Skip to main content
SpringerLink
Log in

Action of Histamine upon the Circulatory Apparatus

  • Chapter
Histamine and Anti-Histaminics

Abstract

The complexity of the effects of histamine upon the circulatory apparatus might explain what was called, in earlier times, the “histamine paradox”. When injected intravenously in cats and dogs, histamine produced a sharp fall in arterial blood pressure, though when perfused through isolated tissues or organs, not infrequently, a pure vaso-constrictor effect with decline in outflow was observed. This constrictor effect upon isolated perfused organs was particularly seen in cats (Dale and Richards, 1918). With improvement in the conditions of the perfusion experiments, and especially when dogs or monkeys were utilized as donors of the biological structure to be perfused, a vasodilation with increase in volume of the perfused limb and its venous outflow was observed (Burn and Dale, 1926). However, in rabbits and rats the main effect of histamine, when injected into the perfusing cannula, was a sharp decrease in outflow, in spite of the fact that when the amine was injected intravenously in the intact rat, a consistent fall in blood pressure could be observed. Even in the rabbit, under special conditions of anesthesia, histamine produced a fall of arterial blood pressure (Feldberg, 1927). Therefore, the paradox persists and can be understood only through an extensive analysis of the mode of action of histamine upon the cardio-vascular system.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abe, K.: Cit. in Feldberg and Schilf (1930). Tohoku J. exp. Med. 1, 389 (1920).

    Google Scholar 

  • Abramson, H. A., and M. Engel: Skin reactions; effect of allergic and histamine wheals on rate of absorption of dyes and blood from human cutis. J. invest. Derm. 1, 65 (1938).

    Article  CAS  Google Scholar 

  • Abramson, H. A., and H. Gettner: Skin reactions; lymphatic escape following electrophoresis of histamine and epinephrine. J. invest. Derm. 4, 243 (1941).

    Article  CAS  Google Scholar 

  • Ackermann, D., u. F. Kutscher: Untersuchungen über die physiologische Wirkung einer Secalebase und des Imidazoläthylamins. Z. Biol. 54, 387 (1910).

    CAS  Google Scholar 

  • Airila, Y.: Über die Ursache der tödlichen Blutdrucksenkung im akuten anaphylaktischen Schock beim Kaninchen. Skand. Arch. Physiol. 31, 388 (1914).

    Article  CAS  Google Scholar 

  • Alksne, I. F.: The passage of colloidal particles across the dermal capillary wall under the influence of histamine. Quart. J. exp. Physiol. 44, M (1959).

    Google Scholar 

  • Andrus, E. C., and H. B. Wilcox: Effects of anaphylaxis upon coronary arteries in the isolated heart. J. exp. Med. 69, 545 (1939).

    CAS  Google Scholar 

  • Anrep, G. V.: Lane Medical Lectures: Studies in cardiovascular regulation. Stanford Univ. Press, vol. 3 (1936).

    Google Scholar 

  • Anrep, G. V., and G. S. Barsoum: Appearance of histamine in the venous blood during muscular contraction. J. Physiol. (Lond.) 85, 409 (1935).

    CAS  Google Scholar 

  • Anrep, G. V., S. Salama and Z. Souidan: Liberation of histamine during reactive hyperaemia and muscle contraction in man. J. Physiol. (Lond.) 103, 297 (1944).

    CAS  Google Scholar 

  • Anrep, G. V., S. Salama and M. Talaat: Liberation of histamine by the heart muscle. J. Physiol. (Lond.) 86, 431 (1936).

    CAS  Google Scholar 

  • Arey, L. B.: Throttling veins in the livers of certain mammals. Anat. Rec. 81, 21 (1941).

    Article  Google Scholar 

  • Arey, L. B., and J. P. Simonds: The relation of the smooth muscle in the hepatic veins to shock phenomena. Anat. Rec. 18, 219 (1920).

    Article  Google Scholar 

  • Arnold, J.: Über das Verhalten der W andungen der Blutgefäße bei der Emigration weißer Blutkörper. Virchows Arch. path. Anat. 62, 487 (1875).

    Google Scholar 

  • Arnold, J.: Über die Kittsubstanz der Endothelien. Virchows Arch. path. Anat. 66, 77 (1876).

    Google Scholar 

  • Asciiheim, E., and B. W. Zweifach: Kinetics of blood protein leakage in inflammation. Circulat. Res. 9, 349 (1961).

    Article  Google Scholar 

  • Auer, J., and P. A. Lewis: The physiology of the immediate reaction of anaphylaxis in the guinea-pig. J. exp. Med. 12, 151 (1910).

    Article  PubMed  CAS  Google Scholar 

  • Baer, R., u. R. Rössler: Über die Bedeutung der Leber für die Blutverteilung; Durch- strömungsversuche an überlebender Hundeleber. Wien. klin. Wschr. 39, 1033 (1926).

    Google Scholar 

  • Baer, R., u. R. Rössler: Beiträge zur Pharmakologie der Lebergefäße. Über die Abhängigkeit der Histaminwirkung von der Durchströmungsrichtung (Versuche an isoliert durchströmter Hundeleber). Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 119, 204 (1927).

    Google Scholar 

  • Barbour, H.G.: Note on the action of histamine upon surviving arteries. J. Pharmacol. exp. Ther. 4 245 (1912–1913).

    Google Scholar 

  • Barcroft, J., and W. Feldberg: Cit. in Feldberg und Schilf (1930).

    Google Scholar 

  • Barsoum, G. S., and J. H. Gaddum: The liberation of histamine during reactive hyperaemia. J. Physiol. (Lond.) 85, 13P (1935).

    Google Scholar 

  • Barsoum, G. S., and F. H. Smirk: Observations on histamine yielding substance in plasma and red cells of normal human subjects and of patients with congestive heart failure. Clin. Sci. 2, 353 (1936).

    Google Scholar 

  • Bauer, W., H. H. Dale, L. T. Poulsson and D. W. Richards: The control of circulation through the liver. J. Physiol. (Lond.) 74, 343 (1932).

    CAS  Google Scholar 

  • Bauer, W., and D.W. Richards JR.: A vaso-dilator action of acetates. J. Physiol. (Lond.) 66, 371 (1928).

    Google Scholar 

  • Bayliss, W. M.: On the origin from the spinal cord of the vasodilator fibers of the hind limb and on the nature of these fibers. J. Physiol. (Lond.) 26, 173 (1901).

    CAS  Google Scholar 

  • Bauer, W., and Richards JR.: Further researches on antidromic nerve impulses. J. Physiol. (Lond.) 28, 276 (1902).

    Google Scholar 

  • Bennett, H. S.: The concepts of membrane flow and membrane vesiculation as mechanisms for active transport and ion pumping. J. biophys. biochem. Cytol. 2, suppl. 99 (1956).

    Google Scholar 

  • Bauer, W., J. H. Luft and J. C. Hampton: Morphological classification of vertebrate blood capillaries. Amer. J. Physiol. 196, 381 (1959).

    Google Scholar 

  • Benson, A. J., and B. T. Horton: Effects on continuous intravenous administration of histamine on the blood pressure and pulse rate in cases of multiple sclerosis. Proc. Mayo Clin. 20, 113 (1945).

    Google Scholar 

  • Berry, M. R., E. J. Baldes, H. E. Essex and K. G. Wakim Compensating plethismokymograph for measuring blood flow in human extremities. J. Lab. clin. Med. 33, 101 (1948).

    PubMed  CAS  Google Scholar 

  • Best, C. H., and E. W. Mchenry: Histamine. Physiol. Rev. 11, 371 (1931).

    CAS  Google Scholar 

  • Bhoola, K. D., J. D. Calle and M. Schachter: The effect of bradykinin, serum kallikrein and other endogenous substances on capillary permeability. J. Physiol. (Lond.) 152, 75 (1960).

    CAS  Google Scholar 

  • Bier, O. G., u. M. Rocha E Silva: Untersuchungen über Entzündungen. I. und Iii. Virchows Arch. path. Anat. 303, 325 u. 343 (1939).

    Google Scholar 

  • Billings, F. T., and B. G. Maegraith: Chemical changes in tissues following obstruction of blood supply. Quart. J. exp. Physiol. 27, 249 (1938).

    CAS  Google Scholar 

  • Blozzl, G., G. MenÉ et Z. Ovary: L’histamine et la granulopexie de l’endothélium vasculaire. Rev. Immunol. (Paris) 12, 320 (1948).

    Google Scholar 

  • Blozzl, G., G. MenÉ et Z. Ovary: Ricerche sui rapporti tra istamina e granuloplessia dell’endotelio vascolare. I. e II. Sperimentale 99, 341, 352 (1949).

    Google Scholar 

  • Blalock, A., and S. E. Levy: Partition of venous return during shock and after histamine. Amer. J. Physiol. 118, 734 (1937).

    CAS  Google Scholar 

  • Burch, G. E., and N. P. DE Pasquale: Bradykinin, digital flow, and the arteriovenous anastomoses. Circulat. Res. 10, 105 (1962).

    Article  PubMed  CAS  Google Scholar 

  • Burn, J. H.: The Background of Therapeutics. London, New York, Toronto: Oxford Univ. Press 1948.

    Google Scholar 

  • Burn, J. H., and H. H. Dale: The vaso-dilator action of histamine and its physiological significance. J. Physiol. (Lond.) 61, 185 (1926).

    CAS  Google Scholar 

  • Butler, V., J. W. Beard and A. Blalock: Experimental Shock. XI. A study of the alterations in the volume of blood and in the water content of blood and of muscle that are produced by histamine. Arch. Surg. 23, 848 (1931).

    Article  Google Scholar 

  • Carlsten, A., and D. R. Wood: Increased lymph histaminase in adrenalectomized cats and its restoration by adrenocortical extract but not by adrenaline. J. Physiol. (Lond.) 112, 142 (1951).

    CAS  Google Scholar 

  • Carrier, E. B.: Studies on the physiology of capillaries. V. The reaction of the human skin capillaries to drugs and other stimuli. Amer. J. Physiol. 61, 528 (1922).

    CAS  Google Scholar 

  • Chambers, R., and B. W. Zweifach: Capillary endothelial cement in relation to permeability. J. cell. comp. Physiol. 15, 255 (1940).

