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Effects of Hormone Replacement Therapy on Skin Viscoelasticity During Climacteric Aging

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Skin, Mucosa and Menopause

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Abstract

During perimenopause, the skin and a series of other organs become altered as prominent sex hormone declines. The natural climacteric is associated with a decline in functional properties of various tissues including viscoelasticity of the dermal connective tissue. There are many ways for assessing in vivo skin viscoelasticity, and the various procedures frequently measure distinct physical characteristics. The suction method has been selected by a majority of investigators looking at dermal functional changes during climacteric. Some women benefit from oral hormone replacement therapy (HRT) or transdermal estrogen therapy (TET) for controlling some unpleasant climacteric changes (osteoporosis, vasomotor instability, skin withering, dermal depletion in versican-hyaluronic acid, etc.). In particular, the hormonal repair exhibits some preventive and corrective effects in the functional decline of the dermal physical properties.

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Authors and Affiliations

  1. Department of Dermatopathology, University Hospital of Liège, Boulevard de l’Hôpital, Liège, 4000, Belgium

    Gérald E. Piérard MD, PhD, Trinh Hermanns-Lê MD, PhD & Claudine Piérard-Franchimont MD, PhD

  2. Telecommunications and Imaging Laboratory, Montefiore Institute, Intelsig, University of Liège, Liège, Belgium

    Sébastien Piérard MD, PhD

Authors
  1. Gérald E. Piérard MD, PhD
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  2. Trinh Hermanns-Lê MD, PhD
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  3. Sébastien Piérard MD, PhD
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  4. Claudine Piérard-Franchimont MD, PhD
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Correspondence to Gérald E. Piérard MD, PhD .

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Editors and Affiliations

  1. Procter & Gamble Co., Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Procter & Gamble Co., Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. School of Nursing, University of Washington, Seattle, Washington, USA

    Nancy Fugate Woods

  4. Department of Dermatology, University of California School of Medicine, San Francisco, California, USA

    Howard I. Maibach

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Piérard, G.E., Hermanns-Lê, T., Piérard, S., Piérard-Franchimont, C. (2015). Effects of Hormone Replacement Therapy on Skin Viscoelasticity During Climacteric Aging. In: Farage, M., Miller, K., Fugate Woods, N., Maibach, H. (eds) Skin, Mucosa and Menopause. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44080-3_8

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  • DOI: https://doi.org/10.1007/978-3-662-44080-3_8

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