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Function of Thin Segments of Henle’s Loop

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Nephrology

Abstract

It is well known that the renal medulla plays an important role in the generation of concentrated urine, which is critical in the maintenance of body fluid osmolality. Since the proposal of the operation of countercurrent systems in the renal medulla by Kuhn and his associates [1–3], it has been widely accepted that the loop structures of the nephron in the renal medulla are essential for the generation and maintenance of a steep osmotic gradient along the axis of the renal medulla. However, the detailed mechanisms by which a steep osmotic gradient is generated by the countercurrent multiplication system remain to be established.

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Author information

Authors and Affiliations

  1. Department of Pharmacology, Jichi Medical School, Minamikawachi, Kawachi, Tochigi, 329-04, Japan

    Masashi Imai, Koji Yoshitomi, Kaoru Tabei & Shigeru Koyama

  2. Department of Pediatrics, Tohoku University, Sendai 980, Japan

    Yoshiaki Kondo

  3. Departments of Molecular Physiology and Cell Biology, National Cardiovascular Center, Osaka, 565, Japan

    Junichi Taniguchi & Chizuko Koseki

  4. Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, 431-31, Japan

    Taisuke Isozaki

Authors
  1. Masashi Imai
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  2. Koji Yoshitomi
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  4. Junichi Taniguchi
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  5. Chizuko Koseki
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  8. Shigeru Koyama
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

    Michinobu Hatano M.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

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© 1991 Springer Japan

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Imai, M. et al. (1991). Function of Thin Segments of Henle’s Loop. In: Hatano, M. (eds) Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35158-1_3

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  • DOI: https://doi.org/10.1007/978-3-662-35158-1_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-70074-6

  • Online ISBN: 978-3-662-35158-1

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