    Article  CAS  Google Scholar 

  • Chambers, R., and B. W. Zweifach: Intercellular cement and capillary permeability. Physiol. Rev. 27, 436 (1947).

    PubMed  CAS  Google Scholar 

  • Chappell, J. W., R. H. Ebert and W. R. Barclay: Effects of cortisone (adrenocortical preparation) on cutaneous histamine response of rabbits using Evans blue dye as indicator. J. Lab. clin. Med. 39, 896 (1952).

    PubMed  CAS  Google Scholar 

  • Cloetta, M., u. A. Anderes: Besitzen die Lungen Vasomotoren? Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 76, 124 (1914).

    Google Scholar 

  • Cobbin, L. B., and R. H. Thorp: The cardioactive principle in spleen. Brit. J. Pharmacol. 14, 392 (1959).

    PubMed  CAS  Google Scholar 

  • Coca, A. F.: The mechanism of the anaphylaxis reaction in the rabbit. J. Immunol. 4, 219 (1919).

    CAS  Google Scholar 

  • Code, C. F., C. Lowatt-Evans and R. A. Gregory: Blood histamine and cardiac activity. J. Physiol. (Lond.) 92, 344 (1938).

    CAS  Google Scholar 

  • Code, C. F., D. T. Cody, M. Hurn, J. C. Kennedy and M. J. Strickland: The simultaneous release of histamine and a histamine destroying factor during anaphylaxis in rats. J. Physiol. (Lond.) 156, 207 (1961).

    CAS  Google Scholar 

  • Copley, A. L., and V. Tsuluca: The antibradykinin action of fibrinolysin, etc. In: Symposium on Bradykinin, 1st International Pharmacological Meeting, Stockholm (1961). Biochem. Pharmacol. 10, 67 (1962).

    Google Scholar 

  • Crivellari, C. A.: Sensitiveness of adrenalectomized rats to certain toxin substances. Amer. J. Physiol. 81, 414 (1927).

    Google Scholar 

  • Cruickshank, E. W. H., and A. Subbarau: Reactions of isolated systemic and coronary arteries. J. Physiol. (Lond.) 64, 65 (1927).

    CAS  Google Scholar 

  • Cullumbine, H.: Leukotaxine and histamine. Nature (Lond.) 159, 841 (1947).

    Article  CAS  Google Scholar 

  • Cullumbine, H.:, and H. N. Rydon: A study of the formation, properties and partial purification of leukotaxine. Brit. J. exp. Path. 27, 33 (1946).

    PubMed  CAS  Google Scholar 

  • Dale, H. H.: The Herter Lectures. I. Capillary poisons and shock. II. Anaphylaxis. Iii. Chemical structure and physiological action. Bull. Johns Hopk. Hosp. 31, 257, 310, 373 (1920a).

    Google Scholar 

  • Dale, H. H.: Conditions which are conducive to the production of shock by histamine. Brit. J. exp. Path. 1, 103 (1920b).

    CAS  Google Scholar 

  • Dale, H. H.: The activity of the capillary blood vessels, and its relationship to certain forms of toxaemia. Brit. med. J. 1, 959, 1006 (1923).

    Article  PubMed  CAS  Google Scholar 

  • Dale, H. H.: Adventures in Physiology with Excursions into Autopharmacology. London: Pergamon Press 1953.

    Google Scholar 

  • Dale, H. H., and J. H. Gaddum: Reactions of denervated voluntary muscle and their bearing on the mode of action of parasympathetic and related nerves. J. Physiol. (Lond.) 70, 109 (1931).

    Google Scholar 

  • Dale, H. H., and P. P. Laidlaw: The physiological action of ß-iminazolylethylamine. J. Physiol. (Lond.) 41, 318 (1910).

    CAS  Google Scholar 

  • Dale, H. H., and P. P. Laidlaw: Histamine shock. J. Physiol. (Lond.) 52, 355 (1919).

    CAS  Google Scholar 

  • Dale, H. H., and P. P. Laidlaw: and A. N. Richards: The action of histamine: its bearing on traumatic toxaemia as a factor in shock. In: Spec. Rep. Ser. med. Res. Coun. (Lond.) 26, 8 (1919).

    Google Scholar 

  • Dale, H. H., and A. N. Richards: The vasodilator action of histamine and of some other substances. J. Physiol. (Lond.) 52, 110 (1918).

    CAS  Google Scholar 

  • Dale, H. H., and A. N. Richards: The depressor (vaso-dilator) action of adrenaline. J. Physiol. (Lond.) 62, 397 (1927).

    Google Scholar 

  • Dekanski, J.: The effect of protein hydrolysates (leukotaxine) on skin-histamine in cats. J. Physiol. (Lond.) 108, 233 (1949).

    CAS  Google Scholar 

  • Delaunojs, A. L.: Continuous measurement of blood flow and cardiac output by means of a cournand catheter equipped with thermistors. Arch. int. Pharmacodyn. 134, 245 (1961).

    Google Scholar 

  • Delaunojs, A. L.: R. Kordecki, H. Polet and J. R.Zewski: Cardiac output arterial blood pressure and pulmonary arterial pressure in histamine shock. Arch. int. Pharmacodyn. 120, 114 (1959).

    Google Scholar 

  • Dews, P. B., and J. D. P. Graham: The antihistamine substance 2786 R. P. Brit. J. Pharmacol. 1, 278 (1946).

    CAS  Google Scholar 

  • Deyrup, I. J.: Circulatory changes following the subcutaneous injection of histamine in dogs. Amer. J. Physiol. 142, 158 (1944).

    CAS  Google Scholar 

  • Deyrup, I. J., and W. S. Root: The effect of subcutaneous histamine injection on the cardiac output of the unanesthetized dog. Amer. J. Physiol. 148, 134 (1947).

    PubMed  CAS  Google Scholar 

  • Dixon, W. E., and J. C. Hoyle: Studies in pulmonary circulation; action of histamine J Physiol. (Loud.) 70, 1 (1930).

    CAS  Google Scholar 

  • Domenech-Alsina, F.: Studies on histamine hypotension. J. Physiol. (Lond.) 78, 54 (1933).

    Google Scholar 

  • Donnet, V., M. LéAndri et P. Zwirn: Effets de l’histamine sur la pression artérielle pulmonaire. C. R. Soc. Biol. (Paris) 140, 619 (1946).

    Google Scholar 

  • Drinker, C. K., and J. Bronfenbrenner: The pulmonary circulation in anaphylactic shock. J. Immunol. 9, 387 (1924).

    CAS  Google Scholar 

  • Duff, F., and R. F. Whelan: Effects of antihistamine substances on the response to histamine of the human forearm. Brit. J. Pharmacol. 9, 413 (1954).

    PubMed  CAS  Google Scholar 

  • Dumke, P. R., and C. F. Schmidt: Quantitative measurements of cerebral blood flow in macaque monkey. Amer. J. Physiol. 138, 421 (1943).

    Google Scholar 

  • Dunér, H., and B. Pernow: Cutaneous reactions produced by local administration of acetylcholine, acetyl-ß-methylcholine (methacholine), piperidine and histamine. Acta Physiol. scand. 25, 38 (1952).

    Article  PubMed  Google Scholar 

  • Dunér, H., and B. Pernow: Histamine and leukocytes in blood during muscular work in man. Scand. J. clin. Lab. Invest. 10, 394 (1958).

    Article  PubMed  Google Scholar 

  • Dunér, H., and B. Pernow: Histamine in man under physiological and pathological conditions. Acta med. scand. 168, 307 (1960).

    Article  PubMed  Google Scholar 

  • Dzsinicii, A., u. T. Gallé: Zum Wirkungsmechanismus des Histamins. Z. klin Med. 135, 669 (1939).

    Google Scholar 

  • Ebbecke, V.: Die lokale vasomotorische Reaktion (L. V. R.) der Haut und der inneren Organe. Pflügers Arch. ges. Physiol. 169, 1 (1917).

    Article  Google Scholar 

  • Ebbecke, V.: Capillarerweiterung, Urticaria und Schock. Klin Wschr. 2, 1725 (1923).

    Article  Google Scholar 

  • Eckenhoff, J. E., J. H. Hafkenschiel and C. M. Landmesser: The coronary circulation in the dog. Amer. J. Physiol. 148, 582 (1947).

    PubMed  CAS  Google Scholar 

  • Eichler, O.: Zur Pharmakologie der Hofmeisterschen Reihe. Habilitationsvortrag (1930).

    Google Scholar 

  • Eichler, O., u. H. Killian: Versuche zur Histaminwirkung am Kaninchen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 159, 606 (1931).

    Article  Google Scholar 

  • Einis, W.: Über die Wirkung des Pituitrins und ß-Imidazoläthylamins (Histamins) auf die Herzaktion. Versuche am isolierten Frosch-und Säugetierherzen. Biochem. Z. 52, 96 (1913).

    CAS  Google Scholar 

  • Elder, J. M., and A. A. Miles: The action of lethal toxins of gas-gangrene clostridia on capillary permeability. J. Pathol. Bact. 74, 133 (1957).

    Article  CAS  Google Scholar 

  • Elias, H., and H. Bengelsdorf: The structure of the liver of vertebrates. Acta anat. (Basel) 14, 297 (1952).

    Article  CAS  Google Scholar 

  • Elliott, D. F., E. W. Horton and G. P. Lewis: Actions of pure bradykinin. J. Physiol. (Loud.) 153, 473 (1960).

    CAS  Google Scholar 

  • Emmelin, K., and N. Emmelin: Histamine and reactive hyperaemia. Acta physiol. scand. 14, 16 (1947).

    Article  PubMed  CAS  Google Scholar 

  • Emmelin, N., G. Kahlson and F. Wicksell: Blood histamine in reactive hyperaemia and in muscle tetanus. Acta physiol. scand. 2, 110 (1941 a).

    Article  CAS  Google Scholar 

  • Emmelin, N., G. Kahlson and F. Wicksell: Histamine in plasma and methods of its estimation. Acta physiol. scand. 2, 123 (1941 b).

