Zusammenfassung
Die Erfolgsraten nach einer „Herz-Lungen-Wiederbelebung“(HLW) sind trotz wesentlicher Verbesserungen der Notfallmedizin im organisatorischen Bereich noch immer mäßig. Auch der enorme Aufwand der „HLW-Aktionen“ (= Ausbildung von Laien in Herz-LungenWiederbelebung) hat die klinische und epidemiologische Situation nicht wesentlich ändern können [1, 2]. Der limitierende Faktor ist nach wie vor die Vulnerabilität des Zentralnervensystems. Deshalb wurde 1970 der Begriff der „Cardio-Pulmonalen-Reanimation“(CPR) auf „Cardio-Pulmonale-Cerebrale-Reanimation“(CPCR) erweitert [1].
Derzeitige Forschungen am IRRC Pittsburg/USA.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Safar P, Bircher N (1988) Cardiopulmonary Cerebral Resuscitation. Saunders, Philadelphia
Safar P (1988) Resuscitation from clinical death: pathophysiologic limits and therapeutic potentials. Crit Care Med 16: 923–941
Brain Resuscitation Clinical Trial I Study Group (1986) Randomized clinical study of thiopental loading in comatose survivors of cardiac arrest. N Engl J Med 314: 397–403
Negovsky VA, Gurvitch AM, Zolotokrylina ES (1983) Prostresuscitation Disease. Elsevier, Amsterdam
Safar P (1986) The pathophysiology of dying and reanimation. In: Schwartz G, Safar P et al. (eds) Principals and Practice of Emergency Medicine ( 2nd ed ). Saunders, Philadelphia
Safar P, Sterz F, Leonov Y, Radovsky A, Tisherman S, Oku K (1989) Systematic development of cerebral resuscitation after cardiac arrest. Three promising treatments: cardiopulmonary bypass, hypertensive hemodilution, and mild hypothermia. In: Baethmann A (ed) Causes and Mechanisms of Secondary Brain Damage. Springer, Berlin Heidelberg New York Tokyo (in press)
Vaagenes P, Safar P, Diven W, Moosy J, Rao G, Cantadore R, Kelsey S (1988) Brain enzyme levels in CSF after cardiac arrest and resuscitation in dogs. Markers of damage and predictors of outcome. J Cereb Blood Flow Metab 8: 262
Leonov Y, Sterz F, Safar P, Radovsky A, Oku K, Tisherman S, Stezoski SW (1989) Mild hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J Cereb Blood Flow Metab (in press)
Safar P, Abramson NA, Angelos M, Cantadore R, Leonov Y, Levine R, Pretto E, Reich H, Sterz F, Stezoski SW, Tisherman S (1989) Emergency cardiopulmonary bypass for resuscitation after from prolonged cardiac arrest. Am J Emerg Med (in press)
Gisvold SE, Safar P, Rao G, Moosy J, Kelsey S, Alexander H (1984) Multifaceted therapy after global brain ischemia in monkeys. Stroke 15 (5): 803–812
Leonov Y, Sterz F, Safar P, Reich H, Stezoski W, Alexander H (1988) Effect on neurologic outcome after prolonged cardiac arrest in dogs, of post-insult hypothermia by cardiopulmonary bypass. Preliminary results. Anesthesiology 69 (3A): A 845 (Abstract)
Wolfson SK, Safar P, Reich H, Clark J, Gur D (1980) Multifocal, dynamic cerebral hypoperfusion after prolonged cardiac arrest in dogs, measured by the stable Xenon-CT technique. Crit Care Med 16: 390 (Abstract)
Sterz F, Safar P, Leonov Y, Johnson D, Latchaw R, Hecht St, Oku K (1989) Cerebral multifocal hypoperfusion after cardiac arrest in dogs, mitigated by hypertension and hemodilution. Ann Emerg Med 18: 468 (Abstract)
Oku K, Safar P, Leonov Y, Sterz F, Tisherman S, Latchaw R, Johnson D, Stezoski W, Alexander H (1989) Multifocal cerebral perfusion failure after cardiac arrest in dogs, monitored by stabel-Xe enhanced CT method. Stroke (Abstract) (in press)
Oku K, Safar P, Leonov Y, Sterz F, Tishermann S, Obrist W, Stezoski W, Alexander H (1989) Changes of cerebral vs systemic metabolism after cardiac arrest in dogs. Stroke (Abstract), (in press)
Safar P, Stezoski SW, Nemoto E (1976) Amelioration of brain damage after 12 minutes’ cardiac arrest in dogs. Arch Neurol 33: 91–95
Leonov Y, Sterz F, Safar P, Oku K, Tishermann S, Johnson D, Latchaw R (1989) Hypertension (HT) and hemodilution (HD) after ventricular fibrillation (VF) cardiac arrest (CA) mitigate cerebral multifocal hypoperfusion and brain damage. 6th World Congress on Emergency and Disaster Medicine, September 10–15 (Abstract)
Tisherman SA, Safar P, Peitzman AB, Sterz F, Oku K (1989) Deep hypothermic circulatory arrest during resuscitation from exanguination hemorrhage. J Trauma (Abstract), (in press)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag/Wien
About this chapter
Cite this chapter
Sterz, F., Safar, P., Leonov, Y., Oku, K., Tisherman, S. (1990). Cardiopulmonale cerebrale Reanimation. In: Deutsch, E., et al. Neurologische Probleme des Intensivpatienten. Intensivmedizinisches Seminar, vol 2. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9078-4_23
Download citation
DOI: https://doi.org/10.1007/978-3-7091-9078-4_23
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82178-7
Online ISBN: 978-3-7091-9078-4
eBook Packages: Springer Book Archive