Skip to main content
SpringerLink
Log in

Uterus Transplantation

  • Chapter
Hand Transplantation

Abstract

Uterine transplant is at a crossroads. It is possibly the best solution for approximately 4% of infertile women who undergo the frustration of being unable to conceive due to the absence of a uterus. In some cases, this absence is due to congenital abnormality (e.g. Rokitansky’s syndrome). In other cases, it is due to surgical removal of the uterus at a relatively young age due to clinical emergencies, such as obstetric uterine rupture.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 229.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Fageeh W, Raffa H, Jabbad H et al (2002) Transplantation of the human uterus. Int J Gynaecol Obstet 76(3):245–251

    Article  PubMed  CAS  Google Scholar 

  2. Nahum GG (1998) Uterine anomalies. How common are they, and what is their distribution among subtypes? J Reprod Med 43(10):877–887

    PubMed  CAS  Google Scholar 

  3. Brinsden PR (2001) Gestational surrogacy. In: Howles CM (ed) Textbook of assisted reproductive techniques: laboratory and clinical perspectives. Martin Dunitz, London

    Google Scholar 

  4. Ber R (2000) Ethical issues in gestational surrogacy. Theor Med Bioeth 21(2):153–169

    Article  PubMed  CAS  Google Scholar 

  5. Cohen J, Jones HW (2001) Worldwide legislation. In: Howles CM (ed) Textbook of assisted reproductive techniques: laboratory and clinical perspectives. Martin Dunitz, London

    Google Scholar 

  6. www.uterinetransplant.com/history.html

    Google Scholar 

  7. Eraslan S, Hamernik RJ, Hardy JD (1966) Replantation of uterus and ovaries in dogs, with successful pregnancy. Arch Surg 92(1):9–12

    PubMed  CAS  Google Scholar 

  8. Confino E, Vermesh M, Thomas W Jr et al (1986) Nonvascular transplantation of the rabbit uterus. Int J Gynaecol Obstet 24(4):321–325

    Article  PubMed  CAS  Google Scholar 

  9. Zhordania I, Gotsiridze O (1964) Vital activity of the excised uterus and its appendages after their autotransplantation into omentum. Acta Chir Plast (Praha) 6(1):23–32

    PubMed  CAS  Google Scholar 

  10. Yonemoto RH, Du Sold WD, Deliman RM (1969) Homotransplantation of uterus and ovaries in dogs. A preliminary report. Am J Obstet Gynecol 104(8): 1143–1151

    PubMed  CAS  Google Scholar 

  11. O’Leary JA, Feldman M, Gaensslen DM (1969) Uterine and tubal transplantation. Fertil Steril 20(5):757–760

    PubMed  CAS  Google Scholar 

  12. Mattingly RF, Clark DO, Lutsky II et al (1970) Ovarian function in-utero ovarian homotransplantation. Am J Obstet Gynecol 108(5): 773–794

    PubMed  CAS  Google Scholar 

  13. Scott JR, Pitkin RM, Yannone ME (1971) Transplantation of the primate uterus. Surg Gynecol Obstet 133(3):414–418

    PubMed  CAS  Google Scholar 

  14. Barzilai A, Paldi E, Gal D et al (1973) Autotransplantation of the uterus and ovaries in dogs. Isr J Med Sci 9(1):49–52

    PubMed  CAS  Google Scholar 

  15. Schmid BP (1984) Monitoring of organ formation in rat embryos after in vitro exposure to azathioprine, mercaptopurine, methotrexate or cyclosporine A. Toxicology 31(1):9–12

    Article  PubMed  CAS  Google Scholar 

  16. Park-Wyllie L, Mazzotta P, Pastuszak A et al (2000) Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies. Teratology 62(6):385–392

    Article  PubMed  CAS  Google Scholar 

  17. Bar OB, Hackman R, Einarson T et al (2001) Pregnancy outcome after cyclosporine therapy during pregnancy: a meta-analysis. Transplantation 71(8):1051–1055

