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Effect of Intravenous Dihydroergotamine on Cat Pial Veins and Intracranial Pressure

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The Cerebral Veins

Summary

Diameter variations of pial vessels as well as mean arterial pressure (MAP), heart rate, body temperature and intracranial pressure (ICP) were continuously monitored before and after intravenous administration of 15μg • kg−1 dihydroergotamine (DHE) in six anaesthetized cats. Pial veins (138.3 ± 8.1µm; n = 36) showed no or minor calibre changes after injection whereas pial arteries (105.0 ± 7.01.im; n = 36) dilated in three cats and constricted in two. While MAP remained constant, heart rate decreased by 10.7 ± 3.1% from resting values. No significant change was observed in ICP. Thus, DHE does not constrict cerebral veins in anaesthetized cats.

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© 1983 Springer-Verlag Wien

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Sayama, I., Auer, L.M., Johansson, B.B. (1983). Effect of Intravenous Dihydroergotamine on Cat Pial Veins and Intracranial Pressure. In: Auer, L.M., Loew, F. (eds) The Cerebral Veins. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4124-3_34

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  • DOI: https://doi.org/10.1007/978-3-7091-4124-3_34

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-4126-7

  • Online ISBN: 978-3-7091-4124-3

  • eBook Packages: Springer Book Archive

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