Abstract
We present the overview of the multiscale approach to radiation damage by ions. This approach has been designed to understand the effects happening on different scales in time, space, and energy, which influence the cell damage following irradiation by ions. The multiscale approach includes the topics starting from the energy loss by projectiles and production of secondaries to the pathways of cell damage. This particular paper is devoted to the analysis of complex damage of DNA. The complex damage is important because cells in which it occurs are less likely to survive. We consider several possible approaches to the calculation of complex damage and suggest different developments involving comparisons with experiments.
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Acknowledgements
We are grateful to the support of the authors’ collaboration by the Deutsche Forschungsgemeinschaft.
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Solov’yov, A.V., Surdutovich, E. (2012). Multiscale Approach to Radiation Damage Induced by Ions. In: García Gómez-Tejedor, G., Fuss, M. (eds) Radiation Damage in Biomolecular Systems. Biological and Medical Physics, Biomedical Engineering. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2564-5_17
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DOI: https://doi.org/10.1007/978-94-007-2564-5_17
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