Abstract
Metabolomics and metabonomics, as one of omics techniques, have been widely applied in many system bioscience researches for recent decades, such as disease diagnosis, toxicology, pharmaceutical and environmental research. Combining the advanced detection methods (either Nuclear Magnetic Resonance spectroscopy or Mass spectrometry) and multivariate pattern recognition techniques, it can be detect the characteristic metabolomic profile from biofluids or tissue. The metabolites as a “signature” can display the result from the role of genes and proteins, and also can be informed the dynamic “signals” from disease or abnormal condition of organism. Oral cancer, periodontal disease and dental caries disease are still influence the oral health in the world. According to a WHO publication [21], oral health is one of focus on priority to solved problems. This publication suggests the aim of our researcher need to action. The metabolomics and metabonomics method can provide us an integrated view of biochemistry during the process of oral disease developing. It would give us a chance to make earlier diagnosis for oral cancer, stop the development during the premalignant lesions. It would help us find the factors lead the gingivitis reverse to periodontitis. It would find effect method to keep oral health easier.
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Zhou, J., Li, W. (2012). Introducing the Metabolomics Method into Oral Science to Find Something New. In: Sasaki, K., Suzuki, O., Takahashi, N. (eds) Interface Oral Health Science 2011. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54070-0_6
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DOI: https://doi.org/10.1007/978-4-431-54070-0_6
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-54069-4
Online ISBN: 978-4-431-54070-0
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