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Multimodal functional neuronavigation and intraoperative imaging

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Brain Mapping

Abstract

Neurosurgical resection techniques in glioma surgery have evolved from simple tumor debulking to a holistic concept which includes anatomy, function and metabolism both of tumor and adjacent brain parenchyma. Driven by the dichotomic aim not to induce neurological deterioration while attempting to achieve gross tumor resection, neurosurgeons have sought to improve surgical outcome with the help of modern image guided techniques. In this chapter the implementation of multimodal functional neuronavigation and intraoperative imaging in glioma surgery is described.

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References

  1. Basser PJ, Mattiello J, LeBihan D (1994) MR diffusion tensor spectroscopy and imaging. Biophys J 66: 259–267

    Article  PubMed  CAS  Google Scholar 

  2. Basser PJ, Pajevic S, Pierpaoli C, Duda J, Aldroubi A (2000) In vivo fiber tractography using DT-MRI data. Magn Reson Med 44: 625–632

    Article  PubMed  CAS  Google Scholar 

  3. Black PM, Moriarty T, Alexander III E, Stieg P, Woodard EJ, Gleason PL, Martin CH, Kikinis R, Schwartz RB, Jolesz FA (1997) Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery 41: 831–845

    Article  PubMed  CAS  Google Scholar 

  4. Branco DM, Suarez RO, Whalen S, O’shea JP, Nelson AP, da Costa JC, Golby AJ (2006) Functional MRI of memory in the hippocampus: Laterality indices may be more meaningful if calculated from whole voxel distributions. Neuroimage 32: 592–602

    Article  PubMed  Google Scholar 

  5. Duffau H, Capelle L, Denvil D, Sichez N, Gatignol P, Taillandier L, Lopes M, Mitchell MC, Roche S, Muller JC, Bitar A, Sichez JP, van Effenterre R (2003) Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients. J Neurosurg 98: 764–778

    Article  PubMed  Google Scholar 

  6. Duffau H, Denvil D, Capelle L (2002) Long term reshaping of language, sensory, and motor maps after glioma resection: a new parameter to integrate in the surgical strategy. J Neurol Neurosurg Psychiatry 72: 511–516

    PubMed  CAS  Google Scholar 

  7. Goebell E, Fiehler J, Ding XQ, Paustenbach S, Nietz S, Heese O, Kucinski T, Hagel C, Westphal M, Zeumer H (2006) Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients — a combined diffusion tensor imaging and 1H-MR spectroscopy study. Am J Neuroradiol 27: 1426–1431

    PubMed  CAS  Google Scholar 

  8. Grummich P, Kober H, Vieth J (1992) Localization of multi source magnetic brain activity using a spatial filter reconstruction. In: Dittmar A, Froment J (eds) Proc Satellite Symp on Neuroscience and Technology of the 14th Ann Int Conf of the IEEE Eng Med Biol Soc, Lyon, France

    Google Scholar 

  9. Grummich P, Kober H, Vieth J (1992) Localization of the underlying current of magnetic brain activity using spatial filtering. Biomed Eng 37: 158–159

    Google Scholar 

  10. Grummich P, Nimsky C, Pauli E, Buchfelder M, Ganslandt O (2006) Combining fMRI and MEG increases the reliability of presurgical language localization: a clinical study on the difference between and congruence of both modalities. Neuroimage 32: 1793–1803

    Article  PubMed  Google Scholar 

  11. Hall WA, Kowalik K, Liu H, Truwit CL, Kucharezyk J (2003) Costs and benefits of intraoperative MR-guided brain tumor resection. Acta Neurochir (Suppl 85): 137–142

    Article  CAS  Google Scholar 

  12. Hall WA, Liu H, Martin AJ, Pozza CH, Maxwell RE, Truwit CL (2000) Safety, efficacy, and functionality of high-field strength interventional magnetic resonance imaging for neurosurgery. Neurosurgery 46: 632–642

    Article  PubMed  CAS  Google Scholar 

  13. Hastreiter P, Rezk-Salama C, Nimsky C, Lürig C, Greiner G, Ertl T (2000) Registration techniques for the analysis of the brain shift in neurosurgery. Comput Graph 24: 385–389

    Article  Google Scholar 

  14. Hastreiter P, Rezk-Salama C, Soza G, Bauer M, Greiner G, Fahlbusch R, Ganslandt O, Nimsky C (2004) Strategies for brain shift evaluation. Med Image Anal 8: 447–464

    Article  PubMed  Google Scholar 

  15. Kamada K, Sawamura Y, Takeuchi F, Kawaguchi H, Kuriki S, Todo T, Morita A, Masutani Y, Aoki S, Kirino T (2005) Functional identification of the primary motor area by corticospinal tractography. Neurosurgery 56: 98–109

