubMed  CAS  Google Scholar 

  34. Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel RA (1986) Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann NeuroI20:289–295

    Google Scholar 

  35. Gärtner L, Oberender H, Straube E, Czienek R (1986) Zur Bewertung IgMAntikorper positiver Zytomegalie-Virus positiver Befunde. Z Klin Med 21: 1763–1766

    Google Scholar 

  36. Gallo RC, Salahuddin SZ, Popovic M (1984) Frequent detection and isolation of cytopathic retrovirus (HTLV-III) from patients with AIDS and pre-AIDS. Science 224:500–504

    PubMed  CAS  Google Scholar 

  37. Ganser A, Carlo-Stella C, Völkers B, Brodt KH, Helm EB, Hoelzer D (1987) Loss of hematopoietic progenitor cells CFU-GEMM, BFU-E, CFU-Mk, and CFU-GM in the acquired immunodeficiency syndrome (AIDS)? In: Neth R, Gallo RC, Greaves MF, Kabisch H (eds) Modern trends in human leukemia VII. Springer, Berlin Heidelberg New York, p 175–176

    Google Scholar 

  38. Ganser A (1988) Abnormalities of hematopoesis in the acquired immunodeficiency syndrome. Blut 56:49–53

    PubMed  CAS  Google Scholar 

  39. Gartner S, Markovits P, Markovits DM, Kaplan MH, Gallo RC, Popovic M (1986) The role of mononuclear phagocytes in HTLV-IIIILAV infection. Science 233:215–219

    PubMed  CAS  Google Scholar 

  40. Gelford EW, Cheng RK, Mills GB (1987) The cyclosporins inhibit lymphocyte activation on more than one site. J Immunol138:1115–1120

    Google Scholar 

  41. Gelman EP (1985) New concepts in Kaposi’s sarcoma. The acquired immunodeficiency syndrome. An update. Ann Int Med 102:800–813

    Google Scholar 

  42. Genoglio CM, McDougall JK (1984) The relationship of cytomegalovirus to Kaposi’s sarcoma. In: Friedman-Kien AE, Laubenstein LS (eds) AIDS. The epidemic of Kaposi’s sarcoma and opportunistic infections. Masson Publishing USA, New York, pp 329–336

    Google Scholar 

  43. Germain RN (1988) Antigenprocessing and CD4+ T cell depletion in AIDS. Cell 54:441–444

    PubMed  CAS  Google Scholar 

  44. Gilstrap LC, Faro S (1990) Infections in pregnancy. Alan R Liss Inc, New York

    Google Scholar 

  45. Gottlieb MS, Groopman JE, Weinstein WM, Fahey JL, Detels R (1983) The acquired immunodeficiency syndrome. Ann Int Med 99:208–220

    PubMed  CAS  Google Scholar 

  46. Goudsmit J, Wolters EC, Bakkar M (1986) Intrathecal synthesis of antibodies to HTLV-III in patients with AIDS or AIDS-related complex. Br Med J 292:1231–1234

    CAS  Google Scholar 

  47. Greene WC (1990) Regulation of HIV-1 gene expression. Annu Rev Immunol 8:453–475

    PubMed  CAS  Google Scholar 

  48. Greenspan D, Greenspan JS, Conant M (1984) Oral “hairy” leukoplakia in male homosexuals: evidence of association with both papillomavirus and a herpes-group virus. Lancet ii:831–834

    Google Scholar 

  49. Greenspan JS, Greenspan D, Lenette ET (1985) Replication of Epstein-Barr virus within the epithelial cells of a oral ”hairy” leukoplakia, an AIDS-associated lesion. N Engl J Med 313:1564–1571

    PubMed  CAS  Google Scholar 

  50. Groopman JE, Sullivan JL, Mulder C, Ginsburg D, Orkin SH, O’Hara CJ, Fa1chuk K, Wong-Staal F, Gallo RC (1986) Pathogenesis of B cell lymphoma in a patient with AIDS. Blood 67:612–615

    PubMed  CAS  Google Scholar 

  51. Guillou PJ, Sedman PC, Ramsden CW (1989) Inhibition of lymphokine-activated killer cell generation by cultured tumor cell lines in vitro. Cancer Immunol Immunother 28:43–53

    PubMed  CAS  Google Scholar 

  52. Gyorky F, Sinkowics JG, Melnick JL (1984) Retroviruses in Kaposi-sarcoma cells in AIDS (letter). N Engl J Med 311:1183–1184

