Abstract
Anatomical reference brains are indispensable tools in human brain mapping, enabling the integration of multimodal data or the alignment of a series of adjacent histological brain sections into an anatomically realistic space. This study describes a robust and efficient method for an automatic 3D reconstruction of blockface images taken from postmortem brains during cutting as a prerequisite for high-quality 3D reconstruction of brain sections. The refinement technique used in this registration method is applicable for a broad range of pre-registered histological stacks.
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Schober, M. et al. (2015). Reference Volume Generation for Subsequent 3D Reconstruction of Histological Sections. In: Handels, H., Deserno, T., Meinzer, HP., Tolxdorff, T. (eds) Bildverarbeitung für die Medizin 2015. Informatik aktuell. Springer Vieweg, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46224-9_26
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DOI: https://doi.org/10.1007/978-3-662-46224-9_26
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