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Contribution of New Technologies to Endoscopic Imaging

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Ileoscopy

Abstract

A thorough endoscopic visualization of the small-bowel mucosa is essential for reaching an accurate diagnosis and treating the respective disease. Standard white-light endoscopes permit gross examination of the small-bowel mucosa. The introduction of magnification or zoom endoscopy has increased our ability to analyze the mucosal details. With the application of dyes and zoom-magnification endoscopy, further architectural features of the mucosa can be elucidated. New techniques, especially computed virtual chromoendoscopy (NBI, FICE, i-Scan), have enhanced the optical capabilities for the evaluation of gut mucosal lesions. Recently, confocal endomicroscopy was proposed for the study of the small-bowel mucosa.

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References

  1. Marvik R, Lango T (2006) High-definition television in medicine. Surg Endosc 20:349–350

    Article  PubMed  CAS  Google Scholar 

  2. Udagawa T, Amano M, Okada F (2001) Development of magnifying video endoscopes with high resolution. Dig Endosc 13:163–169

    Article  Google Scholar 

  3. Tanaka S, Kaltenbach T, Chayama K et al (2006) High-magnification colonoscopy. Gastrointest Endosc 64:604–613

    Article  PubMed  Google Scholar 

  4. Bruno MJ (2003) Magnification endoscopy, high resolution endoscopy, and chromoscopy towards a better optical diagnosis. Gut 52(Suppl 4):47–411

    Google Scholar 

  5. ASGE Technology Commitee (2009) Technology status evaluation report on high-resolution and high-magnification endoscopes. Gastrointest Endosc 69:399–407

    Article  Google Scholar 

  6. Yao K, Oishi T (2001) Microgastroscopic findings of mucosal microvascular architecture as visualized by magnifying endoscopy. Dig Endosc 13(Suppl):S27–S33

    Article  Google Scholar 

  7. Yagi K, Aruga Y, Nakamura A (2005) Magnifying endoscopy for diagnosis of gastric cancer. Stomach Intestine 40:791–799

    Google Scholar 

  8. Siegel LM, Stevens PD, Lightdale CJ et al (1997) Combined magnification endoscopy with chromoendoscopy in the evaluation of patients with suspected malabsorption. Gastrointest Endosc 46:226–230

    Article  PubMed  CAS  Google Scholar 

  9. Cammarota G, Martino A, Pirozzi GA et al (2004) Direct visualization of intestinal villi by high-resolution magnifying upper endoscopy: a validation study. Gastrointest Endosc 60:732–738

    Article  PubMed  Google Scholar 

  10. Cammarota G, Martino A, Di Caro S et al (2005) High-resolution magnifying upper endoscopy in a patient with patchy celiac disease. Dig Dis Sci 50:601–604

    Article  PubMed  Google Scholar 

  11. Cammarota G, Cianci R, Gasbarrini G (2005) High-resolution magnifying video endoscopy in primary intestinal lymphangiectasia: a new role for endoscopy? Endoscopy 37:607–610

    Article  PubMed  CAS  Google Scholar 

  12. Ishimoto H, Isomoto H, Shikuwa S, Wen CY, Suematu T, Ito M, Murata I, Ishibashi H, Kohno S (2004) Endoscopic identification of Peyer’s patches of the terminal ileum in a patient with Crohn’s disease. World J Gastroenterol 10(18):2767–2768

    PubMed  Google Scholar 

  13. Fujikura S (1984) A study of Peyer’s patch of the terminal ileum: a study of the mucosal surface appearance and histological finding in endoscopic cases and autopsy cases. Gastroenterol Endosc 26:1246–1261

    Google Scholar 

  14. Fishbein TM, Gondolesi GE, Kaufman SS (2003) Intestinal transplantation for gut failure. Gastroenterology 124:1615–1628

    Article  PubMed  Google Scholar 

  15. Kato T, Ruiz P, Thompson JF, Eskind LB, Weppler D, Khan FA, Pinna AD, Nery JR, Tzakis AG (2002) Intestinal and multivisceral transplantation. World J Surg 26:226–237

