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Bifurcations and Multistability in Periodically Stimulated Cardiac Cells

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Biosimulation in Biomedical Research, Health Care and Drug Development

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Abstract

Application of fractal dimensions, Lyapunov exponents, and other measures from dynamical systems theory to characterize the function of the heart has led to extended and quite vivid discussions about how to interpret the observed irregularity of the human heart beat [10]. It is generally accepted that the heart rhythm tends to become more regular with age, but it is also clear that certain conditions that predispose a person for heart failure are reflected in particular patterns of irregular heart beat.

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Authors and Affiliations

  1. Space Dynamics and Data Analysis Department, Space Research Institute, Russian Academy of Sciences, Moscow, Russia

    Elena Surovyatkina

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  1. Elena Surovyatkina
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Correspondence to Elena Surovyatkina .

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Editors and Affiliations

  1. , Department of Physics, Technical University of Denmark, Fysikvej Building 309, Kongens Lyngby, 2800, Denmark

    Erik Mosekilde

  2. , Department of Biomedical Sciences, Copenhagen University, Panum Institute, Copenhagen N, 2200, Denmark

    Olga Sosnovtseva

  3. , School of Pharmacy and Pharmaceutical Sc, University of Manchester, Oxford Road, Manchester, M13 9PT, U, United Kingdom

    Amin Rostami-Hodjegan

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Surovyatkina, E. (2011). Bifurcations and Multistability in Periodically Stimulated Cardiac Cells. In: Mosekilde, E., Sosnovtseva, O., Rostami-Hodjegan, A. (eds) Biosimulation in Biomedical Research, Health Care and Drug Development. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0418-7_12

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