Abstract
There are many works on synthesis of valuable substances through condensation or transferase action by using hydrolytic enzymes, such as proteinases [1,2] or lipases [3]. However, few attempt has been reported for aminoacylase-catalyzed synthesis of N-acyl amino acid from amino acid and fatty acid or its ethyl ester [4]. Especially, fatty acid or its ester with the acyl-chain longer than 3 has not been used for the synthesis. In this study we tried to synthesize N-acyl amino acids with the acyl-chain of 2 to 7 from fatty acid or its ethyl ester and L-methionine or L-tryptophan by aminoacylase through condensation and transesterification. The products, N-acyl amino acids with longer acyl-chains, may be usable as safe biosurfactants.
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References
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© 1992 Springer-Verlag Tokyo
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Kimura, Y., Kobayashi, Y., Adachi, S., Matsuno, R. (1992). Aminoacylase-Catalyzed Synthesis of N-Acyl Amino Acid from Fatty Acid or Its Ethyl Ester and Amino Acid. In: Furusaki, S., Endo, I., Matsuno, R. (eds) Biochemical Engineering for 2001. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68180-9_27
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DOI: https://doi.org/10.1007/978-4-431-68180-9_27
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68182-3
Online ISBN: 978-4-431-68180-9
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