    Article  PubMed  Google Scholar 

  16. Kamada K, Todo T, Masutani Y, Aoki S, Ino K, Takano T, Kirino T, Kawahara N, Morita A (2005) Combined use of tractography-integrated functional neuronavigation and direct fiber stimulation. J Neurosurg 102: 664–672

    Article  PubMed  Google Scholar 

  17. Kinoshita M, Hashimoto N, Goto T, Kagawa N, Kishima H, Izumoto S, Tanaka H, Fujita N, Yoshimine T (2008) Fractional anisotropy and tumor cell density of the tumor core show positive correlation in diffusion tensor magnetic resonance imaging of malignant brain tumors. Neuroimage 43: 29–35

    Article  PubMed  CAS  Google Scholar 

  18. Kinoshita M, Yamada K, Hashimoto N, Kato A, Izumoto S, Baba T, Maruno M, Nishimura T, Yoshimine T (2005) Fiber-tracking does not accurately estimate size of fiber bundle in pathological condition: initial neurosurgical experience using neuronavigation and subcortical white matter stimulation. Neuroimage 25: 424–429

    Article  PubMed  Google Scholar 

  19. Kober H, Nimsky C, Vieth J, Fahlbusch R, Ganslandt O (2002) Co-registration of function and anatomy in frameless stereotaxy by contour fitting. Stereotact Funct Neurosurg 79: 272–283

    Article  PubMed  Google Scholar 

  20. Mori S, Crain BJ, Chacko VP, van Zijl PC (1999) Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 45: 265–269

    Article  PubMed  CAS  Google Scholar 

  21. Mori S, Van Zijl PC (2002) Fiber tracking: principles and strategies — a technical review. NMR Biomed 15: 468–480

    Article  PubMed  Google Scholar 

  22. Nabavi A, Black PM, Gering DT, Westin CF, Mehta V, Pergolizzi RS, Jr., Ferrant M, Warfield SK, Hata N, Schwartz RB, Wells WM, 3rd, Kikinis R, Jolesz FA (2001) Serial intraoperative magnetic resonance imaging of brain shift. Neurosurgery 48: 787–798

    PubMed  CAS  Google Scholar 

  23. Nimsky C, Ganslandt O, Fahlbusch R (2005) Comparing 0.2 tesla with 1.5 tesla intraoperative magnetic resonance imaging analysis of setup, workflow, and efficiency. Acad Radiol 12: 1065–1079

    Article  PubMed  Google Scholar 

  24. Nimsky C, Ganslandt O, Fahlbusch R (2006) Implementation of fiber tract navigation. Neurosurgery 58: ONS-292–304

    Article  Google Scholar 

  25. Nimsky C, Ganslandt O, Hastreiter P, Fahlbusch R (2001) Intraoperative compensation for brain shift. Surg Neurol 56: 357–365

    Article  PubMed  CAS  Google Scholar 

  26. Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, Sorensen AG, Fahlbusch R (2005) Intraoperative diffusion tensor imaging: shifting of white matter tracts during neurosurgical procedures — initial experience. Radiology 234: 218–225

    Article  PubMed  Google Scholar 

  27. Nimsky C, Ganslandt O, Hastreiter P, Wang R, Benner T, Sorensen AG, Fahlbusch R (2005) Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery. Neurosurgery 56: 130–138

    PubMed  Google Scholar 

  28. Nimsky C, Ganslandt O, Keller v B, Romstöck J, Fahlbusch R (2004) Intraoperative high-field strength MR imaging: implementation and experience in 200 patients. Radiology 233: 67–78

    Article  PubMed  Google Scholar 

  29. Nimsky C, Ganslandt O, Merhof D, Sorensen AG, Fahlbusch R (2006) Intraoperative visualization of the pyramidal tract by diffusion-tensor-imaging-based fiber tracking. Neuroimage 30: 1219–1229

    Article  PubMed  Google Scholar 

  30. Nimsky C, Ganslandt O, Von Keller B, Romstock J, Fahlbusch R (2004) Intraoperative high-field-strength MR imaging: implementation and experience in 200 patients. Radiology 233: 67–78

    Article  PubMed  Google Scholar 

  31. Nimsky C, Ganslandt O, Weigel D, Keller v B, Stadlbauer A, Akutsu H, Hammen T, Buchfelder M (2008) Intraoperative tractography and neuronavigation of the pyramidal tract. Jpn J Neurosurg 17: 21–26

    Google Scholar 

  32. Nimsky C, Grummich P, Sorensen AG, Fahlbusch R, Ganslandt O (2005) Visualization of the pyramidal tract in glioma surgery by integrating diffusion tensor imaging in functional neuronavigation. Zentralbl Neurochir 66: 133–141

    Article  PubMed  CAS  Google Scholar 

  33. Rachinger J, von Keller B, Ganslandt O, Fahlbusch R, Nimsky C (2006) Application accuracy of automatic registration in frameless stereotaxy. Stereotact Funct Neurosurg 84: 109–117

