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I deficit cognitivi nella sclerosi multipla

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I disturbi neuropsichiatrici nella sclerosi multipla

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La presenza di disturbi cognitivi nei pazienti con SM era stata già individuata da Charcot, come si può dedurre dalle sue descrizioni dellamalattia risalenti al 1877 [1]. Dopo un lungo periodo, in cui tali disturbi non hanno ricevuto la giusta attenzione dalla maggior parte degli autori, negli ultimi 30 anni sono stati fatti notevoli progressi nella comprensione delle loro caratteristiche quantitative e qualitative. Dati sulla frequenza dei disturbi cognitivi sono estremamente variabili e dipendono dalle metodologie utilizzate e dal tipo di pazienti esaminati. Secondo gli studi metodologicamente più corretti circa il 45-65% dei pazienti con SM mostra disfunzioni cognitive di una certa entità [2–6]. Si va da disturbi selettivi di specifiche funzioni sino a una compromissione grave e diffusa.

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Author information

Authors and Affiliations

  1. Dipartimento di Neuroscienze, Università degli Studi di Roma “Tor Vergata”, IRCCS Fondazione “Santa Lucia”, Roma

    U. Nocentini

  2. Centro Neurologico per le Terapie Sperimentali UOC Neurologia, Az. Osp. “S. Andrea”, Roma IRCCS Fondazione “Santa Lucia”, Roma

    S. Romano

  3. Dipartimento di Neuroscienze, Università degli Studi di Roma “Tor Vergata”, IRCCS Fondazione “Santa Lucia”, Roma

    C. Caltagirone

Authors
  1. U. Nocentini
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  2. S. Romano
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  3. C. Caltagirone
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Editors and Affiliations

  1. Dipartimento di Neuroscienze, Universitá degli Studi di Roma “Tor Vergata” IRCCS Fondazione “Santa Lucia”, Roma

    Ugo Nocentini  & Carlo Caltagirone  & 

  2. Dipartimento di Scienze Neurologiche, Seconda Universitá di Napoli — SUN, Napoli

    Gioacchino Tedeschi

  3. MRI Research Center Laboratorio SUN-FISM, Istituto Hermitage Capodimonte, Napoli

    Gioacchino Tedeschi

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Nocentini, U., Romano, S., Caltagirone, C. (2011). I deficit cognitivi nella sclerosi multipla. In: Nocentini, U., Caltagirone, C., Tedeschi, G. (eds) I disturbi neuropsichiatrici nella sclerosi multipla. Springer, Milano. https://doi.org/10.1007/978-88-470-1711-5_8

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