Abstract
For a rational use of stress tests and an appropriate interpretation of their results, it may be useful to adopt a pathogenetic classification, taking into account the diagnostic end point of the test. Tests inducing vasospasm (ergonovine infusion and hyperventilation) explore the functional component. Tests trying to unmask coronary stenosis (exercise, dipyridamole, adenosine, dobutamine, pacing) mostly explore the ceiling of coronary reserve as defined by organic factors (Fig. 1). Some of these stressors (such as exercise) may also induce variations in coronary tone which can be superimposed onto the organic factors, thus blurring the correlation between coronary anatomy and test positivity.
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Picano, E. (2003). Pathogenetic Mechanisms of Stress. In: Stress Echocardiography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05096-5_8
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DOI: https://doi.org/10.1007/978-3-662-05096-5_8
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