    Article  PubMed  Google Scholar 

  16. Mittal NK, Tzakis AG, Kato T, Thompson JF (2003) Current status of small bowel transplantation in children: update 2003. Pediatr Clin North Am 50:1419–1433

    Article  PubMed  Google Scholar 

  17. Ishii T, Mazariegos GV, Bueno J, Ohwada S, Reyes J (2003) Exfoliative rejection after intestinal transplantation in children. Pediatr Transplant 7:185–191

    Article  PubMed  Google Scholar 

  18. Kato T, Berho M, Weppler D, Ruiz P, Pinna AD, Khan FA, Nery JR, Tzakis AG (2000) Is severe rejection an indication for retransplantation? Transplant Proc 32:1201

    Article  PubMed  CAS  Google Scholar 

  19. Kato T (2000) New technique for prevention and treatment of rejection in intestinal transplantation. Curr Opin Organ Transplant 5:284–289

    Article  Google Scholar 

  20. Sigurdsson L, Reyes J, Putman PE, Del Rosario JF, DiLorenzo C, Orenstein SR, Todo S, Kocoshis SA (1998) Endoscopies in pediatric small intestinal transplant recipients: five-year experience. Am J Gastroenterol 93:207–211

    Article  PubMed  CAS  Google Scholar 

  21. Tabasco-Minguillan J, Hutson W, Weber K, Lee RG, Furukawa H, Abu-Elmagd K, Todo S, Rakela J (1996) Endoscopic features of acute cellular rejection. Transplant Proc 28:2765–2766

    PubMed  CAS  Google Scholar 

  22. Tabasco-Minguillan J, Weber K, Nelson F, Hutson W, Furukawa H, Abu-Elmagd K, Todo S, Rakela J (1998) Variability in the interpretations of endoscopic findings in patients with intestinal transplantation. Transplant Proc 28:2775–2776

    Google Scholar 

  23. Kato T, O'Brien CB, Nishida S, Hoppe H, Gasser M, Berho M, Rodriguez MJ, Ruiz P, Tzakis A (1999) The first case report of the use of a zoom videoendoscope for the evaluation of small bowel graft mucosa in a human after intestinal transplantation. Gastrointest Endosc 50:257–261

    Article  PubMed  CAS  Google Scholar 

  24. Kato T, Gaynor JJ, Nishida S, Mittal N, Selvaggi G, Levi D, Moon J, Thompson J, Ruiz P, Madariaga J, Tzakis AG (2006) Zoom endoscopic monitoring of small bowel allograft rejection. Surg Endosc 20:773–782

    Article  PubMed  CAS  Google Scholar 

  25. Pohl J, May A, Rabenstein T, Pech O, Ngyen-Tat M, Ell C (2007) Computed virtual chromoendoscopy vs. conventional chromoendoscopy with acetic acid for detection of neoplasia in barrett’s esophagus: a prospective randomized crossover. Study Gastrointest Endosc 65(5):AB348

    Google Scholar 

  26. Bosco JJ, Barkun AN, Isenberg GA (2003) Gastrointestinal endoscopes. Gastrointest Endosc 58:822–830

    Article  PubMed  Google Scholar 

  27. Technology Commitee ASGE (2008) Technology status evaluation report on narrow band imaging and multiband imaging. Gastrointest Endosc 67:589–589

    Google Scholar 

  28. Gono K, Obi T, Yamaguchi M et al (2004) Appearance of enhanced tissue features in narrow-band endoscopic imaging. J Biomed Opt 9:568–577

    Article  PubMed  Google Scholar 

  29. Yoshida T, Inoue H, Usui S et al (2004) Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions. Gastrointest Endosc 59:288–295

    Article  PubMed  Google Scholar 

  30. Muto M, Katada C, Sano Y et al (2005) Narrow band imaging: a new diagnostic approach to visualize angiogenesis in superficial neoplasia. Clin Gastroenterol Hepatol 3:S16–S20