    Google Scholar 

  53. Harper ME, Marselle LM, Gallo RC, Wong-Staal F (1986) Detection of lymphocytes expressing human T-lymphotropic virus type III in lymphnodes and peripheral blood from infected individuals by in situ hybridization. Proc Nat! Acad Sci USA 83:772–777

    CAS  Google Scholar 

  54. Heagy W, Kelley VB, Strom TB, Mayer K, Shapiro HM, Mandel R, Finberg R (1984) Decreased expression of HLA class II antigens on monocytes of patients with acquired immunodeficiency syndrome. J Clin Invest 74:2089–2096

    PubMed  CAS  Google Scholar 

  55. Heber D (1990) Cancer and malnutrition. In: Morley JE, Glick Z, Rubenstein LZ (eds) Geriatric nutrition. Raven Press Ltd, New York

    Google Scholar 

  56. Ho DD, Rota TR, Hirsch MS (1986) Infection of monocyte/macrophages by human T lymphotropic virus type III. J Clin Invest 77: 1712–1715

    PubMed  CAS  Google Scholar 

  57. Ho DD, Pomerantz JC, Kaplan JC (1987) Pathogenesis of infection with human immunodeficiency virus. N Engl J Med 317:278–286

    PubMed  CAS  Google Scholar 

  58. Hobbs JR (1968) Secondary antibody deficiency. Proc R Soc Med 61:883–889

    PubMed  CAS  Google Scholar 

  59. Holzman RS, Walsh CM, Karpatkin S (1987) Risk for the acquired immunodeficiency syndrome among thrombocytopenic and nonthrombocytopenic homosexual men seropositive for the human immunodeficiency virus. Ann Int Med 106:383–386

    PubMed  CAS  Google Scholar 

  60. Hughes GRV (1982) Systemic lupus erythematosus. In: Lachman PJ, Peters DK (eds) Clinical aspects of immunology. 4. Ausgabe, Band II, pp 1196–1216

    Google Scholar 

  61. Ioachim HL, Cooper MC, Hellman GC (1985) Lymphomas in men at high risk for acquired immune deficiency syndrome (AIDS). A study of 21 cases. Cancer 56:2831–2842

    PubMed  CAS  Google Scholar 

  62. Jahn G, Mach M, Fleckenstein B (1988) Cytomegalievirus and AIDS. AIFO 2:59–72

    Google Scholar 

  63. Joller-Jemelka HI, Vogt M, Joller PW (1985) Immunologische Untersuchungen bei Patienten mit erworbenem Immunmangel-Syndrom (AIDS) und bei AIDS-Verdacht. Schweiz Med Wschr 115:125–132

    PubMed  CAS  Google Scholar 

  64. Joncas JH (1985) Viral mechanisms of immunosuppression: Cells of the immune system as targets for viral infection and feedback inhibition by suppressor cells and immunoglobulins. In: Gilmore N, Weinberg MA (eds) Alan R Liss Inc, New York, pp 265–271

    Google Scholar 

  65. Kahan BD (1989) Cyclosporine. N Engl J Med 321:1725–1738

    CAS  Google Scholar 

  66. Kaplan MR, Susin M, Pahwa SG, Fetten J, Allen SL, Lichtman S, Sarngadharan MG, Gallo RC (1987) Neoplastic complications of HTLV-III infection. Lymphomas and solid tumors. Am J Med 82:389–393

    PubMed  CAS  Google Scholar 

  67. Kay NE (1981) Abnormal T-cell subpopulation function in chronic lymphocytic leukemia: excessive suppressor (T) and deficient helper (T) activity in respect to B-cell proliferation. Blood 57:418–420

    PubMed  CAS  Google Scholar 

  68. Kay NE, Oken MM, Perry RT (1983) The influential T cell in B cell neoplasms. J Clin Onco18:810–816

    Google Scholar 

  69. Knowles DM, Chamulak GA, Subar M, Burke SJ, Dugan M, Wernz J, Slywotzky C, Pelicci PG, Dalla-Favera R, Raphael B (1988) Lymphoid neoplasia associated with the acquired immunodeficiency syndrome. Ann Int Med 108:744–753

    PubMed  CAS  Google Scholar 

  70. Koenig S, Gendelman HE, Orenstein JM (1986) Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233:1089–1093

    PubMed  CAS  Google Scholar 

  71. Kroegel C, Hess G, Meyer zu Btischenfelde KH (1988) Infection with the human immunodeficiency virus (HIV): a comparison of different classifications. AIFO 1:17–23

