Abstract
Interiors of living cells are structurally and dynamically organized by networks of protein polymers called the cytoskeleton. Of these filamentous structures microtubules are best characterized and appear to be most fundamental. Bulk cytoplasm of living eu-kariotic cells contains parallel-networks of individual microtubules which are interconnected by filamentous strands (so called MAPs or microtubule associated proteins). In this paper we report on the main physical features of microtubules focusing our attention on the microtubules dynamics, assembly (disassembly), nonlinear modes suitable for signaling and the spin-glass phase which is ideal for information processing.
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References
P. Dustin. 1984. Microtubules. Berlin:Springer
Dj. Koruga, Nanobiology 1, 5 (1992)
S. R. Hammeroff, Ultimate Computing. (Amsterdam:North-Holland, 1987)
S. Rasmussen, H. Karamporsala, R. Vavdyanatu, K. Jensen and S.R. Hammeroff. 1990. Physica D42: 428
S.R. Hammeroff and R.C. Watt., J. Theor. Biol. 98, 549 (1982)
H. Athenstaedt, Ann. N.Y. Acad. Sci. 238, 68 (1974)
L. Margulis, L. To and D. Chase, Science 200, 1118 (1978)
M. Barnett, in Proceedings of the Third Molecular Electronic Device Conference, edited by F. Carter. Washington, D.C.: Naval Reseach Laboratory (1987)
Y. Engleborghs, Nanobiology 1, 97 (1992)
T. Horio and H. Hotani, Nature 321, 605 (1986)
M.V. Sataric, J.A. Tuszyński and R.B. Žakula, Phys. Rev. E48, 589 (1993)
E.M. Madelkow and E. Mandelkow, Cell Motility and the Cytoskeleton 22, 235 (1992)
R. Melki, M.F. Carlier, D. Pantaloni and S.N. Timasheff, Biochem. 28, 9143 (1989)
M. Suzuki, Prog. Theor. Phys. 58, 1151 (1977)
K.H. Fischer, phys. stat. sol. (b) 116, 357 (1983)
K.H. Fischer, phys. stat. sol. (b) 130, 13 (1985)
H. Stebbings and C. Hunt, Cell Tiss. Res. 227, 609 (1982)
J.C. Kimball, Phys. Rev. B21, 2104 (1980).
S. Hameroff, S.A. Smith and R.C. Watt, Ann. N.Y. Acd. Sci. 466, 949 (1986)
J. Cronly-Dillon, D. Carden and C. Birks, J. Exp. Biol. 61, 443 (1974)
G. Bensimon and R. Chernat, Pharmacol. Biochem Behavior 38, 141 (1991)
F. Gutmann; in Modern Biochemistry, eds. F. Gutmann and H. Keyzer (Plenum Press, New York, 1986)
H. Haken, Synergetics: an Introduction (Berlin:Springer, 1990)
D.L. Stein (ed.), Spin Glasses and Biology (Singapore: World Scientific, 1992)
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Tuszyński, J.A., Trpisová, B., Sept, D., Satarić, M.V., Hameroff, S. (1995). The cell’s microtubules: self-organization and information processing properties. In: Peyrard, M. (eds) Nonlinear Excitations in Biomolecules. Centre de Physique des Houches, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08994-1_29
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DOI: https://doi.org/10.1007/978-3-662-08994-1_29
Publisher Name: Springer, Berlin, Heidelberg
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