    Article  CAS  Google Scholar 

  • Effinger, H.: Über eine eigentümliche Hautreaktion hervorgerufen durch Ergamin. Wien. med. Wschr. 63, 1414 (1913).

    Google Scholar 

  • Effinger, H., u. A. Schürmeyer: Über den Kollaps und analoge Zustände. Klin. Wschr. 7, 777 (1928).

    Article  Google Scholar 

  • Essex, H. E., R. G. E. Wegria, J. F. Herrick and F. C. Mann: The effects of certain drugs on the coronary blood flow of the trained dog. Amer. Heart J. 19, 554 (1940).

    Article  CAS  Google Scholar 

  • Ettinger, G. H., G E Hall and J. Lang: The effect of repeated injections of histamine in the dog; on the heart and blood vessels. Canad. med. Ass. J. 35, 184 (1936).

    CAS  Google Scholar 

  • Euler, U. S. v., and A. Aström: Liberation of histamine and sympathin by stimulation of isolated splenic nerves from cattle. Acta physiol. scand. 16, 97 (1948).

    Article  Google Scholar 

  • Euler, U. S. v., u. G. Liljestrand: Die Wirkung von Adrenalin, Sympathol, Tyramin, Ephetonin und Histamin auf Gaswechsel und Kreislauf beim Menschen. Skand. Arch. Physiol. 55, 1 (1929). See also J. Physiol. (Lond.) 65, 22P (1928).

    Google Scholar 

  • Feigen, G. A., E. M. Vaughan-Williams, J. K. Peterson and C. B. Nielsen: Histamine release and intracell potentials during anaphylaxis in the isolated heart. Circulat. Res. 8, 713 (1960).

    Article  PubMed  CAS  Google Scholar 

  • Feldberg, W.: The peripheral innervation of the vessels of the external ear of the rabbit. J. Physiol. (Lond.) 61, 518 (1926).

    CAS  Google Scholar 

  • Feldberg, W.: The action of histamine on the blood vessels of the rabbit. J. Physiol. (Lond.) 63, 211 (1927).

    CAS  Google Scholar 

  • Feldberg, W.: Das Verhalten des Pfortaderdruckes nach Injektion von Histamin und Pepton in den Kreislauf der Katze. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 140, 156 (1929).

    Google Scholar 

  • Feldberg, W.: The role of mediators in the inflammatory tissue response. Int. Arch. Allergy 8, 15 (1956).

    Article  PubMed  CAS  Google Scholar 

  • Feldberg, W.:, G. Katz u. E. Schilf: Cit. in Feldberg and Schilf (1930).

    Google Scholar 

  • Feldberg, W., and C. H. Kellaway: The circulatory and pulmonary effects of the venom of the Australian Copperhead (Denisonia superba). Aust. J. exp. Biol. med. Sci. 15, 81 (1937a).

    Article  CAS  Google Scholar 

  • Feldberg, W., and C. H. Kellaway: Circulatory effects of the venom of the Indian cobra (Naia naia) on dogs. Aust. J. exp. Biol. med. Sci. 15, 441 (1937b).

    Article  CAS  Google Scholar 

  • Feldberg, W., and A. A. Miles: Regional variations of increased permeability of skin capillaries by a histamine liberator and their relation to the histamine content of the skin. J. Physiol. (Lond.) 120, 205 (1953).

    CAS  Google Scholar 

  • Feldberg, W., u. E. Schilf: Histamin. Seine Pharmakologie und Bedeutung für die Humoralphysiologie. Berlin: Springer 1930.

    Google Scholar 

  • Feldberg, W., u. H. Zernik: Das Verhalten des Pfortaderdruckes nach Injektion von Histamin und Pepton in den Kreislauf des Hundes. Pflügers Arch. ges. Physiol. 220, 738 (1928).

    Article  CAS  Google Scholar 

  • Feldberg, W., and J. Talesnik: Reduction of tissue histamine by compound 48/80. J. Physiol. (Lond.) 120, 550 (1953).

    CAS  Google Scholar 

  • Felix, W.: Histaminwirkung auf Blutdruck und Durchblutung des Mesenteria und des Femoralisgebietes unter abnormen Kreislaufverhältnissen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 238, 101 (1960).

    CAS  Google Scholar 

  • Field, M. E., and C. K. Drinker: Action of histamine on bronchioles and pulmonary vessels of the guinea pig. Amer. J. Physiol. 93, 138 (1930).

    CAS  Google Scholar 

  • Flatow, E. M.: Die Wirkung des Histaminschocks auf das Blutbild. II. Tagung d. Deut. Physiol. Gesellschaft in Kiel. Ber. ges. Physiol. 50, 301 (1929).

    Google Scholar 

  • Flatow, E., u. H. Htttel: Cit. in Feldberg und Schilf (1930).

    Google Scholar 

  • Fleckenstein, A.: A quantitative study of antagonists of adrenaline on the vessels of the rabbit’s ear. Brit. J. Pharmacol. 7, 553 (1952).

    PubMed  CAS  Google Scholar 

  • Fleisch, A.: Die Wirkung von Histamin, Acetylcholin und Adrenalin auf die Venen. Pflügers Arch. ges. Physiol. 228, 351 (1931).

    CAS  Google Scholar 

  • Fleisch, A.,, u. I. Sibul: Über nutritive Kreislaufregulierung. II. Die Wirkung von pH, intermediären Stoffwechselprodukten und anderen biochemischen Verbindungen. Pflügers Arch. ges. Physiol. 231, 787 (1933).

    CAS  Google Scholar 

  • Fleisch, A., u. P. Weger: Über eine gefäßerweiternde Substanz der Erythrocyten. Pflügers Arch. ges. Physiol. 239, 476 (1937).

    CAS  Google Scholar 

  • Florey, H.: Anniversary address. Proc. roy. Soc. Med. 155, 314 (1961).

    Google Scholar 

  • Florey, H., J. C. F. Poole and G. A. Meek: Endothelial cells and “cement” lines. J. Pathol. Bact. 77, 625 (1959).

    Article  CAS  Google Scholar 

  • Folkow, B., K. Haeger and G. Kahlson: Observations on reactive hyperaemia as related to histamine, on drugs antagonizing vasodilatation induced by histamine and on vasodilator properties of adenosine triphosphate. Acta physiol. scand. 15, 264 (1948).

    Article  CAS  Google Scholar 

  • Fortier, C.: Facteurs humoraux et nerveux de la réponse hypophysosurrénalienne au stress. Acta neuroveg. (Wien) 5, 55 (1952).

    Article  CAS  Google Scholar 

  • Fox, R. H., R. Goldsmith, D. J. Kidd and G. P. Lewis: Bradykinin as a vaso-dilator in man. J. Physiol. (Lond.) 157, 589 (1961).

    CAS  Google Scholar 

  • Primmer, M.: Beeinflussung der Durchlässigkeit von Blut-Capillaren der Kaninchenhaut für Makromoleküle durch einige biogene, gefäßaktive Substanzen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 242, 390 (1961).

    Google Scholar 

  • FÜHner, H., and E. H. Starling: Experiments on the pulmonary circulation. J. Physiol. (Lond.) 46, 286 (1913).

    Google Scholar 

  • Gaddum, J. H.: Beiträge zum Histaminproblem. Acta neuroveg. (Wien) 4, 268 (1952).

    Article  CAS  Google Scholar 

  • Ganter, G., u. A. Schretzenmayr: Über die Wirkung des Histamins auf die Nierengefäße. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 147, 123 (1929).

    Google Scholar 

  • Ganter, G., u. A. Schretzenmayr: Über die Wirkung des Histamins auf den Kreislauf der Katze. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 147, 128 (1929).

    Google Scholar 

  • Ganter, G., u. A. Schretzenmayr: Über den Mechanismus der Histaminwirkung beim Hunde. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 151, 49 (1930).

    CAS  Google Scholar 

  • Goodall, M.: Studies of adrenaline and noradrenaline in mammalian heart and suprarenals. Acta physiol. scand. 24, Suppl. 85, 1 (1951).

    Google Scholar 

  • Gordon, M. L.: An immediate response of the demedullated adrenal gland to stress. Endocrinology 47, 13 (1950).

    Article  PubMed  CAS  Google Scholar 

  • Gray, F. D., and A. S. Field: Fluid interchange at the pulmonary capillary wall in lung edema. Yale J. Biol. Med. 34, 75 (1961).

    Google Scholar 

  • Guillemin, R.: A re-evaluation of acetylcholine, adrenaline, nor-adrenaline and histamine as possible mediators of the pituitary adrenocorticotrophic activation by stress. Endocrinology 56, 248 (1955).

    Article  PubMed  CAS  Google Scholar 

  • Guillemin, R., and C. Fortier: Role of histamine in the hypothalamohypophyseal response to stress. Trans. N. Y. Acad. Sci. 15, 138 (1953).

    PubMed  CAS  Google Scholar 

  • Gunn, J. A.: The action of histamine on the heart and coronary vessels. J. Pharmacol. exp. Ther. 29, 325 (1926).

    Google Scholar 

  • Haddy, F. J.: Effect of histamine upon large and small vessels of dog forelimb. Circulation 18, 732 (1958).

    Google Scholar 

  • Haddy, F. J.: Effect of histamine on small and large vessel pressure in the dog foreleg. Amer. J. Physiol. 198, 161 (1960).

    PubMed  CAS  Google Scholar 

  • Haley, T. J., and D. H. Harris: Effect of topically applied antihistaminic drugs on mammalian capillary bed. J. Pharmacol. exp. Ther. 95, 293 (1949).

    PubMed  CAS  Google Scholar 

  • Halpern, B. N.: Experimental research on new series of chemical substances with powerful antihistaminic activity; thiodiphenylamine derivatives. J. Allergy 18, 263 (1947).

    Article  PubMed  CAS  Google Scholar 

  • Halpern, B. N., B. Benacerraf and M. Griot: Potentiation by adrenaline (epinephrine) of protective effect of cortisone (adrenocortical preparation) on histamine toxicity in adrenalectomized mice. Proc. Soc. exp. Biol. (N. Y.) 79, 37 (1952).