    Google Scholar 

  72. Krüger GRF (1986) Klinische Pathologie bei AIDS-Patienten und bei AIDS Risikopersonen (Teil3). AIFO 4:195–202

    Google Scholar 

  73. Krüger GRF, Rowert J (1988) Klinische Immunpathologie der Zytomegalievirus (CMV)-Infektion. AIFO 5:243–257

    Google Scholar 

  74. 7la. Kulkosky J, Skalka AM (1990) HIV DNA integration: observations and interferences. J Acquir Immune Defic Syndr 3:839–851

    Google Scholar 

  75. Kumar RK, Penny R (1982) Cell-mediated immunodeficiency in Hodgkin’s disease. Immunology Today 3:269–273

    Google Scholar 

  76. Lane HC, Depper JM, Warner GG, Whalen GBS, Waldmann TA, Fauci AS (1984) Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med 313:79–84

    Google Scholar 

  77. Lane HC, Fauci AS (1985) Immunologic abnormalities in the acquired immunodeficiency syndrome. Ann Rev Immunol 3:477–500

    CAS  Google Scholar 

  78. Lazarus HM, Creger RJ, Gerson SL (1989) Infectious emergencies in oncology. Sem Oncol 16:543–560

    CAS  Google Scholar 

  79. Lee MR, Ho DD, Gurney ME (1987) Functional interaction and partial homology between human immunodeficiency virus and neuroleukin. Science 237:1047–1100

    PubMed  CAS  Google Scholar 

  80. Leen CL (1990) Zinc deficiency and immune function. Ann Rev Nutr 10:415–431

    Google Scholar 

  81. Leiderman IZ, Greenberg ML, Adelsberg BR, Siegal FP (1984) Defective myelopoiesis in acquired immunodeficiency syndrome (AIDS). In: Gottlieb MS, Groopman JE (eds) Acquired immunodeficiency syndrome. Alan R Liss, New York, pp 281–289

    Google Scholar 

  82. Lenette EH et al (1985) Manual of Clinical Microbiology. American Society of Microbiology, Washington DC

    Google Scholar 

  83. Levine AM (1991) Epidemiology, clinical characteristics, and management of AIDSrelated lymphoma. Hematol Oncol Clin North Am 5:331–342

    PubMed  CAS  Google Scholar 

  84. Löning T, Milde K, Foss HD (1986) In situ hybridization for the detection of cytomegalovirus (CMV) infection. Virch Archiv 409:777–790

    Google Scholar 

  85. Luft BJ, Brooks RG, Conley FK, McCabe RE, Remington JS (1984) Toxoplasmic encephalitis in patients with acquired immune deficiency syndrome. JAMA 252:913–917

    PubMed  CAS  Google Scholar 

  86. Ma P, Villanueva TG, Kaufmann D, Gillooley JF (1984) Respiratory cryptosporidiosis in the acquired immune deficiency syndrome. Use of modified cold kiyoun and hemacolor stains for rapid diagnosis. JAMA 252:1298–1301

    PubMed  CAS  Google Scholar 

  87. Martin J (1984) Acquired immunodeficiency syndrome (AIDS) and Kaposi’s sarcoma. Int J Dermatol 23: 483–486

    PubMed  CAS  Google Scholar 

  88. McDougal JS, Kennedy MS, Sligh JM, Cort SP, Mawle A, Nicholson JKA (1986) Binding of HTL V-IIIILAV to T4+ T-cell by a complex of the 110K viral protein and the T4 molecule. Science 231:382–385

    PubMed  CAS  Google Scholar 

  89. McGowan IE (1991) Infections in diabetes mellitus. In: Davidson JK (eds) Clinical diabetes mellitus. 2. Auflage. Georg Thieme-Verlag, Stuttgart New York, pp 656–666

    Google Scholar 

  90. Middeldorp JM, Jongsma J, ter Haar A, Schirm J, The HT (1984) Detection of immunoglobulin M and G antibodies against cytomegalovirus early and late antigens by enzyme-linked immunosorbent assay. J Clin MicrobioI20:763–771