    Article  Google Scholar 

  18. Brännström M, Wranning CA, El Akouri RR (2003) Transplantation of the uterus. Mol Cell Endocrinol 202:177–184

    Article  PubMed  Google Scholar 

  19. Hunt RB (1992) Complications of infertility surgery. In: Hunt RB (ed) Atlas of female infertility surgery, 2nd Edn. Mosby Year Book, St. Louis, pp 485–495

    Google Scholar 

  20. Denjean R, Boeck W, Gordts S, Brosens I (1982) Ovarian transplantation by selective microvascular anastomosis in the rabbit. Br J Obstet Gynaecol 89:652–656

    PubMed  CAS  Google Scholar 

  21. Turunen A (1967) On traumatic amenorrhea: 2 cases of endometrium transplantation which led to the birth of a full term infant. Gynecologia 164:12–23

    CAS  Google Scholar 

  22. Gary G (1991) Anatomic exposure in vascular surgery. Williams and Wilkins, Philadelphia, pp 446–448

    Google Scholar 

  23. Hall TS, Baumgardner WA, Borkon AM et al (1980) Diagnosis of acute cardiac rejection with antimyosin monoclonal antibodies, phosphorus nuclear magnetic resonance imaging, two-dimensional echocardiography and endomyocardial biopsy. J Heart Transpl 5:419–424

    Google Scholar 

  24. Organ transplantation: an update (1996) Archives of the XVI International Congress of the Transplant Society, pp 1–6

    Google Scholar 

  25. Von Theobald P, Roffe JL, Berrocal J et al (1987) Heterotopic autotransplantation of the ovary in women. Presse Med 16:1239–1241

    Google Scholar 

  26. Carmona F, Ballash J, Gonzales MJ (1993) Ovarian function and tubal viability and pregnancy after tuboovarian transplantation in the rabbit. Human Reprod 8:929–931

    CAS  Google Scholar 

  27. Baughman L (1990) Monitoring of allograft rejection. Heart and Heart-Lung Transplantation. WB Saunders, Philadelphia, pp 157–164

    Google Scholar 

  28. Kandela P (2000) Uterine transplantation failure causes Saudi Arabian government clampdown. Lancet 356:838

    PubMed  CAS  Google Scholar 

  29. Fageeh W (2001) Apology to Dr Wafa Mohammed Khalil Fageeh, obstetrician and gynaecologist and assistant professor at King Abdilaziz University, and her medical team. Lancet 358:1076

    Article  PubMed  CAS  Google Scholar 

  30. http://news.bbc.co.uk/2/hi/health/2205086.stm

    Google Scholar 

  31. http://news.bbc.co.uk/1/hi/health/1857426.stm

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Uterine Transplant Team, King Abdul Aziz University, Jeddah, Saudi Arabia

    Wafa Fageeh

  2. Hand Surgery and Microsurgery Unit, San Gerardo Hospital, Monza, Milan, Italy

    Giovanna Lucchini (Former Clinical Fellow)

Authors
  1. Wafa Fageeh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Giovanna Lucchini
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Italian Institute of Hand Surgery, Monza,Milan, Italy

    Marco Lanzetta (Director, Adjunct Professor and President) (Director, Adjunct Professor and President)

  2. University of Canberra, Australia

    Marco Lanzetta (Director, Adjunct Professor and President) (Director, Adjunct Professor and President)

  3. International Hand and Composite, Tissue Allograft Society, Australia

    Marco Lanzetta (Director, Adjunct Professor and President) (Director, Adjunct Professor and President)

  4. Department of Transplantation, Édouard Herriot Hospital, Lyon, France

    Jean-Michel Dubernard  & Palmina Petruzzo  & 

  5. Department of Surgery, University of Cagliari, Italy

    Palmina Petruzzo

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag Italia

About this chapter

Cite this chapter

Fageeh, W., Lucchini, G. (2007). Uterus Transplantation. In: Lanzetta, M., Dubernard, JM., Petruzzo, P. (eds) Hand Transplantation. Springer, Milano. https://doi.org/10.1007/978-88-470-0374-3_51

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-0374-3_51

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0373-6

  • Online ISBN: 978-88-470-0374-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation