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Future Directions of Atherosclerosis Research and Translation into Clinical Application

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Inflammation and Atherosclerosis

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Abstract

Atherosclerosis, a disease of the large and medial arteries, is the primary cause of 3 heart disease, stroke and gangrene of the extremities. In westernized societies, it is 4 the underlying cause of about 50% of all deaths. Atherosclerosis is a multifactorial 5 disease induced by the effects of various risk factors on appropriate genetic 6 backgrounds. Many factors, such as hypercholesterolemia, modified lipoproteins, 7 hypertension, diabetes mellitus, infections, and smoking are identified as being 8 involved in the development of the disease [1].

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Author information

Authors and Affiliations

  1. Cardiovascular Division, King’s College London BHF Centre, 125 Coldharbour Lane, London, SE5 9NU, UK

    Qingbo Xu

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  1. Qingbo Xu
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Correspondence to Qingbo Xu .

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Editors and Affiliations

  1. Medical University Innsbruck, Peter-Mayr-Strasse 4 a, Innsbruck, 6020, Austria

    Georg Wick

  2. Laboratory of Autoimmunity, Division of Experimental Pathophysiology, Biocenter, Innsbruck Medical University, Schöpfstraße 41, Innsbruck, 6020, Austria

    Cecilia Grundtman

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Xu, Q. (2012). Future Directions of Atherosclerosis Research and Translation into Clinical Application. In: Wick, G., Grundtman, C. (eds) Inflammation and Atherosclerosis. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0338-8_30

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