Stable Angina Pectoris

Abstract

Nitrates are the cornerstone in treatment of anginal episodes of all types and, in most centers, also in prevention of such episodes. The sublingual or intravenous administration of nitrates for relief of pain in patients with an acute anginal episode is universal. The use of long-acting oral nitrates, in high doses around the clock, is recommended by most, but not all, cardiologists for prevention of anginal episodes. Those concerned with tolerance use high doses at long time intervals. Others use very low doses. In a few centers nitrates are not used at all for prophylaxis but only for treatment of anginal episodes. Several studies have now been performed to resolve these questions and to standardize treatment.