Abstract
After the remarkable improvement of hemostasis in cardiopulmonary bypass (CPB) obtained with the proteinase inhibitor aprotinin [17], its use spread rapidly in cardiac clinics throughout Europe [2, 3]. Although the mode of action has not been completely revealed, we concurrently showed the relation of improved hemostasis with preserved platelet adhesive receptors [18, 19]. Increasing numbers of patients with coronary artery diseases are now treated with aspirin [14] and are submitted with this treatment for coronary artery bypass grafting operation (CABG).
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© 1991 Springer-Verlag Berlin Heidelberg
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Tabuchi, N., van Oeveren, W., Eijsman, L., Roozendaal, K.J., Gu, Y.J., Wildevuur, C.R.H. (1991). Preserved Hemostasis During the Combined Use of Aprotinin and Aspirin in CABG Operations. In: Friedel, N., Hetzer, R., Royston, D. (eds) Blood Use in Cardiac Surgery. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-06119-0_39
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DOI: https://doi.org/10.1007/978-3-662-06119-0_39
Publisher Name: Steinkopff, Heidelberg
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