    Google Scholar 

  91. Mitsuyasu RT, Groopman (1984) Biology and therapy of Kaposi’s sarcoma. Sem Oncol 11:53–67

    CAS  Google Scholar 

  92. Morfeldt-Manson J. Julander I von Stedingk LV, Wasserman J, Nilsson B (1988) Elevated serum beta-2 microglobulin-a prognostic marker for development of AIDS among patients with persistent generalized lymphadenopathy. Infection 16: 109–110

    Google Scholar 

  93. Morris L, Distenfeld A, Amorosi E, Karpatkin S (1982) Autoimmune thrombocytopenic purpura in homosexual men. Ann Int Med 96:714–717

    PubMed  CAS  Google Scholar 

  94. Moynahan EJ (1981) Acrodermatitis enteropathica and the immunological role of zinc. Immunodermatology 30:437–447

    Google Scholar 

  95. Murdoch IA (1990) Continued need for pneumococcal prophylaxis after splenectomy. Arch Dis Child 66: 1268–1269

    Google Scholar 

  96. Murphy MF, Metcalf P, Waters AH, Linch DC, Chingsong-Popov R, Carne C, Weller IV (1985) Immune neutropenia in homosexual men (letter). Lancet i:217–218

    Google Scholar 

  97. Nelson JA, Fleckenstein B, Galloway DA (1982) Transformation of NIH3T3 cells with cloned fragments of human cytomegalovirus strain AD 169. J ViroI43:83–91

    Google Scholar 

  98. Osborne BM, Guarda LA, Butler II (1984) Bone marrow biopsies in patients with the acquired immunodeficiency syndrome. Hum Pathol 15: 1048–1053

    PubMed  CAS  Google Scholar 

  99. Pelicci PG, Knowles DM, Arlin ZA (1986) Multiple monoclonal B-cell expansions and c-myc oncogene rearrangements in AIDS-related lymphoproliferative disorders: implications for lymphomagenesis. J Exp Med 164:2049–2060

    PubMed  CAS  Google Scholar 

  100. Pelton BK, Hylton W, Denman A (1982) Selective immunotuppressive effects of measles virus infection. Clin Exp Immunol 47: 19–26

    PubMed  CAS  Google Scholar 

  101. Penneys NS, Hick B (1985) Unusual cutaneous lesions associated with acquired immunodeficiency syndrome. JAm Acad Dermatol13:845–852

    Google Scholar 

  102. Popovic M, Sarngadharan MG, Read E, Gallo RC (1984) Detection, isolation, and continuous production of a cytopathic retrovirus (HTLV-III) from patients with AIDS and pre-AIDS. Science 224:497–500

    PubMed  CAS  Google Scholar 

  103. Preac-Mursic V (1988) Mikrobiologische Diagnostik von sogenannten “atypischen Mykobakterien”. AIFO 1:32–34

    Google Scholar 

  104. Prior E, Goldberg AF, Conjalka MS, Chapman WE, Tay S, Ames ED (1986) Hodgkin’s disease in homosexual men: an AIDS-related phenomenon. Am J Med 81:1085–1088

    PubMed  CAS  Google Scholar 

  105. Rabson AB, Martin MA (1985) Molecular organisation of the AIDS virus. Cell 40:477–480

    PubMed  CAS  Google Scholar 

  106. Redfield RR, Wright DC, Tramont ED (1986) The Walter Reed staging classification for HTLV-IIIILAV infection. N Engl 1 Med 314:131–132

    CAS  Google Scholar 

  107. Reinherz EL, O’Brien C, Rosenthal P, Schlossman SF (1980) The cellular basis for viral-induced immunodeficiency: Analysis by monoclonal antibodies. 1 Immunol 175:1269–1276

    Google Scholar 

  108. Resnick L, di Marzo-Veronese F, Schupbach 1 (1985) Intra-blood-brain barrier synthesis of HTLV-III specific IgG in patients with neurologic symptoms associated with AIDS or AIDS-related complex. N Engl 1 Med 313:1498–1504

    PubMed  CAS  Google Scholar 

  109. Revillard IP (1990) Iatrogenic immunodeficiencies. Curr Opin Immunol 2:445- 450

    Google Scholar 

  110. Rodrick ML, Wood 11, O’Mahony JB et al (1986) Mechanisms of immunosuppression associated with severe non-thermal traumatic injuries in man: production of interleukin-1 and 2. J Clin Immunol 6: 130–138

    Google Scholar 

  111. Romagnani S, Del Prete GF, Maggi E et al (1983) Displacement of T lymphocytes with the “helper/inducer” phenotype from peripheral blood to lymphoid organs in untreated patients with Hodgkin’s disease. Scand 1 Haematol 22:136–142

