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Führt die Vermeidung homologer Bluttransfusionen zur Verbesserung der Prognose maligner Tumoren?

  • Conference paper
Elektive Chirurgie

Part of the book series: Innovative Aspekte der klinischen Medizin ((KLIN MED,volume 3))

  • 18 Accesses

Zusammenfassung

Burrows u. Tartter [6] berichteten 1982 erstmals über eine Verschlechterung der Prognose bei Patienten mit kolorektalen Karzinomen, die eine perioperative Bluttransfusion erhalten hatten. Sie gaben für die transfundierten Patienten eine Fünfjahresüberlebensrate von 51% vs. 84% bei den Patienten ohne Bluttransfusion an (p<0,005). Während diese Beobachtungen in den folgenden Jahren durch einige ähnliche Arbeiten gestützt wurden [4, 8, 10, 25, 27, 31, 35], kamen andere Arbeitsgruppen zu dem Ergebnis, daß der Einfluß der Bluttransfusion auf die Prognose maligner Tumoren kein eigenständiger ist, sondern lediglich Ausdruck damit assoziierter negativer Prognosefaktoren [2, 8, 9, 16, 21, 22, 30, 35, 36]. Im folgenden sollen diese Zusammenhänge näher analysiert, und generell Ansätze zur Vermeidung der Fremdbluttransfusion auch bei Patienten mit Tumorleiden erörtert werden.

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Authors
  1. P. M. Schlag
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  2. Ch. Kettelhack
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Editor information

Editors and Affiliations

  1. Institut für Anästhesiologie und Operative Intensivmedizin, Klinikum Mannheim, Teodor-Kutzer-Ufer 1, 68167, Mannheim, Deutschland

    K. van Ackern

  2. Transfusionszentrum, III. Medizinischen Universitätsklinikum, Klinikum Großhadern, Marchioninistraße 15, 81377, München, Deutschland

    W. Mempel

  3. Abteilung für Chirurgie und Chirurgische Onkologie, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin, Lindenberger Weg 80, 13122, Berlin, Deutschland

    P. Schlag

  4. Forschung Klinik, Nephrologie/Onkologie, Boehringer Mannheim GmbH, Sandhofer Straße 116, 68305, Mannheim, Deutschland

    P. Scigalla

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© 1994 Springer-Verlag Berlin Heidelberg

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Schlag, P.M., Kettelhack, C. (1994). Führt die Vermeidung homologer Bluttransfusionen zur Verbesserung der Prognose maligner Tumoren?. In: van Ackern, K., Mempel, W., Schlag, P., Scigalla, P. (eds) Elektive Chirurgie. Innovative Aspekte der klinischen Medizin, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79238-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-79238-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58388-2

  • Online ISBN: 978-3-642-79238-0

  • eBook Packages: Springer Book Archive

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