Summary
The long-term prognosis and outcome study of elderly hypertensives was based on the 20-year prospective population survey conducted in a Japanese rural community, Hisayama; and the results were compared with those for younger subjects. The survival curves for the study population which were related to blood pressure levels decreased with the elevation of either systolic or diastolic pressure in both the younger and elderly groups. The survival curves decreased markedly beyond the 160 mmHg boundary for systolic pressure or the 100 mmHg boundary for diastolic pressure for those aged 40–59 years. There was however, no cutoff level for increased mortality in either systolic or diastolic pressure for those aged 60 or over. Mortality from stroke or heart disease was higher in diastolic or systolic hypertensives than in normotensives for the aged. However, the relative risk of death by stroke in either hypertensive group was attenuated compared to that for the younger subjects. Intracerebral hemorrhage and cerebral infarction occurred more frequently in diastolic hypertensives for both younger and elderly subjects, even though the imbalance of frequency in age, sex, electrocardiographic abnormalities and diabetes mellitus was corrected by Cox’s Proportional hazard model. Systolic hypertension was strongly related to cerebral infarction in the aged and to myocardial infarction in both younger and elderly persons.
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© 1989 Springer Japan
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Ueda, K., Omae, T., Hasuo, Y., Fujishima, M. (1989). Morbidity and Mortality of Elderly Hypertensives: Results from the Long-Term Prospective Study in Hisayama, a Japanese Community. In: Omae, T., Zanchetti, A. (eds) How Should Elderly Hypertensive Patients Be Treated?. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68340-7_1
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DOI: https://doi.org/10.1007/978-4-431-68340-7_1
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