    CAS  Google Scholar 

  • Halpern, B. N., B. Benacerraf and M. Griot: Roles of cortisone, desoxycorticosterone (adrenocortical preparation) and adrenaline (epinephrine) in protecting adrenalectomized animals against hemorrhagic, traumatic and histamine shock. Brit. J. Pharmacol. 7, 287 (1952).

    PubMed  CAS  Google Scholar 

  • Halpern, B. N., et J. Roux: Interférence entre l’immunisation par l’Hémophilus pertussis et l’intoxication histaminique. C. R. Soc. Biol. (Paris) 143, 923 (1949).

    Google Scholar 

  • Halpern, B. N., and D. R. Wood: The action of promethazine (phenergan) in protecting mice against death to histamine. Brit. J. Pharmacol. 5, 510 (1950).

    PubMed  CAS  Google Scholar 

  • Harmer, I. M., and K. E. Harris: Observations on the vascular reactions in man in response to histamine. Heart 13, 381 (1926).

    Google Scholar 

  • Hashimoto, H.: Transient change in the auriculoventricular condition following the injection of histamine. Arch. intern. Med. 35, 609 (1925).

    CAS  Google Scholar 

  • Hashimoto, H.: Blood chemistry in acute histamine intoxication. J. Pharmacol. exp. Ther. 25, 381 (1925–1926).

    Google Scholar 

  • Rechter, O.: Effect of histamine upon capillary permeability in the skin and muscle of normal and adrenalectomized rats. Endocrinology 32, 135 (1943).

    Article  Google Scholar 

  • Hemingway, A., and R. J. S. Mcdowall: On the survival of striped mammalian muscles. J. Physiol. (Lond.) 61, 6 (1926).

    Google Scholar 

  • Hemingway, A., and R. J. S. Mcdowall: The chemical regulation of capillary tone. J. Physiol. (Lond.) 62, 166 (1926).

    CAS  Google Scholar 

  • Herxheimer, A., and M. Schachter: Wheal and flare in human skin produced by histamine and other substances. Nature (Lond.) 183, 1501 (1959).

    Article  Google Scholar 

  • Hilton, S. M.: Experiments on the post-contraction hyperaemia of skeletal muscle. J. Physiol. (Lond.) 120, 230 (1953).

    CAS  Google Scholar 

  • Hilton, S. M.: A peripheral arterial conducting mechanism underlying dilatation of the femoral artery and concerned in functional vasodilatation in skeletal muscle. J. Physiol. (Loud.) 149, 93 (1959).

    CAS  Google Scholar 

  • Hilton, S. M.: Local mechanisms regulating peripheral blood flow. Physiol. Rev. 42, Suppl. 5, 265 (1962).

    CAS  Google Scholar 

  • Hilton, S. M., and G. P. Lewis: Functional vasodilatation in the submandibular salivary gland. Brit. med. Bull. 13 189 (1957)…

    Google Scholar 

  • Hochrein, M., u. R. Meier: Über den Mechanismus der Blutdrucksenkung durch Histamin. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 153, 309 (1930).

    CAS  Google Scholar 

  • Holton, F. A., and P. Holton: Vasodilator activity of spinal roots. J. Physiol. (Lond.) 118, 310 (1952).

    CAS  Google Scholar 

  • Holton, F. A., and P. Holton: The possibility that Atp is a transmitter at sensory nerve endings. J. Physiol. (Loud.) 119, 50 P (1953).

    Google Scholar 

  • Holton, P.: The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves. J. Physiol. (Lond.) 145, 494 (1959).

    CAS  Google Scholar 

  • Holton, P., and W. L. M. Perry: On the transmitter responsible for antidromic vaso-dilatation in the rabbit’s ear. J. Physiol. (Lond.) 114, 240 (1951).

    CAS  Google Scholar 

  • Holtz, P.: Über die Wirkung von Cholinestern und biogenen Aminen am isolierten Vorhof des Herzens. Acta neuroveg. (Wien) 21, 445 (1960).

    Article  CAS  Google Scholar 

  • Hooker, D. R.: The functional activity of the capillaries and venules. Amer. J. Physiol. 54, 30 (1920).

    Google Scholar 

  • Horton, B. T.: Head and face pain. Collected Papers Mayo Clin. Mayo Found. 36, 520 (1944).

    Google Scholar 

  • Horton, B. T.: Histaminic cephalalgia: differential diagnosis and treatment. Collected Papers Mayo Clin. Mayo Found. 47, 384 (1955).

    Google Scholar 

  • Horton, B. T., M. R. Grace and A. W. Adson: Observations on some differences in the vasomotor reactions of the hands and feet. Proc. Mayo Clin. 11, 433 (1936).

    Google Scholar 

  • Houssay, R. H.: Sensibilité vis-à-vis de l’histamine des rats à surrénales accessoires ou démédullisés. C. R. Soc. Biol. (Paris) 149, 1664 (1955).

    CAS  Google Scholar 

  • Hteper, W. C., and C. T. Iciiniowski: Hematic and organic reaction in standardized and graded histamine shock in dogs. J. Pharmacol. exp. Ther. 78, 127 (1943).

    Google Scholar 

  • Hunt, R.: (1917). Cit. in Feldberg und Schilf (1930).

    Google Scholar 

  • Ibrahim, F. D., G. Stella and M. Talaat: The mechanism of antidromic vasodilatation. Quart. J. exp. Physiol. 36, 189 (1951).

    CAS  Google Scholar 

  • Inchley, O.: The action of histamine on the veins. Brit. med. J. 1, 679 (1923).

    Article  PubMed  CAS  Google Scholar 

  • Inchley, O.: Histamine shock. J. Physiol. (Lond.) 61, 282 (1926).

    CAS  Google Scholar 

  • Ingle, D.: Resistance of the rat to histamine shock after destruction of the adrenal medulla. Amer. J. Physiol. 118, 57 (1937).

    CAS  Google Scholar 

  • Jancsô, N.: (1942). Cit. in Jancsó (1961).

    Google Scholar 

  • Jancsô, N.: Histamine as a physiological activator of the reticulo-endothelial system. Nature (Lond.) 160, 227 (1947).

    Article  Google Scholar 

  • Jancsô, N.: Inflammation and the inflammatory mechanisms. J. Pharm. Pharmacol. 13 577 (1961).

    Google Scholar 

  • Jancsô, N.:, u. A. Jancs>ó-Gabor: Wirkung von Anticoagulantien auf entziindliche Gewebsreaktionen. N.unyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 238, 83 (1960).

    Google Scholar 

  • Johnson, G. S., and A. Blalock: Experimental shock. Xii. Study of the effects of hemorrhage, of trauma to muscles, of trauma to intestine, of burns and of histamine on the cardiac output and on blood pressure of dogs. Arch. Surg. 23, 855 (1931).

    Article  Google Scholar 

  • Karady, S.: Histaminempfindlichkeit. Wien. klin. Wschr. 1, 622 (1934).

    Google Scholar 

  • Kellaway, C. H., and S. J. Cowell: On the concentration of the blood and the effects of histamine in adrenal insufficiency. J. Physiol. (Lond.) 57, 82 (1923).

    Google Scholar 

  • Keller, C. J.: Untersuchungen über die Gehirndurchblutung; gibt es eine Autonomie der Gehirngefäße. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 154, 357 (1930).

    CAS  Google Scholar 

  • Kewitz, H., u. K. Morgan: Über die Bedeutung des Histamins für die Phagocytose von Tuschepartikelchen durch Endothelien. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 223, 399 (1954).

    CAS  Google Scholar 

  • Kind, L. S.: The altered reactivity of mice after immunization with Hemophilus pertussis vaccine. J. Immunol. 70, 411 (1953).

    PubMed  CAS  Google Scholar 

  • Kind, L. S.: Inhibition of histamine death in pertussis-inoculated mice by cortisone and neoantergan. J. Allergy 24, 52 (1953).

    Article  PubMed  CAS  Google Scholar 

  • Kind, L. S.: Antagonism of cortisone to body temperature reducing effect of histamine. Proc. Soc. exp. biol. (N. Y.) 85, 371 (1954).

    CAS  Google Scholar 

  • Kind, L. S.: The altered reactivity of mice after inoculation with Bordetella pertussis vaccine. Bact. Rev. 22, 173 (1958).

    PubMed  CAS  Google Scholar 

  • Kind, L. S., and R. H. Gadsden: Adrenal function tests in mice sensitized to histamine with Hemophilus pertussis vaccine. Proc. Soc. exp. biol. (N. Y.) 84, 373 (1953).

    CAS  Google Scholar 

  • Kirch, E.: Über tierexperimentelle Erzeugung von tonogener Dilatation und Hypertrophie des rechten Herzens durch hochdosierte Histamininjektionen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 171, 691 (1933).

    CAS  Google Scholar 

  • Kisch, F.: Tierexperimentelle Untersuchungen über den Einfluß des Histamins auf die Zirkulationsgröße. Z. ges. exp. Med. 66, 799 (1929).

    Google Scholar 

  • Klisiecki, A., u. W. Holobut: Die linke Herzkammer als Herdsitz des Histaminschocks. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 186, 57 (1937).

    Article  Google Scholar 

  • Knisely, M. H.: A method of illuminating living structures for microscopic study. Anat. Rec. 64, 499 (1936).

    Article  Google Scholar 

  • Knisely, M. H.: An improved fused quartz living tissue illuminator. Anat. Rec. 71, 503 (1938).

    Article  CAS  Google Scholar 

  • Konzett, H., and E. Stürmer: Biological activity of synthetic polypeptides with bradykininlike properties. Brit. J. Pharmacol. 15, 544 (1960).

    PubMed  CAS  Google Scholar 

  • Koopmans, S.: Functions of blood vessels in brain; effect of some narcotics, hormones and drugs. Arch. néerl. Physiol. 24, 250 (1939).

    Google Scholar 

  • Kowalewski, K., and C. Wisniewski: Oxygen content and pH of arterial, venous and portal blood in dogs after histamine. Proc. Soc. exp. biol. (N. Y.) 109, 161 (1962).

    CAS  Google Scholar 

  • Krogh, A.: Anatomy and physiology of the capillaries. New Haven, Conn.: Yale Univ. Press 1929. Kusuetzowsky, N.: Über den Einfluß lokaler Reize auf den Prozeß der Vitalfärbung. Z. ges. exp. Med. 44, 646 (1924).

