Summary
Diameter variations of pial vessels as well as mean arterial pressure (MAP), heart rate, body temperature and intracranial pressure (ICP) were continuously monitored before and after intravenous administration of 15μg • kg−1 dihydroergotamine (DHE) in six anaesthetized cats. Pial veins (138.3 ± 8.1µm; n = 36) showed no or minor calibre changes after injection whereas pial arteries (105.0 ± 7.01.im; n = 36) dilated in three cats and constricted in two. While MAP remained constant, heart rate decreased by 10.7 ± 3.1% from resting values. No significant change was observed in ICP. Thus, DHE does not constrict cerebral veins in anaesthetized cats.
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© 1983 Springer-Verlag Wien
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Sayama, I., Auer, L.M., Johansson, B.B. (1983). Effect of Intravenous Dihydroergotamine on Cat Pial Veins and Intracranial Pressure. In: Auer, L.M., Loew, F. (eds) The Cerebral Veins. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4124-3_34
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DOI: https://doi.org/10.1007/978-3-7091-4124-3_34
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-4126-7
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