Abstract
Formation of the center-surround organization of the receptive field is one of the most important functions of the vertebrate retina, and many studies have been reported on its mechanism. Since the historical finding of [1] in turtle cones, it has been widely accepted that the feedback signal from the horizontal cell (HC) is responsible for the formation of the antagonistic surround response of cone photoreceptors. Accumulating evidence has suggested that the feedback from HC to cones is mediated by y-aminobutyric acid (GABA); HCs are GABAergic, they release GABA upon depolarization, and GABA receptors are concentrated at the cone terminal. On the other hand, there are number of reports criticizing the GABA hypothesis of HC-cone feedback.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Reference
Baylor DA, Fuortes MG, O’Bryan PM (1971) Receptive fields of cones in the retina of the turtle. J Physiol 214: 265–294
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Tokyo
About this paper
Cite this paper
Kaneko, A., Hirasawa, H. (2003). Neural Circuit Contributing to the Formation of the Receptive Surround. In: Kaneko, A. (eds) The Neural Basis of Early Vision. Keio University International Symposia for Life Sciences and Medicine, vol 11. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68447-3_10
Download citation
DOI: https://doi.org/10.1007/978-4-431-68447-3_10
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68449-7
Online ISBN: 978-4-431-68447-3
eBook Packages: Springer Book Archive