    Google Scholar 

  • Kwiatkowski, H.: Observations on the relation of histamine to reactive hyperaemia. J. Physiol. (Lond.) 100, 147 (1941).

    CAS  Google Scholar 

  • Kwiatkowski, H.: Histamine in nervous tissue. J. Physiol. (Lond.) 102, 32 (1943).

    CAS  Google Scholar 

  • Lamson, P. D., A. F. Abt, C. A. Oothuisen and S. M. Rosenthal: The influence of arterial blood supply to the liver on hemoglobin concentration in certain acute conditions. J. Pharmacol. exp. Ther. 21, 401 (1923).

    CAS  Google Scholar 

  • Lamson, R. W.: Skin reactions to pollen and to histamine. Proc. Soc. exp. biol. (N. Y.) 26, 611 (1929).

    Google Scholar 

  • Landis, E. M.: Micro-injection studies of capillary permeability. I. Factors in the production of capillary stasis. Amer. J. Physiol. 81, 124 (1927).

    CAS  Google Scholar 

  • Landis, E. M.: Micro-injection studies of capillary blood pressure in human skin. Heart 15, 209 (1930).

    Google Scholar 

  • Landis, E. M.: Micro-injection studies of capillary blood pressure in Raynaud’sdisease. Heart 15, 247 (1930).

    Google Scholar 

  • Landis, E. M.: Capillary pressure and capillary permeability. Physiol. Rev. 14, 404 (1934).

    Google Scholar 

  • Langley, J. N.: Antidromic action. I. J. Physiol. (Lond.) 57, 428 (1923).

    CAS  Google Scholar 

  • Landis, E. M.: Antidromic action. II. Stimulation of the peripheral nerves of the cat’s hind foot. J. Physiol. (Loud.) 58, 49 (1923).

    Google Scholar 

  • Lecomte, J.: Sur les facteurs surrénaliens qui conditionnent la résistance du rat intoxiqué par l’histamine. Arch. int. Physiol. Biochem. 69, 563 (1961).

    CAS  Google Scholar 

  • Lee, J. S.: Microscopic observations on the action of histamine on small blood vessels. Amer. J. Physiol. 190, 503 (1957).

    PubMed  CAS  Google Scholar 

  • Lewis, G. P.: Pharmacological actions and functions of bradykinin. In: Symposium on Bradykinin 1st International Pharmacological Meeting (1961). Biochem. Pharmacol. 10, 29 (1962).

    Google Scholar 

  • Lewis, P. A.: The distribution of trypan red to the tissues and vessels of the eye as influenced by congestion and early infection. J. exp. Med. 23, 669 (1916).

    Article  PubMed  CAS  Google Scholar 

  • Lewis, T.: The blood vessels of the human skin and their responses. London: Shaw amps Sons, Ltd., 1927.

    Google Scholar 

  • Lewis, T., and R. T. Grant: Vascular reactions of the skin to injury. II. The liberation of a histamine-like substance in injured skin: the underlying cause of factitious urticaria and of wheals produced by burning, and observations upon the nervous control of certain skin reactions. Heart 11, 209 (1924).

    CAS  Google Scholar 

  • Lewis, T., and H. M. Marvin: Herpes Zoster and antidromic impulses. J. Physiol. (Lond.) 62 19 (1926–1927).

    Google Scholar 

  • Lewis, T., and H. M. Marvin: Observations relating to vasodilatation arising from antidromic impulses, to herpes zoster and trophic effects. Heart 14, 27 (1927).

    Google Scholar 

  • Luisada, A.: Neuere Untersuchungen über die Wirkung des Morphins auf Blutgefäße. Besonders der Lungengefäße. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 132, 296 (1928).

    CAS  Google Scholar 

  • Maccardy, J. I., und H. M. Evans: Experimentelle Läsionen des Centralnervensystems, untersucht mit Hilfe der vitalen Färbung. Berl. klin. Wschr. 49, 1695 (1912).

    Google Scholar 

  • Mccarrel, J. D., and C. K. Drinker: Cervical lymph production during histamine shock in the dog. Amer. J. Physiol. 133, 64 (1941).

    Google Scholar 

  • Mcclellan, R. H.,and E. W. Goodpasture: A method of demonstrating experimental cross lesions of the central nervous system. J. med. Res. 44 20 (1923–1924).

    Google Scholar 

  • Mcdowall, R. J. S.: On the nature of histamine action. J. Physiol. (Lond.) 57, 146 (1923).

    CAS  Google Scholar 

  • Majno, G., and G. E. Palade: Studies on inflammation. I. Effect of histamine and serotonin on vascular permeability. An electron microscopic study. J. biophys. biochem. Cytol. 11, 571 (1961).

    Article  CAS  Google Scholar 

  • Majno, G., and G. E. Palade, and G. I. Sciioefl: Studies on inflammation. II. The site of action of histamine and serotonin along the vascular tree. A topographic study. J. biophys. biochem. Cytol. 11, 607 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Malkiel, S.: Anaphylactic shock in mouse vaccinated with Hemophilus pertussis; studies on adrenal gland. J. Allergy 27, 445 (1956).

    Article  PubMed  CAS  Google Scholar 

  • Malkiel, S., and B. J. Hargis: Anaphylactic shock in the Pertussis-vaccinated mouse. J. Allergy 23, 352 (1952a).

    Article  PubMed  CAS  Google Scholar 

  • Malkiel, S., and B. J. Hargis: Anaphylactic shock in the Pertussis-vaccinated mouse. Proc. Soc. exp. Biol. (N. Y.) 80, 122 (1952 b).

    Google Scholar 

  • Malkiel, S., and B. J. Hargis: Histamine sensitivity and anaphylaxis in the Pertussis-vaccinated rat. Proc. Soc. exp. Biol. (N. Y.) 81 689 (1952 c).

    CAS  Google Scholar 

  • Malkiel, S., and B. J. Hargis, and S. M. Feinberg: Anaphylactic shock in the mouse vaccinated with Hemophilus Pertussis. Iii. Antigens, antibody, and passive transfer studies. J. Immunol. 71, 3H (1953).

    Google Scholar 

  • Mannaioni, P. F.: Interaction between histamine and dichloroisoproterenol, hexamethonium, pempidine and diphenhydramine in normal and reserpine treated heart preparations. Brit. J. Pharmacol. 15, 500 (1960).

    PubMed  CAS  Google Scholar 

  • Manwaring, W. H., R. E. Monaco, and H. D. Marino: Hepatic reactions in anaphylaxis. VI. Histamine reactions in isolated canine tissues. J. Immunol. 8, 217 (1923).

    CAS  Google Scholar 

  • Marimoto, M.: Über die Wirkung von Histamin auf die Nierengefäße. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 135, 194 (1928).

    Google Scholar 

  • Marmorston-Gottesman, J., and J. Gottesman: The use of histamine as a standard test for diminished resistance in suprarenalectomized rats. J. exp. Med. 47, 503 (1928).

    Article  PubMed  CAS  Google Scholar 

  • Marmorston-Gottesman, J., and D. Perlas: Effect of injections of cortin on resistance of suprarenalectomized rats to large amounts of histamine. Proc. Soc. exp. Biol. (N. Y.) 28, 1022 (1931).

    Google Scholar 

  • Marshall, P B: The influence of adrenal cortical deficiency on the histamine content of rat tissues. J. Physiol. (Lond.) 102, 180 (1943).

    CAS  Google Scholar 

  • Mateeff, D., u. M. Schneider: Analyse der peripheren Kreislaufswirkungen des Histamins. Pflügers Arch. ges. Physiol. 236, 606 (1935).

    Article  Google Scholar 

  • Matoltsy, A. G., and M. Matoltsy: The action of histamine and antihistaminic substance on the endothelial cells of the small capillaries of the skin. J. Pharmacol. exp. Ther. 102, 237 (1951).

    PubMed  CAS  Google Scholar 

  • Matsimoto, Y.: Cit. in Feldberg und Schilf (1930).

    Google Scholar 

  • Mautner, H.: The role of veins in the circulation. Arch. Pediatr. 72, 387 (1955).

    PubMed  CAS  Google Scholar 

  • Mautner, H., u. E. P. Pick: Über die durch „Schockgifte“ erzeugten Zirkulationsstörungen. Munch. med. Wschr. 62, 1141 (1915).

    CAS  Google Scholar 

  • Mautner, H., u. E. P. Pick: Über die durch „Schockgifte“ erzeugten Zirkulationsstörungen. II. Das Verhalten der überlebenden Leber. Biochem. Z. 127, 72 (1922).

    CAS  Google Scholar 

  • Mautner, H., u. E. P. Pick: Über die durch „Schockgifte“ erzeugten Zirkulationsstörungen. Iii. Der Einfluß der Leber auf Blutdruck und Schlagvolumen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 142, 271 (1929).

    Article  CAS  Google Scholar 

  • Mayer, R. L.: The activity of pyribenzamine and related compounds with special reference to their mode of action. Ann. N. Y. Acad. Sci. 50, 1127 (1950).

    Article  PubMed  CAS  Google Scholar 

  • Mayer, R. L., and D. Brousseau: Anti-histaminic substances in histamine poisoning and anaphylaxis in mice. Proc. Soc. exp. Biol. (N. Y.) 63, 187 (1946).

    Article  CAS  Google Scholar 

  • Menkin, V.: Studies on Inflammation. Xiv. Isolation of the factor concerned with increased capillary permeability in injury. J. exp. Med. 67, 129 (1938).

    Article  PubMed  CAS  Google Scholar 

  • Menkin, V.: Studies on Inflammation. Xvi. On the formation of a chemotactic substance by enzymatic action. J. exp. Med. 67, 153 (1938).

    Article  PubMed  CAS  Google Scholar 

  • Menkin, V.: A note on the differences between histamine and leukotaxine. Proc. Soc. exp. Biol. (N. Y.) 40, 103 (1939).

    CAS  Google Scholar 

  • Menkin, V.: Dynamics of Inflammation. New York: McMillan Co. 1940.