    Google Scholar 

  112. Romagnani S, Ferrini PL, Ricci M (1985) The immune derangement in Hodgkin’s disease. Sem Hematol 22:41–55

    CAS  Google Scholar 

  113. Rustagi P, Han T, Ziolkowski L et al (1983) Anti-granulocyte antibodies in chronic lymphocytic leukemia and other lymphoproliferative disorders. Blood 62 (SuppI): 106A (Abstrakt)

    Google Scholar 

  114. Sagaster P (1990) Ernährung und Immunitat. In: Dostal V, Bayer W, Schleicher P, Schmidt KH (Hrsg) Immunomonitoring und additive Immuntherapie. Hippokrates Verlag, Stuttgart, pp 103–110

    Google Scholar 

  115. Sattentau QJ, Weiss RA (1988) The CD4 antigen: physiological ligand and HIV receptor. Cell 52:631–633

    PubMed  CAS  Google Scholar 

  116. Schneider DR, Picker U (1985) Myelodysplasia in the acquired immune deficiency syndrome. Am J Clin Pathol 84:144–152

    Google Scholar 

  117. Shearer WT, Ritz J, Finegold M (1985) Epstein-Barr virus associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency. N Engl J Med 312: 1152–1159

    Google Scholar 

  118. Shumak KH, Rock GA (1984) Therapeutic plasma exchange. N Engl J Med 310:762–771

    PubMed  CAS  Google Scholar 

  119. Smith PD, Ohura K, Masur H, Lance HC, Fauci AS, Wahl SM (1984) Monocyte function in the acquired immune deficiency syndrome: defective chemotaxis. J Clin Invest 74:2121–2128

    PubMed  CAS  Google Scholar 

  120. Soave R (1986) The immunocompromised host. Part II: Acquired immune deficiency syndrome. In: Reese RE, Douglas RG (eds) A practical approach to infectious diseases. Little, Brown & Company, Boston Toronto, pp 527–544

    Google Scholar 

  121. Solomkin IS (1990) Neutrophil disorders in burn injury: complement, cytokines, and organ injury. 1 Trauma 30 (Suppl):S80–5

    CAS  Google Scholar 

  122. Specter S, Bendinelli M, Friedman H (1988) Virus-induced immunosuppression. Plenum Press, New York London

    Google Scholar 

  123. Spectors S, Lancz Gl (1986) Clinical Virology Manual. Elsevier, New York

    Google Scholar 

  124. Spivak lL, Bender BS, Quinn TC (1984) Hematologic abnormalities in the acquired immune deficiency syndrome. Am 1 Med 77:224–228

    CAS  Google Scholar 

  125. Stingl G, Rappersberger K, Tschachler E, Gartner S, Groh V, Mann DL, Wolff K, Popovic M (1990) Langerhans cells in HIV-l infection. J Am Acad Dermatol 22: 1210: 1217

    Google Scholar 

  126. Stricker RB, Abrams DI, Corash L, Shuman MA (1985) Target platelet antigen in homosexual men with immune thrombocytopenia. N Engl J Med 313:1375–1380

    PubMed  CAS  Google Scholar 

  127. Subar M, Knowles DM, Dalla-Favera R (1987) AIDS-associated lymphomas: a molecular analysis of 16 cases. Blood 70 (Suppl 1): 128A

    Google Scholar 

  128. Szabados A (1988) Die Pneumocystis carinii-Diagnostik bei AIDS – diagnostische Besonderheiten, neue Erkenntnisse über den Erreger. AIFO 1:34–41

    Google Scholar 

  129. Szentivanyi, Friedman (1986) Viruses, immunity, and immunodeficiency. Plenum, New York

    Google Scholar 

  130. Terragna A, Dodi F, Anselmo M, Del Bono V (1986) The Walter Reed staging classification in the follow-up of HIV infection. N Engl J Med 315: 1355–1356

    PubMed  CAS  Google Scholar 

  131. Treacy M, Lai L, Costello C, Clark A (1987) Peripheral blood and bone marrow abnormalities in patients with HIV related disease. Br J Haematol 65:289–294

    PubMed  CAS  Google Scholar 

  132. Unger PD, Strauchen JA (1986) Hodgkin’s disease in AIDS complex patients: report of four cases and tissue immunologic marker studies. Cancer 58:821–825

