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New concepts and tools in imaging for the study of neurodegenerative disease

  • Conference paper
Advances in Research on Neurodegeneration

Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 65))

Summary

Existing technologies permit the detection of changes in neurotransmitter and/or neuroreceptor expression. This may be useful for diagnosis, for monitoring disease progression, and for assessing the pathogenesis of complications associated with long-term treatment. Although the binding of [11C]raclopride to D2 receptors is subject to competition from endogenous dopamine, this can be exploited to estimate changes in synaptic levels of dopamine. Assessment of processes downstream to the receptor will require the development of new approaches.

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Authors and Affiliations

  1. Pacific Parkinson’s Research Centre, University of British Columbia, Vancouver Hospital & Health Sciences Centre, 2221 Wesbrook Mall, Vancouver, BC, Canada, V6T 2B5

    A. J. Stoessl, C. S. Lee & R. de la Fuente-Fernandez

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  1. A. J. Stoessl
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  2. C. S. Lee
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  3. R. de la Fuente-Fernandez
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Editor information

Editors and Affiliations

  1. Neurobiotec, Berlin, Federal Republic of Germany

    R. Horowski

  2. Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan

    Y. Mizuno

  3. Department of Neurology, The Mount Sinai Medical Center, New York, NY, USA

    C. W. Olanow

  4. Department of Neurology, University of Innsbruck, Innsbruck, Austria

    W. H. Poewe

  5. Department of Psychiatry, University of Würzburg, Würzburg, Federal Republic of Germany

    P. Riederer

  6. Neurodegenerative Disorders Centre, The University of British Columbia, Vancouver, B.C., Canada

    J. A. Stoessl

  7. Department of Pharmacology, Technion — Israel Institute of Technology, Haifa, Israel

    M. B. H. Youdim

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© 2003 Springer-Verlag Wien

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Stoessl, A.J., Lee, C.S., de la Fuente-Fernandez, R. (2003). New concepts and tools in imaging for the study of neurodegenerative disease. In: Horowski, R., et al. Advances in Research on Neurodegeneration. Journal of Neural Transmission. Supplementa, vol 65. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0643-3_9

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  • DOI: https://doi.org/10.1007/978-3-7091-0643-3_9

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83907-2

  • Online ISBN: 978-3-7091-0643-3

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