Abstract
A newly discovered subset of T helper cells, Th17 cells, has been implicated in a number of models of autoimmunity. However, their role in transplantation remains undefined. This is despite studies showing a link between IL-17, a cytokine secreted by Th17 cells, and acute allograft rejection. This chapter summarises current evidence for a role of Th17 cells in transplant rejection, tolerance and ischaemia reperfusion injury.
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Chen, Y., Wood, K.J. (2009). Th17 cells in organ transplantation. In: Quesniaux, V., Ryffel, B., Di Padova, F. (eds) Th 17 Cells: Role in Inflammation and Autoimmune Disease. Progress in Inflammation Research. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8681-8_11
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DOI: https://doi.org/10.1007/978-3-7643-8681-8_11
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-7643-8680-1
Online ISBN: 978-3-7643-8681-8
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