Abstract
Lesions in the peripheral and central nervous system are not seen grossly.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Allen N, Mendell JR, Billmaier DJ, Fontaine RE, O’Neill J (1975) Toxic polyneuropathy due to methyl-H-butylketone. Arch Neurol 32: 209–218
Altenkirch H, Wagner HM, Stoltenburg-Didinger G, Steppat R (1982 a) Potentiation of hexacarbon-neurotoxicity by methyl-ethyl-ketone (MEK) and other substances: clinical and experimental aspects. Neurobehav Toxicol Teratol 4: 623–627
Altenkirch H, Wagner HM, Stoltenburg-Didinger G, Spencer PS (1982 b) Nervous system responses of rats to subchronic inhalation of H-hexane and w-hexane + methyl-ethyl-ketone mixtures. J Neurol Sci 57: 209–219
DeCaprio AP, Olavos EJ, Weber P (1982) Covalent binding of a neurotoxic w-hexane metabolite. Conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione. Toxicol Appl Pharmacol 65: 440–450
Goldman JE, Yen SH (1986) Cytoskeletal protein abnormalities in neurodegenerative diseases. Ann Neurol 19: 209–223
Graham DG (1980) Hexane neuropathy: a proposal for pathogenesis of a hazard of occupational exposure and inhalant abuse. Chem Biol Interact 32: 339–345
Krasavage WJ, O’Donoghue JL, DiVincenco GD, Terhaar CJ (1980) The relative neurotoxicity of methyl-nbutyl-ketone, n-hexane and their metabolites. Toxicol Appl Pharmacol 52: 433–441
Spencer PS, Sabri MI, Schaumburg HH, Moore CL (1979) Does a defect of energy metabolism in the nerve fiber underlie axonal degeneration in polyneuropathies? Ann Neurol 5: 501–507
Spencer PS, Couri D, Schaumburg HH (1980 a) n-Hexane and methyl-H-butylketone. In: Spencer PS, Schaumburg HH (eds) Experimental and clinical neurotoxicology. Williams and Wilkins, Baltimore, pp 456–475
Spencer PS, Schaumburg HH, Sabri MI, Veronesi B (1980 b) The enlarging view of hexacarbon neurotoxicity. CRC Crit Rev Toxicol 7: 279–356
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Stoltenburg-Didinger, G., Altenkirch, H. (1988). Neurotoxic Effects of Hexacarbons (n-Hexane, Methyl-n-Butylketones; 2,5-Hexane-Dione; 1,4-Diketones). In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Nervous System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83516-2_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-83516-2_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-83518-6
Online ISBN: 978-3-642-83516-2
eBook Packages: Springer Book Archive