    Google Scholar 

  • Miles, A A, and E. M. Miles: Vascular reaction to histamine, histamine liberator (compound 48/80, phenylethylamine compounds) and leukotaxine in skin of guinea pigs. J. Physiol. (Lond.) 118, 228 (1952).

    CAS  Google Scholar 

  • Miles, A A, and D. L. Wilhelm: Enzyme-like globulins from serum reproducing the vascular phenomena of inflammation. An activable permeability factor and its inhibitor in guinea pig serum. J. exp. Pathol. 36, 71 (1955).

    CAS  Google Scholar 

  • Miles, A A, and D. L. Wilhelm: The activation of endogenous substances inducing pathological increases of capillary permeability. 51. Biochem. Response to Injury, Symposium, Semmering, Austria, 1958 (Publ. 1960 ).

    Google Scholar 

  • Möller, H., and H. Rorsman: Studies on vascular permeability factors with sodium fluorescein. I. The effect of intracutaneously injected histamine, human serum and its protein fractions in normal individuals. Acta derm.-venereol. (Stockh.) 38, 233 (1958).

    Google Scholar 

  • Möller, H., and H. Rorsman: Studies on vascular permeability factors with sodium fluorescein. Iii. The effect in man of intracutaneously injected 5-hydroxytryptamine. Acta derm-venereol. (Stockh.) 39, 12 (1959).

    Google Scholar 

  • Moon, V. H.: Shock and Related Capillary Phenomena. Oxford, Med. Publications, New York 1938.

    Google Scholar 

  • Moon, V. H.: Circulatory failure of capillary origin. J. Amer. med. Ass. 114, 1312 (1940).

    Article  Google Scholar 

  • Moon, V. H., M M Lieber, and P. J. Kennedy: Histamine and leukocytosis. Arch. Path. 20, 1209 (1935).

    Google Scholar 

  • Moran, N. C., and M. E. Perkins: Adrenergic blockade of the mammalian heart by a dichloro-analogue of isoproterenol. J. Pharmacol. exp. Ther. 124, 223 (1958).

    PubMed  CAS  Google Scholar 

  • Morel, F. E., et M. Mardis: Actions de l’histamine sur le système vasculaire du lapin étudiées au moyen du radiosodium. C. R. Soc. Biol. (Paris) 143, 464 (1949).

    CAS  Google Scholar 

  • Mota, I.: Mast cell and histamine in rat anaphylaxis. The effect of Hemophilus pertussis. Nature (Loud.) 182, 1021 (1958).

    Article  CAS  Google Scholar 

  • Muller, E. A., H. Salomon u. G. Zielzer: Die Wirkung von Histamin auf Herz und Lungen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 164, 441 (1932).

    CAS  Google Scholar 

  • Munoz, J., and L. F. Schuchardt: Studies on the sensitivity of mice to histamine following injections of Hemophilus pertussis. J. Allergy 24, 330 (1953).

    Article  PubMed  CAS  Google Scholar 

  • Munoz, J., and L. F. Schuchardt: Sensitivity to histamine of adrenalectomized mice from different strains. J. Allergy 25, 125 (1954).

    Article  PubMed  CAS  Google Scholar 

  • Munoz, J., and L. F. Schuchardt:, and W. F. Verwey: Anaphylaxis in Hemophilus pertussis, treated mice. I. Passive anaphylaxis with heterologous rabbit antibody. J. Immunol. S0, 77 (1958).

    Google Scholar 

  • Naranjo, P., and E. B. Naranjo: Pressor effect of histamine in the rabbit. J. Pharmacol. exp. Ther. 123, 16 (1958).

    PubMed  CAS  Google Scholar 

  • Narayana, B.: Vaso-constricteurs et vaso-dilateurs coronaires. C. R. Soc. Biol. (Paris) 114, 550 (1933).

    Google Scholar 

  • Neuwelt, F., S. O. Levinson and H. Necheles: Studies on shock. Iii. Variability of the shock syndrome in toxic drug shock. Surgery 9, 503 (1941).

    CAS  Google Scholar 

  • Noble, R., and J. Collip: The response of normal, hypophysectomized and adrenalectomized rats to histamine administration. Amer. J. Physiol. 133, 623 (1941).

    CAS  Google Scholar 

  • Okuneff, N.: Über den Einfluß lokaler thermischer Reize auf die Abwanderung eines intravenous injizierten kolloidalen Farbstoffs aus dem Blut. Virchows Arch. path. Anat. 204, 261 (1924).

    CAS  Google Scholar 

  • Osawa, Y.: Die Durchblutung der Katzenlunge nach Histamin. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 156, 309 (1930).

    CAS  Google Scholar 

  • Osawa, Y.: Die Bedeutung der lungengefäßverengernden Wirkung des Histamins für Blutdruck und Venendruck der Katze. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 156, 323 (1930).

    CAS  Google Scholar 

  • Palane, G. E.: Fine structure of blood capillaries. J. appl. Physiol. 24, 1429 (1953).

    Google Scholar 

  • Palane, G. E.: Transport in quanta across the blood capillaries. Anat. Rec. 136, 254 (1960).

    Google Scholar 

  • Palane, G. E.: Blood capillaries of the heart and other organs. Circulation 24, 368 (1961).

    Article  Google Scholar 

  • Pappenreimer, J. R.: Capillary permeability deductions concerning the number and dimensions of ultramicroscopic openings in the capillary wall. Ann. N. Y. Acad. Sci. 55, 465 (1952).

    Article  Google Scholar 

  • Parfentjev, I. A.: Anaphylaxis and histamine shock in mice. Proc. Soc. exp. Biol. (N. Y.) 89, 297 (1955).

    CAS  Google Scholar 

  • Parfentjev, I. A., and M. A. >Goodlrre: Histamine shock in mice sensitized with Hemophilus pertussis vaccine. J. Pharmacol. exp. Ther. 92, 411 (1948).

    PubMed  CAS  Google Scholar 

  • Parrot,J. L.: The place of histamine in neurohumoral transmission.Pharmacol. Rev.6,119(1954).

    Google Scholar 

  • Parrot,J. L., et J. Lefèbvre: Analyse de la triple réaction cutanée au moyen d’un antagoniste de l’histamine. C. R. Soc. Biol. (Paris) 137, 316 (1943).

    CAS  Google Scholar 

  • Penna, M, A Illanes, M. Ubilla, and S. Musrca: Effect of histamine and of the anaphylactic reaction on isolated atria. Circulat. Res. 7, 521 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Peters, G. A., and B. T. Horton: Continuous intravenous administration of histamine: effect on the electrocardiogram and serum potassium. Amer. Heart J. 27, 845 (1944 a).

    Article  Google Scholar 

  • Peters, G. A., and B. T. Horton: Effect of continuous intravenous administration of histamine on basal metabolism of human beings. Proc. Centr. Soc. Clin. Res. 17, 65 (1944b).

    Google Scholar 

  • Peters, G. A., and B. T. Horton, and W. M. Boothby: Effect of continuous intravenous administration on basal metabolism in human beings. J. clin. Invest. 24, 611 (1945).

    Article  PubMed  CAS  Google Scholar 

  • Peters, G. A., and B. T. Horton, and W. M. Boothby: The effect of continuous intravenous administration of histamine on basal metabolism in human beings. Coll. Pap. Mayo Clin. Mayo Found. 37, 778 (1945).

    Google Scholar 

  • Peterson, R. D. A., and R. A. Goon: Morphology of vascular permeability. Lab. Invest. 11, 507 (1962).

    PubMed  CAS  Google Scholar 

  • Piemister, D. B., and J. Handy: Vascular properties of traumatized and laked blood. J. Physiol. (Lond.) 61, 155 (1927–1928).

    Google Scholar 

  • Pickering, G. W.: Observations on mechanism of headache produced by histamine. Clin. Sci. 1, 77 (1933).

    CAS  Google Scholar 

  • Pickering, G. W., and W. Hess: Vasodilatation in hands and feet in response to warming the body. Clin. Sci. 1, 213 (1933).

    Google Scholar 

  • Piiper, J., u. E. Schgrmeyer: Über den Einfluß von Doryl und Histamin auf die arteriovenösen Anastomosen in der Hundeextremität. Pflügers Arch. ges. Physiol. 261, 234 (1955).

    Article  CAS  Google Scholar 

  • Pittman, M.: Sensitivity of mice to histamine during respiratory infection by Hemophilus pertussis. Proc. Soc. exp. Biol. (N. Y.) 77, 70 (1951).

    CAS  Google Scholar 

  • Pittman, M., and F. G. Germuth: Some quantitative aspects of passive anaphylaxis in pertussisvaccinated mice. Proc. Soc. exp. Biol. (N. Y.) 87, 425 (1954).

    CAS  Google Scholar 

  • Popper, H.: Über Drosselvorrichtungen an Lebervenen. Klin. Wschr. 10, 2129 (1931).

    Article  Google Scholar 

  • Rabe, F.: Die Reaktion der Kranzgefäße auf Arzneimittel. Z. exp. Path. Ther. 11, 175 (1912).

    Google Scholar 

  • Ramanamanjary, W.: Action des antihistaminiques sur les effects tensionnels de l’histamine chez le lapin. C. R. Soc. Biol. 138, 480 (1944).

    CAS  Google Scholar 

  • Ramsdell, S. G.: The use of trypan blue to demonstrate the immediate skin reaction in rabbits and guinea pigs. J. Immunol. 15, 305 (1928).

    Google Scholar 

  • Ranson, S. W., L. R. Faubion, and C. J. Ross: Vasodilator mechanisms IV. The infra-arterial injection of histamine. Amer. J. Physiol. 64, 311 (1923).

    Google Scholar 

  • Renkin, E. M., and J. R. Pappenheimer: Wasserdurchlässigkeit und Permeabilität der Capillarwände. Ergebn. Physiol. 49, 59 (1957).

    Article  PubMed  CAS  Google Scholar 

  • Rich, A. R.: Condition of the capillaries in histamine shock. J. exp. Med. 33, 287 (1921).

    Article  PubMed  CAS  Google Scholar 

  • Rigdon, R. H.: Capillary permeability in areas of inflammation produced by xylene. Arch. Surg. 41, 101 (1940).

