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Abstract

With ≈ 1 million of new cases per year separated into 72% for the colon and 28% for the rectum, colorectal cancer (CRC) is the fourth most common cancer in men (after cancer of the lung, prostate and stomach) and the third most common in women (after cancer of the breast and cervix) without significant differences in incidence by sex (male:female ratio of 1.2:1). The areas with the highest incidence rates are Australia and New Zealand, North America, Japan and western Europe [1]. In 2002, it resulted in ≈ 8% of the 6,724,000 registered deaths for cancer. It is estimated that 83% of cases occur in patients aged >60 years and the average age at diagnosis is 70 years. Unfortunately, the incidence of CRC is escalating in patients younger than 50 years, with an increased rate of 56% for patients aged 40–44 years over the past two decades

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Corcione, F., Angelini, P., Miranda, L. (2013). Colon Cancer. In: Valeri, A., Bergamini, C., Agresta, F., Martellucci, J. (eds) What’s New in Surgical Oncology. Springer, Milano. https://doi.org/10.1007/978-88-470-5310-6_3

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