    Article  PubMed  Google Scholar 

  31. Kuznetsov K, Lambert R, Rey JF (2006) Narrow-band imaging: potential and limitations. Endoscopy 38:76–81

    Article  PubMed  CAS  Google Scholar 

  32. Miyake Y, Kouzu T, Takeuchi S et al (2005) Development of new electronic endoscopes using the spectral images of an internal organ. In: Proceedings of the IS&T/SID’s Thirteen Color Imaging Conference, Scottsdale (Ariz), pp 261–269 November 7–11

    Google Scholar 

  33. Burgos H, Porras M, Brenes F, Izquierdo E (2007) Fujinon FICE Electronic Chromovideoendoscopy Helps Differentiate the Type of Metaplasia in Patients with Chronic Atrophic Gastritis Gastrointest Endosc 65(5):AB 353

    Google Scholar 

  34. Tajiri H, Niwa H (2008) Proposal for a consensus terminology in endoscopy: how should different endoscopic imaging techniques be grouped and defined? Endoscopy 40:775–778

    Article  PubMed  CAS  Google Scholar 

  35. Kodashima S, Fujishiro M (2010) Novel image-enhanced endoscopy with i-scan technology. World J Gastroenterol 16(9):1043–1049

    Article  PubMed  Google Scholar 

  36. Goetz M, Kiesslich R (2009) Advanced imaging of the gastrointestinal tract: research vs. clinical tools? Curr Opin Gastroenterol 25:412–421

    Article  PubMed  Google Scholar 

  37. Hoffman A, Kagel C, Goetz M et al (2010) Recognition and characterization of small colonic neoplasia with high-definition colonoscopy using i-Scan is as precise as chromoendoscopy. Dig Liver Dis 42:45–50

    Article  PubMed  CAS  Google Scholar 

  38. Hoffman A, Basting N, Goetz M et al (2009) High-definition endoscopy with i-Scan and Lugol’s solution for more precise detection of mucosal breaks in patients with reflux symptoms. Endoscopy 41:107–112

    Article  PubMed  CAS  Google Scholar 

  39. Neumann H, Fry LC, Bellutti M, Malfertheiner P, Mönkemüller K (2009) Double-balloon enteroscopy-assisted virtual chromoendoscopy for small-bowel disorders—a case series. Endoscopy 41:468–471

    Article  PubMed  CAS  Google Scholar 

  40. Mönkemüller K, Fry LC, Ebert M et al (2007) Feasibility of double-balloon enteroscopy-assisted chromoendoscopy of the small bowel in patients with familial adenomatous polyposis. Endoscopy 39:52–57

    Article  PubMed  Google Scholar 

  41. Ringold DA, Sikka S, Banerjee B (2008) High-contrast imaging (FICE) improves visualization of gastrointestinal vascular ectasias. Endoscopy 40(Suppl 2):E26

    Article  PubMed  Google Scholar 

  42. Pohl J, May A, Rabenstein T et al (2007) Computed virtual chromoendoscopy: a new tool for enhancing tissue surface structures. Endoscopy 39:80–83

    Article  PubMed  CAS  Google Scholar 

  43. East JE, Tan EK, Bergman JJ et al (2008) Meta-analysis: narrow band imaging for lesion characterization in the colon, oesophagus, duodenal ampulla and lung. Aliment Pharmacol Ther 28:854–867

    Article  PubMed  CAS  Google Scholar 

  44. Tajiri H, Matsuda K, Fujisaki J (2002) What can we see with the endoscope? Present status and future perspectives. Digestive Endoscopy 14:131–137

    Article  Google Scholar 

  45. Higuchi K, Komatsu K, Wakamatsu H et al (2007) Small intestinal follicular lymphoma with multiple tumor formations diagnosed by double-balloon enteroscopy. Intern Med 46:705–710

    Article  PubMed  Google Scholar 

  46. Liu YX, Huang LY, Bian XP, Cui J, Xu N, Wu CR (2008) Fuji intelligent chromo endoscopy and staining technique for the diagnosis of colon tumor. Chin Med J 121:977–982

    PubMed  Google Scholar 

  47. Pohl J, Aschmoneit I, Schuhmann S, Ell C (2010) Computed image modification for enhancement of small-bowel surface structures at video capsule endoscopy. Endoscopy 42:490–492

