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Photodynamic Therapy of Gastric Malignancies: Current Status and Future Prospects

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The Stomach

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Abstract

Photodynamic therapy (PDT) is a new approach to the local treatment of cancers. A photosensitizer, non-toxic in the dark, is administered to a patient. The photosensitizer is retained with some degree of selectivity by tumor tissue. On exposure to light of the appropriate wavelength, highly reactive but very short lived chemical species are produced which cause cell death. The short half life of these toxic species ensures that the cytotoxic effect is confined to the tissue exposed to the therapeutic light, thus avoiding systemic toxicity.

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Authors
  1. C. S. Loh
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  2. S. G. Bown
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Editors and Affiliations

  1. University of Münster, Albert-Schweitzer-Str. 33, D-48149, Münster, Germany

    W. Domschke MD MD(hon) FACG (Chairman of the Department of Medicine B) (Chairman of the Department of Medicine B)

  2. University of Kraków, ul. Grzegórzecka 16, PL-31531, Kraków, Poland

    S. J. Konturek MD (Chairman of the Institute of Physiology) (Chairman of the Institute of Physiology)

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© 1993 Springer-Verlag Berlin Heidelberg

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Loh, C.S., Bown, S.G. (1993). Photodynamic Therapy of Gastric Malignancies: Current Status and Future Prospects. In: Domschke, W., Konturek, S.J. (eds) The Stomach. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78176-6_29

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  • DOI: https://doi.org/10.1007/978-3-642-78176-6_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56613-7

  • Online ISBN: 978-3-642-78176-6

  • eBook Packages: Springer Book Archive

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