    Article  PubMed  Google Scholar 

  34. Roux FE, Boulanouar K, Lotterie JA, Mejdoubi M, LeSage JP, Berry I (2003) Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation. Neurosurgery 52: 1335–1345; discussion 1345–1337

    Article  PubMed  Google Scholar 

  35. Schreiber A, Hubbe U, Ziyeh S, Hennig J (2000) The influence of gliomas and nonglial space-occupying lesions on blood-oxygen-level-dependent contrast enhancement. Am J Neuroradiol 21: 1055–1063

    PubMed  CAS  Google Scholar 

  36. Stadlbauer A, Ganslandt O, Buslei R, Hammen T, Gruber S, Moser E, Buchfelder M, Salomonowitz E, Nimsky C (2006) Gliomas: histopathologic evaluation of changes in directionality and magnitude of water diffusion at diffusion-tensor MR imaging. Radiology 240: 803–810

    Article  PubMed  Google Scholar 

  37. Stadlbauer A, Nimsky C, Buslei R, Salomonowitz E, Hammen T, Buchfelder M, Moser E, Ernst-Stecken A, Ganslandt O (2007) Diffusion tensor imaging and optimized fiber tracking in glioma patients: Histopathologic evaluation of tumor-invaded white matter structures. Neuroimage 34: 949–956

    Article  PubMed  Google Scholar 

  38. Stadlbauer A, Nimsky C, Gruber S, Moser E, Hammen T, Engelhorn T, Buchfelder M, Ganslandt O (2007) Changes in fiber integrity, diffusivity, and metabolism of the pyramidal tract adjacent to gliomas: a quantitative diffusion tensor fiber tracking and MR spectroscopic imaging study. Am J Neuroradiol 28: 462–469

    PubMed  CAS  Google Scholar 

  39. Stieltjes B, Kaufmann WE, van Zijl PC, Fredericksen K, Pearlson GD, Solaiyappan M, Mori S (2001) Diffusion tensor imaging and axonal tracking in the human brainstem. Neuroimage 14: 723–735

    Article  PubMed  CAS  Google Scholar 

  40. Stippich C, Rapps N, Dreyhaupt J, Durst A, Kress B, Nennig E, Tronnier VM, Sartor K (2007) Localizing and lateralizing language in patients with brain tumors: feasibility of routine preoperative functional MR imaging in 81 consecutive patients. Radiology 243: 828–836

    Article  PubMed  Google Scholar 

  41. Sutherland GR, Kaibara T, Louw D, Hoult DI, Tomanek B, Saunders J (1999) A mobile high-field magnetic resonance system for neurosurgery. J Neurosurg 91: 804–813

    Article  PubMed  CAS  Google Scholar 

  42. Talos I, O’Donnell L, Westin CF, Warfield SK, Wells WM, 3rd, Yoo S, Panych L, Golby A, Mamata H, Maier S, Ratiu P, Guttmann C, Black PM, Jolesz F, Kikinis R (2003) Diffusion tensor and functional MRI fusion with anatomical MRI for image-guided neurosurgery. In: Ellis R, Peters T (eds) MICCAI 2003. Springer, Berlin Heidelberg, pp 407–415

    Google Scholar 

  43. Tharin S, Golby A (2007) Functional brain mapping and its applications to neurosurgery. Neurosurgery 60: 185–201; discussion 201–182

    Article  PubMed  Google Scholar 

  44. Thesen S, Heid O, Mueller E, Schad LR (2000) Prospective acquisition correction for head motion with image-based tracking for real-time fMRI. Magn Reson Med 44: 457–465

    Article  PubMed  CAS  Google Scholar 

  45. Wirtz CR, Bonsanto MM, Knauth M, Tronnier VM, Albert FK, Staubert A, Kunze S (1997) Intraoperative magnetic resonance imaging to update interactive navigation in neurosurgery: method and preliminary experience. Comput Aided Surg 2: 172–179

    PubMed  CAS  Google Scholar 

  46. Wu JS, Zhou LF, Hong XN, Mao Y, Du GH (2003) Role of diffusion tensor imaging in neuronavigation surgery of brain tumors involving pyramidal tracts. Zhonghua Wai Ke Za Zhi 41: 662–666

    PubMed  Google Scholar 

  47. Yingling CD, Ojemann S, Dodson B, Harrington MJ, Berger MS (1999) Identification of motor pathways during tumor surgery facilitated by multichannel electromyographic recording. J Neurosurg 91: 922–927

    Article  PubMed  CAS  Google Scholar 

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Ganslandt, O., Grummich, P., Nimsky, C. (2011). Multimodal functional neuronavigation and intraoperative imaging. In: Duffau, H. (eds) Brain Mapping. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0723-2_21

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  • DOI: https://doi.org/10.1007/978-3-7091-0723-2_21

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-0722-5

  • Online ISBN: 978-3-7091-0723-2

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