Abstract
Current advances in knowledge of mammalian immunoglobulin structure have spurred investigative efforts directed toward the development of more primitive study models. Historical observations of Metchnikoff (1) and Widal and Sicard (2) described the capacity for antibody production and its temperature dependence in amphibians. These early observations provided tire basis for recent renewed emphasis on research in this field.
Supported by Public Health Service Research Grants AI-02693 and AI-08068; Training Grants DE-7 and AI-00293.
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Legler, D.W., Evans, E.E., Weinheimer, P.F., Acton, R.T., Attleberger, M.H. (1969). Immunoglobulin and Complement Systems of Amphibian Serum. In: Mizell, M. (eds) Biology of Amphibian Tumors. Recent Results in Cancer Research, vol 1969. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85791-1_13
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DOI: https://doi.org/10.1007/978-3-642-85791-1_13
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