Abstract
Because the relation of water fluoridation to dental caries has been so thoroughly studied and reviewed, it is not the intention of the author to discuss this subject in detail, but to present a brief outline, pertinent points and some new information. The main purpose of this discussion is to review the vast recent literature on the clinical aspects of fluoride supplementation and topically applied fluoride, and to bring up to date available basic information concerning the chemistry of fluoride and tooth mineral, and the mechanism of action of fluoride in inhibiting caries.
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References
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Brudevold, F. (1966). The Role of Fluorides in Tooth Chemistry and in the Prevention of Dental Caries. In: Smith, F.A. (eds) Pharmacology of fluorides. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25198-0_4
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