    Article  CAS  Google Scholar 

  • Rigdon, R. H.: Observations on effect of histamine phosphate on capillary permeability and inflammation. J. Lab. clin. Med. 27, 1554 (1941–1942).

    Google Scholar 

  • Robinson, R. L., and K. E. Jocnmi: Histamine and anaphylaxis on adrenal medullary secretion in dogs. Amer. J. Physiol. 199, 429 (1960).

    PubMed  CAS  Google Scholar 

  • Rocha E Silva, M.: Anaphylaxis in the rabbit. J. Immunol. 38, 333 (1940 a).

    Google Scholar 

  • Rocha E Silva, M.: Kallikrein and histamine Nature (Lond.) 145, 591 (1940b).

    Google Scholar 

  • Rocha E Silva, M.: Histamina e Anafilaxia. Sao Paulo: Edigraf Ltda. 1946.

    Google Scholar 

  • Rocha E Silva, M.: Histamine. Its Role in Anaphylaxis and Allergy. Springfield, Ill.: Charles C. Thomas 1955.

    Google Scholar 

  • Rocha E Silva, M., and A. Antonio: Release of bradykinin and the mechanism of production of a “thermic edema (45° C)” in the rat’s paw. Med. exp. (Basel) 3, 371 (1960).

    Article  Google Scholar 

  • Rocha E Silva, M., U. O. G. Bier: Untersuchungen über Entzündungen. II. Virchows Arch. path. Anat. 303, 337 (1939).

    Google Scholar 

  • Rocha E Silva, M., and C. A. Dragstedt: Observations on the trypan blue capillary permeability test in rabbits. J. Pharmacol. exp. Ther. 73, 405 (1941).

    Google Scholar 

  • Rose, B.: Production of symptoms by subcutaneous injection of histamine without increase of the blood histamine. Science 92, 454 (1940).

    Article  PubMed  CAS  Google Scholar 

  • Rose, B., and J. S. L. Browne: Distribution and rate of disappearance of intravenously injected histamine in rat. Amer. J. Physiol. 124, 412 (1938).

    CAS  Google Scholar 

  • Rose, B., and J. S. L. Browne: The effect of adrenalectomy on the histamine content of the tissues of the rat. Amer. J. Physiol. 131, 589 (1941).

    CAS  Google Scholar 

  • Rose, B., and S. Karady: Histamine metabolism in the adrenalectomized rat. Amer. J. Physiol. 126, P 614 (1939).

    Google Scholar 

  • Rössler, R.: Über experimentelle Herzschädigung durch Koronargefäßverengerung und ihre Beeinflussung durch Pharmaka. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 153, 1 (1930).

    Google Scholar 

  • Rössler, R., and W. Pascual: The coronary circulation in the isolated perfused heart. J. Physiol. (Lond.) 74, 1 (1932).

    Google Scholar 

  • Rothlin, E.: Uber die Einwirkung des Milzextraktes (Lienins) auf die Tätigkeit des Froschherzens in situ und des isolierten Säugetierherzens. Pflügers Arch. ges. Physiol. 185, 111 (1920).

    CAS  Google Scholar 

  • Rothlin, E., et R. Gundlach: Etude expérimentale de l’influence de l’histamine sur la sécrétion gastrique. Arch. in Physiol. 17, 59 (1921).

    Google Scholar 

  • Rowley, D. A., and E. P. Benditt: 5-hydroxytryptamine and histamine as mediators of the vascular injury produced by agents which damage mast cells in rats. J. exp. Med. 103, 399 (1956). „

    Google Scholar 

  • Rowleyrühl, A.: Uber Herzinsuffizienz durch Histamin. Naunyn-Schmiedeberg’s Arch. exp. Pathol. Pharmak. 145, 255 (1929).

    Google Scholar 

  • Rowleyrühl, A.: Über Gefäßinsuffizienz. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak 148, 24 (1930).

    Google Scholar 

  • Schachter, M.: Bradykinin and other capillary active factors. In: Symposium on Bradykinin,1st Int. Pharmacological Meeting (1961). Biochem. Pharmacol. 10, 87 (1962).

    CAS  Google Scholar 

  • Schafer, R. W.: Significance of induced synthesis of histamine in physiology and pathology. Chemotherapia 3, 128 (1961).

    Article  Google Scholar 

  • Schenk, P.: Über die Wirkungsweise des ß-imidazoläthylamins (Histamin) auf den menschlichen Organismus. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 89, 332 (1921).

    CAS  Google Scholar 

  • Schilf, E.: Über die Wirkung von Atropin und Histamin (nach vorhergehender Atropingabe) auf die Gefäße des Hundes. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 126, 37 (1927).

    CAS  Google Scholar 

  • Schmidt, C. F., and J. P. Hendrix: Cit. in Virno (1956). Ass. Res. nerv. Dis. Proc. 18, 229 (1937).

    CAS  Google Scholar 

  • Schneider, M., u. D. Schneider: Untersuchungen über die Regulierung der Gehirndurch- blutung. I. Mitt. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 175, 606 (1934).

    Article  CAS  Google Scholar 

  • Schneider, M., u. D. Schneider: Untersuchungen über die Regulierung der Gehirndurchblutung. II. Mitt. Einwirkung verschiedener Pharmaka auf die Gehirndurchblutung. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 175, 640 (1934).

    Article  CAS  Google Scholar 

  • Schretzenmayr, A.: Über die regulatorische Bedeutung der großen Arterien. II. Adenosinphosphorsäure, Histamin, Padutin und Tonephin. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 176, 160 (1934).

    CAS  Google Scholar 

  • Schröder, W.: Zit. in Paper U. E. Schümeyer (1955). Verh. dtsch. Ges. Kreisl.-Forsch. 18, 289 (1952).

    Google Scholar 

  • Selye, H.: The alarm reaction. Can. med. Ass. J. 34, 706 (1936).

    Google Scholar 

  • Selye, H.: The significance of the adrenal glands for adaptation. Arch. in Pharmacodyn. 55, 431 (1937).

    Google Scholar 

  • Selye, H.: First Annual Report on Stress. Montreal: Acta Inc., Med. Publ. 1951.

    Google Scholar 

  • Selye, H.: The stress of life. New York: McGraw Hill 1956.

    Google Scholar 

  • Selye, H.: Stress and cardiovascular disease. Wld-Wide Abstr. gen. Med. 4, 8 (1961).

    CAS  Google Scholar 

  • Sevitt, S.: Early and delayed edema and increase in capillary permeability after burns of the skin. J. Path. Bact. 75, 27 (1958).

    Article  PubMed  CAS  Google Scholar 

  • Sharpey-Schafer, E. P.: Venous tone. Brit. med. J. 1961 II, 1589.

    Google Scholar 

  • Sharpey-Schafer, E. P., and A. D. Macdonald: The actions of extracts of the posterior lobe of the pituitary body on the pulmonary circulation. Quart. J. exp. Physiol. 16, 251 (1926).

    CAS  Google Scholar 

  • Sicuteri, F., M. Ficini, R. Monfardini e M. Ricci: Cefalea sperimentale da istamina; studi sulle modificazioni sfigmiche del circolo esocranico nel soggetto normale. Settim. med. 45, 21 (1957).

    Google Scholar 

  • Silver, A., I. E. Steck, and C. I. Reed: A study of the effects of vitamin D on capillary permeability by the use of the dye T-1824. J. Lab. clin. Med. 29, 48 (1944).

    CAS  Google Scholar 

  • Simonds, J. P.: A study of the simultaneous changes in blood pressure in the carotid artery and jugular and portal veins in anaphylactic and peptone shock in the dog. Amer. J. Physiol. 65, 512 (1923).

    Google Scholar 

  • Simonds, J. P., and W. W. Brandes: Anaphylactic shock and mechanical destruction of the hepatic veins in the dog. J. Immunol. 13, 1 (1927).

    Google Scholar 

  • Slater, I. H., and P. E. Dresel: The pressor effect of histamine after autonomic ganglionic blockade. J. Pharmacol. exp. Ther. 105, 101 (1952).

    PubMed  CAS  Google Scholar 

  • Smith, D. J.: In vitro action of cortisone on vasoconstriction due to histamine. Proc. Soc. exp. Biol. (N. Y.) 77, 534 (1951).

    CAS  Google Scholar 

  • Smith, M. I.: Studies on experimental shock with special reference to its treatment. J. Pharmacol. exp. Ther. 32, 465 (1928).

    CAS  Google Scholar 

  • Snyder, C. D.: Recent advances in knowledge of the liver. Physiol. Rev. 22, 54 (1942).

    Google Scholar 

  • Sollmann, T., and A. J. Gilbert: Reaction of carotid arteries of small animals. J. Pharmacol. exp. Ther. 62, 236 (1938).

    CAS  Google Scholar 

  • Sollmann, T., and J. D. Pilcher: Endermic reaction. J. Pharmacol. exp. Ther. 9, 309 (1917).

    CAS  Google Scholar 

  • Solotorovsxy, M., and S. Winsten: Anaphylaxis in mouse produced with crystalline bovine albumin. J. Immunol. 71, 296 (1953).

    Google Scholar 

  • Sollmann, T., and J. D. Pilcher: Inhibition of fatal anaphylactic shock in mouse with cortisone. J. Immunol. 72, 177 (1954).

    Google Scholar 

  • Sparrow, E. M., and P. L. Wilhelm: Species differences in susceptibility to capillary permeability factors; histamine, 5-HT and compound 48/80. J. Physiol. (Lond.) 135, 51 (1957).

    Google Scholar 

  • Spector, W. G.: The role of some higher peptides in inflammation. J. Path. Bact. 63, 93 (1951).

    Article  PubMed  CAS  Google Scholar 

  • Spector, W. G.: Mediation of altered capillary permeability in acute inflammation. J. Path. Bact. 72, 367 (1956).

    Article  CAS  Google Scholar 

  • Spector, W. G.: Substances which affect capillary permeability. Pharmacol. Rev. 10, 475 (1958).

    PubMed  CAS  Google Scholar 

  • Spector, W. G., and D. A. Willoughby: Experimental suppression of increased capillary permeability in thermal burns in rats. Nature (Lond.) 182, 949 (1958).