    PubMed  CAS  Google Scholar 

  133. Vadhan-Raj S, Wong G, Gnecco C, Cunningham-Rundles S, Krim M, Real FX, Oettgen HF, Krown SE (1986) Immunologic variables as predictors of prognosis in patients with Kaposi’s sarcoma and the acquired immunodeficiency syndrome. Cancer Res 46:417–425

    PubMed  CAS  Google Scholar 

  134. Vanky F, Peterffy A, Book S et al (1983) Correlation between lymphocyte-mediated anti-tumor reactivities and the clinical course. II. Evaluation of 69 patients with lung carcinoma. Cancer Immunol Immunotherap 16: 17–22

    CAS  Google Scholar 

  135. Volberding P (1984) Therapy of Kaposi’s sarcoma in AIDS. Sem Oncol11:60–67

    Google Scholar 

  136. Vose BM, Moore M (1985) Human tumor-infiltrating lymphocytes. A marker of host response. Sem Hematol 22:27–40

    CAS  Google Scholar 

  137. Wain-Hobson S, Sonigo P, Danos 0, Cole S, Alizon M (1985) Nucleotide sequence of AIDS-virus, LAV. Cell 40:9–17

    PubMed  CAS  Google Scholar 

  138. Warner LC, Fisher BK (1986) Cutaneous manifestations of the acquired immunodeficiency syndrome. Int J Dermatol 25:337–350

    PubMed  CAS  Google Scholar 

  139. White KS, Covington D, Churchill P et al (1991) Patient awareness of health precautions after splenectomy. Am J Infect Control 19:36–41

    PubMed  CAS  Google Scholar 

  140. WHO-Report No 16 (1988) AIDS surveillance in Europe. AIFO 5:285–290

    Google Scholar 

  141. Wiley CA, Schrier RD, Nelson JA, Lampert PW, Oldstone MBA (1986) Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Nat! Acad Sci USA 83:7089–7093

    CAS  Google Scholar 

  142. Wolfe JHN, Wu AVD, O’Connor NE et al (1982) Anergy, immunosuppressive serum, and impaired lymphocyte blastogenesis in burn patients. Arch Surg 117:1266–1271

    PubMed  CAS  Google Scholar 

  143. Wong-Staal F, Gallo RC (1985) Human T-lymphotropic retroviruses. Nature 317:395–403

    PubMed  CAS  Google Scholar 

  144. Yamanaka N, Harabuchi Y, Himi T, Kataura (1988) Immunosuppressive substance in the sera of head and neck cancer patients. Cancer 62: 1293–1298

    CAS  Google Scholar 

  145. Zagrury D, Bernard J, Leonard R, Cheynier R, Feldman M, Sarin PS, Gallo RC (1986) Longterm cultures of HTLV-III infected T-cells: A model of cytopathology of T-cell depletion in AIDS. Science 231: 850–853

    Google Scholar 

  146. Ziegler JL, Beckstead JA, Volberding PA, Abrams DI, Levine AM, Lukes RJ, Gill PS, Burkes RL, Meyer PR, Metroka CE, Mouradian J, Moore A, Riggs SA, Butler JJ, Cabanillas FC, Hersh E, Newell GR, Laubenstein LJ, Knowles D, Odajnyk C, Raphael B, Koziner B, Urmacher C, Clarkson BD (1984) Non-Hodgkin’s lymphoma in 90 homosexual men. Relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome. N Engl J Med 311:565–570

    PubMed  CAS  Google Scholar 

  147. Zunich KM, Lane HC (1991)Immunologic abnormalities in HIV infection. Hematol Oncol Clin North Am 5:215–228

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. G. Gastl
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Hengster
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung für Hämatologie und Onkologie, Universitätsklinik für Innere Medizin, Anichstraße 35, A-6020, Innsbruck, Austria

    Heinz Huber

  2. II. Med. Universitätsklinik und Poliklinik, Chemnitzstraße 33, D-2300, Kiel 1, Germany

    Helmut Löffler

  3. Universitätsklinik für Innere Medizin, Anichstraße 35, A-6020, Austria, Österreich

    Dorothea Pastner

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Gastl, G., Hengster, P. (1992). Sekundäre Immundefekte. In: Huber, H., Löffler, H., Pastner, D. (eds) Diagnostische Hämatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76860-6_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-76860-6_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76861-3

  • Online ISBN: 978-3-642-76860-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation