Summary
A number of observations show that intestinal sucrase is closely located, in the brush borders, to the sugar transport system.
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1.
Both intestinal sucrase (Semenza et al. 1963, 1964; cf. also Crane Kinter 1961) and sucrase (Miller and Crane 1961;. Doell, Rosen and Kretchmer 1963) are located in the brush borders.
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2.
The glucose moiety of sucrose is better absorbed than free glucose (Fridhandler and Quastel 1955; Miller and Crane 1961).
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3.
The glucose moiety of sucrose is absorbed directly and is not previously released into the medium (as shown by the fact that the presence of glucose oxidase in the medium does not reduce the absorption of glucose from sucrose, Miller and Crane 1961).
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References
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Semenza, G. (1967). Role of Intestinal Disaccharidases in Sugar Transport. In: Bolis, L., Capraro, V., Porter, K.R., Robertson, J.D. (eds) Symposium on Biophysics and Physiology of Biological Transport. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25134-8_15
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