    Article  CAS  Google Scholar 

  • Spector, W. G., and D. A. Willoughby: Experimental suppression of the acute inflammatory changes of thermal injury. J. Path. Bact. 78, 14 (1959).

    Article  Google Scholar 

  • Starling, E. H.: On the absorption of fluids from the connective tissue spaces. J. Physiol. (Loud.) 19, 312 (1895–1896).

    Google Scholar 

  • Starling, E. H.: The fluids of the body. Chicago: Univ. Chicago Press 1909.

    Google Scholar 

  • Staub, A. M.: Recherches sur quelques bases synthétiques antagonistes de l’histamine. I. Ann Inst. Pasteur 63, 400 (1939).

    CAS  Google Scholar 

  • Staub, H., u. W. Grassmann: Uber die Wirkungsgrenze einiger Gifte am isolierten Säugetier-herzen. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 154, 317 (1930).

    Article  CAS  Google Scholar 

  • Stead, E. A., and J. V. Warren: The effect of the injection of histamine into the brachial artery on the permeability of capillaries of the forearm and hand. J. clin. Invest. 23, 279 (1944).

    Article  PubMed  CAS  Google Scholar 

  • Symposium on The Mechanism of Inflammation. Edit. G. Jasmin and A. Robert. Montreal: Acta Inc., Medical Publishers 1953.

    Google Scholar 

  • Szabó, G., u. S. Magyar: Die Wirkung der Sympathicusblockade im Histaminschock. Z. ges. exp. Med. 135, 193 (1961).

    Article  Google Scholar 

  • Szczygielski, J.: Die adrenalinabsondernde Wirkung des Histamins und ihre Beeinflussung durch Nikotin. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 166, 319 (1932).

    Google Scholar 

  • Thomas, W. D., and H. E. Essex: Observations on hepatic venous circulation with special reference to the sphyncteric mechanism. Amer. J. Physiol. 158, 303 (1949). TöRö, J.: (1942). Cit. in Jancsó (1961).

    Google Scholar 

  • Trendelenburg, U.: The action of histamine and 5-hydroxytryptamine on isolated mammalian atria. J. Pharmacol. exp. Ther. 130, 450 (1960).

    PubMed  CAS  Google Scholar 

  • Trendelenburg, U.: The pressor response of the cat to histamine and pilocarpine. J. Pharmacol. exp. Ther. 131, 65 (1961).

    PubMed  CAS  Google Scholar 

  • Tribe-Oppenheimer, E.: Studies on the so-called heart hormone. Amer. J. Physiol. 90, 656 (1929).

    Google Scholar 

  • Tripod, J., E. Wirz et R. Meier: Influence de l’histamine sur l’activité cardiaque du chat. Arch. int. Pharmacodyn. 88, 51 (1951).

    CAS  Google Scholar 

  • Truex, R. E.: Chromaffin tissue of the sympathetic ganglia and heart. Anat. Rec. 108, 687 (1950).

    Article  PubMed  CAS  Google Scholar 

  • Underhill, F. P., and S. C. Roth: The influence of water deprivation, pilocarpin, and histamine upon changes in blood concentration in the rabbit. J. biol. Chem. 54, 607 (1922).

    CAS  Google Scholar 

  • Ungar, G.: Les substances histaminiques et la transmission chimique de l’influx nerveux. Paris: Hermann et Cie., Éditeurs 1937.

    Google Scholar 

  • Vallery-Radot, P.: L’anaphylaxie humaine et expérimentale. Paris: Masson et Cie. 1937.

    Google Scholar 

  • Vallery-Radot, P.: Précis des Maladies Allergiques 18. Paris: Flammarion 1949.

    Google Scholar 

  • Vanremoortere, E., H. Mazzella et J. Lecomte: Action de l’histamine sur le débit coronarien du coeur isolé du lapin, en fibrillation ventriculaire. Arch. int. Physiol. 59, 471 (1951).

    CAS  Google Scholar 

  • Vaughan-Williams, E M: The action of quinidine, acetylcholine and anaphylaxis interpreted from simultaneous and intracellular potentials in the heart. In: The Scientific Basis of Medicine. Ann. Rev. University of London. The Athlone Press 302 (1961).

    Google Scholar 

  • Viotti, C.: Action de l’histamine sur le coeur et importance de l’atropine à cet égard. C. R. Soc. Biol. (Paris) 91, 1085 (1924).

    CAS  Google Scholar 

  • Virno, M., S. B. Gertner, and D. Bovet: Action of histamine on the jugular venous pressure and cerebral circulation of the dog. Effects of antihistaminic drugs (pyrilamine and chlorpheniramine) and a histamine liberating agent (48/80 B. W.). J. Pharmacol. exp. Ther. 118, 63 (1956).

    PubMed  CAS  Google Scholar 

  • Wakim, K. G., G. A. Peters, J. C. Terrier, and B. T. Horton: Effects of intravenously administered histamine on peripheral circulation in man. J. Lab. clin. Med. 34, 380 (1949).

    PubMed  CAS  Google Scholar 

  • Waud, R. A.: Viscosity of the blood in histamine shock. Amer. J. Physiol. 84, 563 (1928).

    Google Scholar 

  • Weiser, R. S., O. J. Golub. and D. M. Hamre: Studies on anaphylaxis in the mouse J. infect. Dis. 68, 97 (1941).

    Google Scholar 

  • Weiss, S., L. B. Elias, and G. P. Ross: Bodily responses in man during the continuous intravenous administration of histamine. Amer. J. Physiol. 90 551 (1929 a).

    Google Scholar 

  • Weiss, S., G. P. Robb, and H. L. Blumgart: The velocity of blood flow in health and disease as measured by the effect of histamine on the minute vessels. Amer. Heart J. 4, 664 (1929b).

    Article  Google Scholar 

  • Weiss, S., G. P. Robb, and L. B. Ellis: The systemic effects of histamine in man; with special reference to the responses of the cardiovascular system. Arch. intern. Med. 49, 360 (1932).

    Google Scholar 

  • Went, I., u. E. Varga: Experimentelle Untersuchungen über die chemische Gegenregulation des Blutdruckes. Acta physiol. Acad. Sci. hung. 3, 377 (1952).

    CAS  Google Scholar 

  • Went, I., u. E. Varga, E. Szücs u. O. Feuer: Eine Analyse der sympathomimetischen Wirkung des Histamins an isolierten Säugetierherzpräparaten. Acta physiol. Acad. Sci. hung. 5, 121 (1954).

    CAS  Google Scholar 

  • Went, S., u. K. Lissak: Histamin und Proteinwirkung am normalen und sensibilisierten Meerschweinchenherz. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 179, 609 (1935).

    Article  CAS  Google Scholar 

  • Went, S.,Wu. J. Martin: Über die Schockresistenz der weißen Ratte. Naunyn-Schmiedeberg’s Arch. exp. Path. Pharmak. 191, 545 (1939).

    Google Scholar 

  • Went, S.,WE. Varga, E. Szücs u. O. Feuer: Über eine „sympathomimetische“ Wirkung des Histamins. Naunyn-Schmiedeberg’s Arch. exp. Pharmak. 215, 129 (1952).

    CAS  Google Scholar 

  • White, T.: Some effects of histamine and two histamine metabolites on the cat’s brain. J. Physiol. (Lund.) 159, 198 (1961).

    CAS  Google Scholar 

  • Wiggers, C. J.: Physiology of Shock. New York: The Commonwealth Fund. 1950.

    Google Scholar 

  • Wilcox, H. B., and E. C. Andrus: Anaphylaxis in the isolated heart. J. exp. Med. 67, 169 (1938).

    Article  PubMed  CAS  Google Scholar 

  • Wilcox, H. B., and B. C. Seegal: Influence of an ethylenediamine derivative on histamine intoxication and anaphylactic shock in the intact guinea pig and the isolated guinea pig heart. J. Immunol. 44, 219 (1942).

    CAS  Google Scholar 

  • Wilhelm, D L: The mediators of increased vascular permeability in inflammation. Pharmacol. Rev. 14, 251 (1962).

    PubMed  CAS  Google Scholar 

  • Winternitz, M. C., and A. D. Hirschfelder: Studies upon experimental pneumonia in rabbits. J. exp. Med. 17, 657 (1913).

    Article  PubMed  CAS  Google Scholar 

  • Woodbury, R. A.: Influence of epinephrine and atropine on pulmonary pressor action of histamine. J. Pharmacol. exp. Ther. 86, 78 (1946).

    Google Scholar 

  • Woodbury, R. A., and W. F. Hamilton: Effect of histamine on pulmonary blood pressure of various animals with and without anesthesia. J. Pharmacol. exp. Ther. 71, 293 (1941).

    CAS  Google Scholar 

  • Wybauw, L.: Transmission humorale de la vaso-dilatation provoquée par l’excitation du bout périphérique des racines postérieures lombaires chez le chat. C. R. Soc. Biol. (Paris) 123, 524 (1937).

    Google Scholar 

  • Wybauw, L.: Contribution à l’étude du rôle vaso-moteur et trophique des nerfs sensitifs. Arch. int. Physiol. 46, 293 (1938).

    Google Scholar 

  • Wyman, L. C., and C. T. Suden: The blood volume of the rat in suprarenal insufficiency, anaphylactic shock and histamine shock. Amer. J. Physiol. 93, 700 (1930).

    Google Scholar 

  • Zweifach, B. W.: Structure and reactions of small blood vessels in amphibia. Amer. J. Anat. 60, 473 (1937).

    Article  Google Scholar 

  • Zweifach, B. W.: The structural basis of permeability and other functions of blood capillaries. Cold Spr. Harb. Symp. quant. Biol. 8, 216 (1940).

    CAS  Google Scholar 

  • Zweifach, B. W.: Structural makeup of the capillary wall. Ann N Y Acad. Sci. 61, 670 (1955).

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. M. Rocha e Silva
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Mauricio Rocha e Silva

Rights and permissions

Reprints and permissions

Copyright information

© 1966 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Rocha e Silva, M. (1966). Action of Histamine upon the Circulatory Apparatus. In: Rocha e Silva, M. (eds) Histamine and Anti-Histaminics. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 18 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12016-3_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-12016-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-12018-7

  • Online ISBN: 978-3-662-12016-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation