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Immunogenetic and Developmental Aspects of Tissue Transplantation Immunity in Urodele Amphibians

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Biology of Amphibian Tumors

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 1969))

Abstract

For the past 50 years, transplantation of tissues, organs, and their primordia in embryonic, larval, and adult urodele amphibians has been an essential tool in the continuing study of development (1), regeneration (2), and oncogenesis (3). It is only recently that systematic studies of the immunologic consequences and parameters of transplantation in these ectothermic vertebrates have been undertaken (4–9). This paper will review much of our current knowledge of transplantation immunity in this vertebrate order from the perspectives of comparative and developmental immunology and immunogenetics.

Supported by grant 5 53-4-770 from the American Cancer Society and G. R. S. G. grant FRO 5403 to the University of Rochester

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Cohen, N. (1969). Immunogenetic and Developmental Aspects of Tissue Transplantation Immunity in Urodele Amphibians. In: Mizell, M. (eds) Biology of Amphibian Tumors. Recent Results in Cancer Research, vol 1969. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85791-1_12

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  • DOI: https://doi.org/10.1007/978-3-642-85791-1_12

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