    Article  PubMed  CAS  Google Scholar 

  48. Wang TD (2005) Confocal microscopy from the bench to the bedside. Gastrointest Endosc 62:696–697

    Article  PubMed  Google Scholar 

  49. Polglase AL, McLaren WJ, Skinner SA et al (2005) A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract. Gastrointest Endosc 62:686–695

    Article  PubMed  Google Scholar 

  50. Technology Commitee ASGE (2009) Confocal laser endomicroscopy. Gastrointest Endosc 70:197–200

    Article  Google Scholar 

  51. Wang TD, Van Dam J (2004) Optical biopsy: a new frontier in endoscopic detection and diagnosis. Clin Gastroenterol Hepatol 2:744–753

    Article  PubMed  Google Scholar 

  52. Yoshida S, Tanaka S, Hirata M, Mouri R, Kaneko I, Oka S, Yoshihara M, Chayama K (2007) Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy. Gastrointest Endosc 66(1):144–149

    Google Scholar 

  53. Aisenberg J (2008) Gastrointestinal endoscopy nears “the molecular era”. Gastrointest Endosc 68:528–530

    Article  PubMed  Google Scholar 

  54. Inoue H, Cho JY, Satodate H et al (2003) Development of virtual histology and virtual biopsy using laser-scanning confocal microscopy. Scand J Gastroenterol 237:37–39

    Article  Google Scholar 

  55. Yoshida S, Tanaka S, Hirata M et al (2007) Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy. Gastrointest Endosc 66:144–149

    Article  PubMed  Google Scholar 

  56. Sakashita M, Inoue H, Kashida H et al (2003) Virtual histology of colorectal lesions using laser-scanning confocal microscopy. Endoscopy 35:1033–1038

    Article  PubMed  CAS  Google Scholar 

  57. Kiesslich R, Neurath MF (2006) Chromoendoscopy and other novel imaging techniques. Gastroenterol Clin North Am 35:605–619

    Article  PubMed  Google Scholar 

  58. Becker V, Vercauteren T, von Weyhern CH et al (2007) High-resolution miniprobe-based confocal microscopy in combination with video mosaicing. Gastrointest Endosc 66:1001–1007

    Article  PubMed  Google Scholar 

  59. von Delius S, Feussner H, Wilhelm D et al (2007) Transgastric in vivo histology in the peritoneal cavity using miniprobe-based confocal fluorescence microscopy in an acute porcine model. Endoscopy 39:407–411

    Article  Google Scholar 

  60. Goetz M, Hoffman A, Galle PR et al (2006) Confocal laser endoscopy: new approach to the early diagnosis of tumors of the esophagus and stomach. Future Oncol 2:469–476

    Article  PubMed  Google Scholar 

  61. Hurlstone DP, Kiesslich R, Thomson M et al (2008) Confocal chromoscopic endomicroscopy is superior to chromoscopy alone for the detection and characterisation of intraepithelial neoplasia in chronic ulcerative colitis. Gut 57:196–204

    Article  PubMed  CAS  Google Scholar 

  62. Burleson GR, Caulfield MJ, Pollard M (1979) Ozonation of mutagenic and carcinogenic polyaromatic amines and polyaromatic hydrocarbons in water. Cancer Res 39:2149–2154

    PubMed  CAS  Google Scholar 

  63. Mönkemüller K, Neumann H, Fry LC (2009) endoscopic examination of the small bowel: from standard white light to confocal endomicroscopy. Clinic Gastroenterol Hepatol 7:11–12

    Article  Google Scholar 

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Correspondence to Giuseppe Galloro .

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Galloro, G., Magno, L., Ruggiero, S., Fusco, F., Rappa, T. (2012). Contribution of New Technologies to Endoscopic Imaging. In: Trecca, A. (eds) Ileoscopy. Springer, Milano. https://doi.org/10.1007/978-88-470-2345-1_4

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  • DOI: https://doi.org/10.1007/978-88-470-2345-1_4

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